HitPredict

Interactor 1: DPYL2 (Q16555)
Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (N2A3) (Unc-33-like phosphoprotein 2) (ULIP-2)
Gene: DPYSL2

Interactor 2: Q8IXW6 (Q8IXW6)
Dihydropyrimidinase-like 3
Gene: DPYSL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Amidohydro_1~Amidohydro_1
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 572 Hs			1 570
+	Hs
		1050916 DPYL2_HUMAN (1-572): 0: 769: 100.00		DPYL3_HUMAN (1-570): 0: 765: 99.83
+	Hs
		1050861 DPYL1_HUMAN (1-572): 0: 761: 76.22		DPYL3_HUMAN (1-570): 0: 765: 99.83
+	Hs
		1050867 DPYL2_HUMAN (1-572): 0: 769: 100.00		DPYL1_HUMAN (1-569): 0: 748: 74.43
+	Mm
		956446 DPYL1_MOUSE (1-572): 0: 752: 76.22		DPYL3_MOUSE (1-570): 0: 764: 98.25
+	Hs
		1083101 DPYL2_HUMAN (1-572): 0: 769: 100.00		DPYL2_HUMAN (1-569): 0: 742: 76.53
+	Hs
		1050860 DPYL1_HUMAN (1-572): 0: 761: 76.22		DPYL1_HUMAN (1-569): 0: 748: 74.43
+	Mm
		139071 DPYL2_MOUSE (1-572): 0: 768: 98.78		DPYL2_MOUSE (1-569): 0: 740: 77.23
+	Rn
		815101 DPYL2_RAT (1-572): 0: 768: 98.78		DPYL2_RAT (1-569): 0: 740: 77.23
+	Mm
		139110 DPYL2_MOUSE (1-572): 0: 768: 98.78		DPYL1_MOUSE (1-569): 0: 738: 74.43
+	Hs
		147335 DPYL2_HUMAN (1-572): 0: 769: 100.00		DPYL4_HUMAN (1-570): 0: 730: 70.11
+	Hs
		147331 DPYL1_HUMAN (1-572): 0: 761: 76.22		DPYL4_HUMAN (1-570): 0: 730: 70.11
+	Hs
		1083161 DPYL2_HUMAN (1-572): 0: 769: 100.00		X5DQV1_HUMAN (14-569): 0: 720: 74.19
+	Mm
		956442 DPYL1_MOUSE (1-572): 0: 752: 76.22		Q3TMU8_MOUSE (1-570): 0: 731: 70.11
+	Hs
		147332 DPYL3_HUMAN (1-571): 0: 744: 76.71		DPYL4_HUMAN (1-570): 0: 730: 70.11
+	Hs
		1048473 DPYL2_HUMAN (1-572): 0: 769: 100.00		DPYS_HUMAN (16-522): 0: 649: 58.90
+	Hs
		1083135 DPYL2_HUMAN (1-572): 0: 769: 100.00		DPYL5_HUMAN (9-565): 0: 649: 50.54
+	Mm
		139196 DPYL2_MOUSE (1-572): 0: 768: 98.78		DPYL5_MOUSE (9-565): 0: 642: 50.36
+	Hs
		1048471 DPYL3_HUMAN (1-571): 0: 744: 76.71		DPYS_HUMAN (16-522): 0: 649: 58.90