HitPredict

Interactor 1: SYPL1 (Q16563)
Synaptophysin-like protein 1 (Pantophysin)
Gene: SYPL1

Interactor 2: VAMP8 (Q9BV40)
Vesicle-associated membrane protein 8 (VAMP-8) (Endobrevin) (EDB)
Gene: VAMP8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 259 Hs			1 100
+	Hs
		1079326 SYPL1_HUMAN (1-259): 2.65e-154: 431: 100.00		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		926212 SYPL1_HUMAN (1-259): 2.65e-154: 431: 100.00		VAMP2_HUMAN (6-82): 2.47e-23: 88: 35.07
+	Hs
		439113 SYPH_HUMAN (7-256): 5.56e-138: 392: 42.63		VAMP2_HUMAN (6-82): 2.47e-23: 88: 35.07
+	Mm
		926338 SYPH_MOUSE (7-256): 7.51e-136: 387: 42.63		VAMP2_MOUSE (6-82): 2.47e-23: 88: 35.07
+	Rn
		431095 SYPH_RAT (12-256): 1.98e-135: 385: 43.09		VAMP2_RAT (6-82): 2.47e-23: 88: 35.07
+	Hs
		1079344 SYPL2_HUMAN (9-239): 1.03e-117: 339: 40.95		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99