HitPredict

Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: SIR7 (Q9NRC8)
NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
Gene: SIRT7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28886238, 22586326
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 400
+	Hs
		1344499 NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		997925 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		929682 RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1083312 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		1083343 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		SIR1_HUMAN (78-380): 5.06e-78: 257: 19.94
+	Hs
		997813 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		997850 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		SIR1_HUMAN (78-380): 5.06e-78: 257: 19.94