Protein: ARI4B
AT-rich interactive domain-containing protein 4B (ARID domain-containing protein 4B) (180 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p180) (Breast cancer-associated antigen BRCAA1) (Histone deacetylase complex subunit SAP180) (Retinoblastoma-binding protein 1-like 1)

Gene: ARI4B, ARID4B
Organism: Homo sapiens
Interactions: 173
UniProt ID: Q4LE39

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

210289

PHF1
PHD finger protein 1

2

4

Small-scale

0.754

High

1109782

HDAC1
Histone deacetylase 1

7

20

Small-scale

0.749

High

1158865

RBBP7
Histone-binding protein RBBP7

5

14

High-throughput

0.712

High

1066331

RBBP4
Histone-binding protein RBBP4

4

14

High-throughput

0.697

High

1195603

SHCAF
SIN3-HDAC complex-associated factor

4

1

Small-scale

0.691

High

282263

SAP30
Histone deacetylase complex subunit SAP30

3

1

High-throughput

0.667

High

1050739

MAD1
Max dimerization protein 1

3

20

High-throughput

0.667

High

1195577

HDAC2
Histone deacetylase 2

3

20

Small-scale

0.667

High

1195599

ING2
Inhibitor of growth protein 2

3

15

Small-scale

0.667

High

1195562

ZN704
Zinc finger protein 704

3

1

High-throughput

0.662

High

274338

SIN3B
Paired amphipathic helix protein Sin3b

3

8

High-throughput

0.650

High

712871

CASP1
Caspase-1

3

0

High-throughput

0.638

High

846128

CATK
Cathepsin K

3

0

High-throughput

0.638

High

1195566

LACC1
Purine nucleoside phosphorylase LACC1

3

0

High-throughput

0.638

High

1195569

YAF2
YY1-associated factor 2

2

1

High-throughput

0.628

High

1195594

MAD3
Max dimerization protein 3

2

20

High-throughput

0.628

High

711771

ARI4A
AT-rich interactive domain-containing protein 4A

1

14

Small-scale

0.618

High

1086776

BPTF
Nucleosome-remodeling factor subunit BPTF

1

18

High-throughput

0.618

High

1088379

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

15

High-throughput

0.618

High

1195572

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

15

High-throughput

0.618

High

1195586

PHF12
PHD finger protein 12

1

20

High-throughput

0.618

High

1195619

MTF2
Metal-response element-binding transcription factor 2

1

4

High-throughput

0.618

High

487383

PARP1
Poly [ADP-ribose] polymerase 1

2

12

High-throughput

0.611

High

1195576

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

7

High-throughput

0.606

High

1195583

EAF1
ELL-associated factor 1

2

1

High-throughput

0.606

High

1195592

AASD1
Alanyl-tRNA editing protein Aarsd1

2

1

High-throughput

0.606

High

1195593

PHF23
PHD finger protein 23

2

0

High-throughput

0.602

High

474030

NFIC
Nuclear factor 1 C-type

2

20

High-throughput

0.584

High

944671

KLF3
Krueppel-like factor 3

2

20

High-throughput

0.584

High

980812

H2B1C
Histone H2B type 1-C/E/F/G/I

2

20

High-throughput

0.584

High

1087775

NFIA
Nuclear factor 1 A-type

2

20

High-throughput

0.584

High

1115230

CUL4B
Cullin-4B

2

10

Small-scale

0.584

High

1133442

NFIX
Nuclear factor 1 X-type

2

20

High-throughput

0.584

High

1195574

GATD1
GATA zinc finger domain-containing protein 1

2

3

High-throughput

0.584

High

1195588

SIN3A
Paired amphipathic helix protein Sin3a

2

8

Small-scale

0.584

High

1195598

SP130
Histone deacetylase complex subunit SAP130

2

11

Small-scale

0.584

High

1195601

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

2

4

Small-scale

0.584

High

1195582

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1195606

SPNXB
Sperm protein associated with the nucleus on the X chromosome B1

2

0

High-throughput

0.580

High

577444

ETS1
Protein C-ets-1

1

20

High-throughput

0.578

High

991854

DYLT1
Dynein light chain Tctex-type 1

2

3

High-throughput

0.553

High

1195602

PKHF2
Pleckstrin homology domain-containing family F member 2

2

6

High-throughput

0.553

High

890499

RBP2
E3 SUMO-protein ligase RanBP2

1

7

High-throughput

0.541

High

228083

PM34
Peroxisomal membrane protein PMP34

1

2

High-throughput

0.536

High

502007

H2AZ
Histone H2A.Z

1

15

High-throughput

0.536

High

542054

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.536

High

625422

CSK22
Casein kinase II subunit alpha'

1

9

High-throughput

0.536

High

913506

KIF11
Kinesin-like protein KIF11

1

1

High-throughput

0.536

High

959593

MAX
Protein max

1

20

High-throughput

0.536

High

997759

CSK21
Casein kinase II subunit alpha

1

10

High-throughput

0.536

High

1017430

FOXK1
Forkhead box protein K1

1

20

High-throughput

0.536

High

1029690

FOXK2
Forkhead box protein K2

1

20

High-throughput

0.536

High

1040727

ENL
Protein ENL

1

5

High-throughput

0.536

High

1122988

FHL2
Four and a half LIM domains protein 2

1

13

High-throughput

0.536

High

1162949

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.536

High

1195565

TF2LX
Homeobox protein TGIF2LX

1

8

High-throughput

0.536

High

1195597

TGIF2
Homeobox protein TGIF2

1

4

High-throughput

0.536

High

1195614

ING1
Inhibitor of growth protein 1

1

15

High-throughput

0.536

High

116821

I6L957
Heterogeneous nuclear ribonucleoproteins A2/B1

1

12

High-throughput

0.515

High

1195613

DDX41
Probable ATP-dependent RNA helicase DDX41

1

0

High-throughput

0.513

High

1195622

SNX5
Sorting nexin-5

1

0

High-throughput

0.513

High

1195578

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.493

High

706142

S10A2
Protein S100-A2

1

4

High-throughput

0.489

High

1195610

DKK2
Dickkopf-related protein 2

1

1

High-throughput

0.489

High

650790

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

11

High-throughput

0.481

High

138142

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

3

High-throughput

0.479

High

143028

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

168261

HAT1
Histone acetyltransferase type B catalytic subunit

1

1

High-throughput

0.479

High

181519

TBXT
T-box transcription factor T

1

10

High-throughput

0.479

High

190935

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

6

High-throughput

0.479

High

210010

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.479

High

225018

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.479

High

248307

HBP1
HMG box-containing protein 1

1

20

High-throughput

0.479

High

285319

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

316877

MTA2
Metastasis-associated protein MTA2

1

11

High-throughput

0.479

High

339766

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

352156

MBD3
Methyl-CpG-binding domain protein 3

1

5

High-throughput

0.479

High

404104

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

412036

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.479

High

447773

TPM3
Tropomyosin alpha-3 chain

1

1

High-throughput

0.479

High

464976

SP1
Transcription factor Sp1

1

20

High-throughput

0.479

High

519516

MYBB
Myb-related protein B

1

7

High-throughput

0.479

High

535140

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.479

High

538404

EGR2
E3 SUMO-protein ligase EGR2

1

6

High-throughput

0.479

High

540883

ERG
Transcriptional regulator ERG

1

20

High-throughput

0.479

High

559974

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

1

High-throughput

0.479

High

581665

MYOD1
Myoblast determination protein 1

1

8

High-throughput

0.479

High

591678

H2AX
Histone H2AX

1

15

High-throughput

0.479

High

662233

PAX7
Paired box protein Pax-7

1

20

High-throughput

0.479

High

662437

GATA2
Endothelial transcription factor GATA-2

1

17

High-throughput

0.479

High

675528

TYY1
Transcriptional repressor protein YY1

1

5

High-throughput

0.479

High

680378

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

3

High-throughput

0.479

High

685213

PAX6
Paired box protein Pax-6

1

17

High-throughput

0.479

High

697135

APEX1
DNA repair nuclease/redox regulator APEX1

1

3

High-throughput

0.479

High

703152

TEAD1
Transcriptional enhancer factor TEF-1

1

8

High-throughput

0.479

High

703331

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

1

20

High-throughput

0.479

High

725262

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.479

High

738989

ELF1
ETS-related transcription factor Elf-1

1

20

High-throughput

0.479

High

764806

CTNB1
Catenin beta-1

1

4

High-throughput

0.479

High

775850

HNF1B
Hepatocyte nuclear factor 1-beta

1

20

High-throughput

0.479

High

776078

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.479

High

776201

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

833960

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

837050

ELK3
ETS domain-containing protein Elk-3

1

20

High-throughput

0.479

High

872392

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.479

High

873091

SOX9
Transcription factor SOX-9

1

20

High-throughput

0.479

High

881535

CDK8
Cyclin-dependent kinase 8

1

8

High-throughput

0.479

High

895727

LHX2
LIM/homeobox protein Lhx2

1

20

High-throughput

0.479

High

938456

PAX9
Paired box protein Pax-9

1

17

High-throughput

0.479

High

942102

SOX10
Transcription factor SOX-10

1

20

High-throughput

0.479

High

942439

GSC
Homeobox protein goosecoid

1

19

High-throughput

0.479

High

979760

H4
Histone H4

1

10

High-throughput

0.479

High

998384

H31
Histone H3.1

1

20

High-throughput

0.479

High

1016909

H33
Histone H3.3

1

20

High-throughput

0.479

High

1029103

E2F1
Transcription factor E2F1

1

10

High-throughput

0.479

High

1037799

IRF8
Interferon regulatory factor 8

1

9

High-throughput

0.479

High

1037866

HEN1
Helix-loop-helix protein 1

1

8

High-throughput

0.479

High

1040051

PAX2
Paired box protein Pax-2

1

18

High-throughput

0.479

High

1052031

CALD1
Caldesmon

1

11

High-throughput

0.479

High

1052872

HME1
Homeobox protein engrailed-1

1

14

High-throughput

0.479

High

1091215

FOXI1
Forkhead box protein I1

1

20

High-throughput

0.479

High

1091293

FOXL1
Forkhead box protein L1

1

20

High-throughput

0.479

High

1094687

CAF1A
Chromatin assembly factor 1 subunit A

1

7

High-throughput

0.479

High

1095087

KLF10
Krueppel-like factor 10

1

20

High-throughput

0.479

High

1102561

MTA1
Metastasis-associated protein MTA1

1

10

High-throughput

0.479

High

1118653

KLF9
Krueppel-like factor 9

1

20

High-throughput

0.479

High

1118713

KLF5
Krueppel-like factor 5

1

20

High-throughput

0.479

High

1119559

NFYC
Nuclear transcription factor Y subunit gamma

1

3

High-throughput

0.479

High

1135251

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

20

High-throughput

0.479

High

1152695

ELF2
ETS-related transcription factor Elf-2

1

20

High-throughput

0.479

High

1155431

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

High-throughput

0.479

High

1157744

DDB1
DNA damage-binding protein 1

1

2

Small-scale

0.479

High

1160851

TBR1
T-box brain protein 1

1

10

High-throughput

0.479

High

1195560

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

4

High-throughput

0.479

High

1195564

P66A
Transcriptional repressor p66-alpha

1

3

High-throughput

0.479

High

1195568

SMC5
Structural maintenance of chromosomes protein 5

1

14

High-throughput

0.479

High

1195570

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

1195571

SP7
Transcription factor Sp7

1

20

High-throughput

0.479

High

1195575

P66B
Transcriptional repressor p66-beta

1

3

High-throughput

0.479

High

1195579

FBXW7
F-box/WD repeat-containing protein 7

1

8

Small-scale

0.479

High

1195580

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

8

Small-scale

0.479

High

1195584

Z512B
Zinc finger protein 512B

1

10

High-throughput

0.479

High

1195585

PWP2A
PWWP domain-containing protein 2A

1

5

High-throughput

0.479

High

1195587

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1195589

FEV
Protein FEV

1

20

High-throughput

0.479

High

1195590

ELF4
ETS-related transcription factor Elf-4

1

20

High-throughput

0.479

High

1195591

MTA3
Metastasis-associated protein MTA3

1

14

High-throughput

0.479

High

1195595

KLF16
Krueppel-like factor 16

1

20

High-throughput

0.479

High

1195596

BC11B
B-cell lymphoma/leukemia 11B

1

3

High-throughput

0.479

High

1195600

BC11A
BCL11 transcription factor A

1

4

High-throughput

0.479

High

1195604

GCM1
Chorion-specific transcription factor GCMa

1

2

High-throughput

0.479

High

1195608

ZN219
Zinc finger protein 219

1

2

High-throughput

0.479

High

1195609

MBD2
Methyl-CpG-binding domain protein 2

1

5

High-throughput

0.479

High

1195611

HMGX4
HMG domain-containing protein 4

1

20

High-throughput

0.479

High

1195612

KLF15
Krueppel-like factor 15

1

20

High-throughput

0.479

High

1195615

BRPF3
Bromodomain and PHD finger-containing protein 3

1

13

High-throughput

0.479

High

1195617

FZR1
Fizzy-related protein homolog

1

15

High-throughput

0.479

High

1195618

ZN330
Zinc finger protein 330

1

3

High-throughput

0.479

High

1195620

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.479

High

1195559

NHSL2
NHS-like protein 2

1

6

High-throughput

0.470

High

155313

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.458

High

1195561

LIN9
Protein lin-9 homolog

1

0

High-throughput

0.458

High

1195567

BAP18
BPTF-associated chromatin complex component 1

1

0

High-throughput

0.458

High

1195581

LIN37
Protein lin-37 homolog

1

0

High-throughput

0.458

High

1195607

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1195573

MIPT3
TRAF3-interacting protein 1

1

1

High-throughput

0.457

High

372192

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.445

High

192495

INSI1
Insulin-induced gene 1 protein

1

1

High-throughput

0.437

High

1063300

GOGA2
Golgin subfamily A member 2

1

8

High-throughput

0.437

High

1195616

HECD1
E3 ubiquitin-protein ligase HECTD1

1

9

High-throughput

0.437

High

1195621

INSI2
Insulin-induced gene 2 protein

1

1

High-throughput

0.437

High

1195563

PR23B
Proline-rich protein 23B

2

0

High-throughput

0.316

High

1195605

DAAF6
Dynein axonemal assembly factor 6

2

0

High-throughput

0.316

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025