Interactor 1: FRDA (Q16595)
Frataxin, mitochondrial (EC 1.16.3.1) (Friedreich ataxia protein) (Fxn) [Cleaved into: Frataxin intermediate form (i-FXN); Frataxin(56-210) (m56-FXN); Frataxin(78-210) (d-FXN) (m78-FXN); Frataxin mature form (Frataxin(81-210)) (m81-FXN); Extramitochondrial frataxin]
Gene: FXN
Interactor 2: ISCU (Q9H1K1)
Iron-sulfur cluster assembly enzyme ISCU (NifU-like N-terminal domain-containing protein) (NifU-like protein)
Gene: ISCU
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31101807 |
| Identification Methods | bio-layer interferometry |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Frataxin_Cyay~NifU_N |
| Common GO terms | GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix GO:0005829 - cytosol GO:0006879 - intracellular iron ion homeostasis GO:0008198 - ferrous iron binding and 7 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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| + | Ec | |
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
