Protein: TACC3
Transforming acidic coiled-coil-containing protein 3 (ERIC-1)

Gene: TACC3
Organism: Homo sapiens
Interactions: 132
UniProt ID: Q9Y6A5

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0000922 - spindle pole
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007052 - mitotic spindle organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

160881

AURKA
Aurora kinase A

5

20

Small-scale

0.718

High

1047856

CKAP5
Cytoskeleton-associated protein 5

4

7

Small-scale

0.697

High

1350095

SLAI2
SLAIN motif-containing protein 2

3

5

High-throughput

0.675

High

1326047

NDEL1
Nuclear distribution protein nudE-like 1

3

8

Small-scale

0.672

High

840619

VASP
Vasodilator-stimulated phosphoprotein

3

4

High-throughput

0.667

High

1101702

KIZ
Centrosomal protein kizuna

3

0

High-throughput

0.646

High

649179

ARNT
Aryl hydrocarbon receptor nuclear translocator

2

10

Small-scale

0.643

High

320451

SNP29
Synaptosomal-associated protein 29

3

0

High-throughput

0.638

High

1345852

TB22B
TBC1 domain family member 22B

4

2

High-throughput

0.637

High

1378192

TACC3
Transforming acidic coiled-coil-containing protein 3

1

17

High-throughput

0.637

High

1292791

BORC6
BLOC-1-related complex subunit 6

4

2

High-throughput

0.633

High

1357240

FZR1
Fizzy-related protein homolog

2

8

Small-scale

0.631

High

505024

HSP7C
Heat shock cognate 71 kDa protein

2

6

High-throughput

0.628

High

1237908

ENAH
Protein enabled homolog

2

8

High-throughput

0.628

High

1355641

EVL
Ena/VASP-like protein

2

4

High-throughput

0.628

High

1300188

CIB3
Calcium and integrin-binding family member 3

3

2

High-throughput

0.616

High

1120354

CEP55
Centrosomal protein of 55 kDa

2

1

High-throughput

0.615

High

1254601

PKHO2
Pleckstrin homology domain-containing family O member 2

3

3

High-throughput

0.609

High

963075

BEX3
Protein BEX3

2

1

High-throughput

0.606

High

992411

KLC1
Kinesin light chain 1

2

1

High-throughput

0.606

High

1205211

CD20B
Cell division cycle protein 20 homolog B

2

10

High-throughput

0.606

High

1254541

CCHCR
Coiled-coil alpha-helical rod protein 1

2

15

High-throughput

0.606

High

1307553

GDF15
Growth/differentiation factor 15

2

1

High-throughput

0.606

High

1315989

BEX2
Protein BEX2

2

1

High-throughput

0.606

High

204463

MS18B
Protein Mis18-beta

2

0

High-throughput

0.602

High

976310

KIME
Mevalonate kinase

2

0

High-throughput

0.602

High

339206

EGFR
Epidermal growth factor receptor

1

13

Small-scale

0.582

High

1253325

MIEAP
Mitochondria-eating protein

2

0

High-throughput

0.580

High

1288800

DRC10
Dynein regulatory complex protein 10

2

0

High-throughput

0.580

High

1306625

GDIR3
Rho GDP-dissociation inhibitor 3

2

0

High-throughput

0.580

High

561322

CRIS2
Cysteine-rich secretory protein 2

2

1

High-throughput

0.574

High

1163317

CORO6
Coronin-6

2

5

High-throughput

0.574

High

1317968

ASPC1
Tether containing UBX domain for GLUT4

1

1

High-throughput

0.573

High

1103555

KLH38
Kelch-like protein 38

2

8

High-throughput

0.553

High

1138245

BRE1A
E3 ubiquitin-protein ligase BRE1A

2

17

High-throughput

0.553

High

1188266

NUP54
Nucleoporin p54

2

1

High-throughput

0.553

High

1335641

ARNT2
Aryl hydrocarbon receptor nuclear translocator 2

1

10

High-throughput

0.541

High

280089

MPDZ
Multiple PDZ domain protein

1

6

High-throughput

0.536

High

324144

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

664152

T2EB
Transcription initiation factor IIE subunit beta

1

1

High-throughput

0.536

High

740287

NUP62
Nuclear pore glycoprotein p62

1

4

High-throughput

0.536

High

764723

CUX1
Homeobox protein cut-like 1

1

16

High-throughput

0.536

High

837666

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

1

High-throughput

0.536

High

855771

KIF11
Kinesin-like protein KIF11

1

7

High-throughput

0.536

High

877397

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

5

High-throughput

0.536

High

933402

TBA1B
Tubulin alpha-1B chain

1

10

High-throughput

0.536

High

934041

TBB4B
Tubulin beta-4B chain

1

4

High-throughput

0.536

High

984688

CALD1
Caldesmon

1

18

High-throughput

0.536

High

1120834

KLH12
Kelch-like protein 12

1

7

High-throughput

0.536

High

1127350

TGO1
Transport and Golgi organization protein 1 homolog

1

12

High-throughput

0.536

High

1136497

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

2

High-throughput

0.536

High

1140881

RN123
E3 ubiquitin-protein ligase RNF123

1

4

High-throughput

0.536

High

1159153

ANM9
Protein arginine N-methyltransferase 9

1

1

High-throughput

0.536

High

1216186

RN135
E3 ubiquitin-protein ligase RNF135

1

4

High-throughput

0.536

High

1223736

RN168
E3 ubiquitin-protein ligase RNF168

1

3

High-throughput

0.536

High

1242244

SLAI1
SLAIN motif-containing protein 1

1

5

High-throughput

0.536

High

1296590

WDR90
WD repeat-containing protein 90

1

4

High-throughput

0.536

High

1357335

PRP19
Pre-mRNA-processing factor 19

1

7

High-throughput

0.536

High

1377940

IPP
Actin-binding protein IPP

1

7

High-throughput

0.536

High

1353865

MBD2
Methyl-CpG-binding domain protein 2

1

0

Small-scale

0.529

High

60660

VP37C
Vacuolar protein sorting-associated protein 37C

1

5

High-throughput

0.523

High

1191338

SNX20
Sorting nexin-20

1

2

High-throughput

0.523

High

1054282

SLBP
Histone RNA hairpin-binding protein

1

0

High-throughput

0.513

High

1273378

CLP1
Polyribonucleotide 5'-hydroxyl-kinase Clp1

1

0

High-throughput

0.513

High

1317679

PANK2
Pantothenate kinase 2, mitochondrial

1

0

High-throughput

0.513

High

1354037

S53A1
Solute carrier family 53 member 1

1

0

High-throughput

0.513

High

1378188

NFS1
Cysteine desulfurase

1

0

High-throughput

0.513

High

1357610

TTF2
Transcription termination factor 2

1

4

Small-scale

0.508

High

1271476

KAT2A
Histone acetyltransferase KAT2A

1

11

Small-scale

0.501

High

451627

CLCA
Clathrin light chain A

1

3

Small-scale

0.500

High

282292

CDKL5
Cyclin-dependent kinase-like 5

1

14

High-throughput

0.494

High

230458

ZC3H1
Zinc finger C3H1 domain-containing protein

1

1

High-throughput

0.489

High

876631

AF17
Protein AF-17

1

1

High-throughput

0.489

High

1123365

Q58EY0
RAR related orphan receptor B isoform 1

1

1

High-throughput

0.489

High

1244259

BD1L1
Biorientation of chromosomes in cell division protein 1-like 1

1

15

High-throughput

0.489

High

1300561

ARX
Homeobox protein ARX

1

2

High-throughput

0.489

High

1309462

KXDL1
KxDL motif-containing protein 1

1

4

High-throughput

0.489

High

1349262

HPBP1
Hsp70-binding protein 1

1

1

High-throughput

0.489

High

1349987

NHSL3
NHS-like protein 3

1

4

High-throughput

0.489

High

1232240

CLIP4
CAP-Gly domain-containing linker protein 4

1

11

High-throughput

0.481

High

1307600

AKAP9
A-kinase anchor protein 9

1

17

Small-scale

0.481

High

1335707

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

1

Small-scale

0.481

High

229215

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

232618

KDM1A
Lysine-specific histone demethylase 1A

1

3

High-throughput

0.479

High

408970

K1C18
Keratin, type I cytoskeletal 18

1

4

High-throughput

0.479

High

570239

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

672934

CDC27
Cell division cycle protein 27 homolog

1

2

Small-scale

0.479

High

749997

BRCA1
Breast cancer type 1 susceptibility protein

1

6

Small-scale

0.479

High

780411

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

896286

UBC12
NEDD8-conjugating enzyme Ubc12

1

4

High-throughput

0.479

High

909416

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

943924

RAE1L
mRNA export factor RAE1

1

8

Small-scale

0.479

High

1030132

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

2

High-throughput

0.479

High

1038854

HDAC1
Histone deacetylase 1

1

11

High-throughput

0.479

High

1042953

CUL3
Cullin-3

1

9

High-throughput

0.479

High

1077190

MARE1
Microtubule-associated protein RP/EB family member 1

1

10

High-throughput

0.479

High

1080824

ZYX
Zyxin

1

6

High-throughput

0.479

High

1148912

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

1172477

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.479

High

1271523

KAT2B
Histone acetyltransferase KAT2B

1

7

Small-scale

0.479

High

1315565

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

5

High-throughput

0.479

High

1326810

WWTR1
WW domain-containing transcription regulator protein 1

1

12

High-throughput

0.479

High

1346702

ARL8B
ADP-ribosylation factor-like protein 8B

1

6

High-throughput

0.479

High

1355040

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1356705

BAG5
BAG family molecular chaperone regulator 5

1

3

High-throughput

0.479

High

1305041

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

High-throughput

0.460

High

1175284

TBA1A
Tubulin alpha-1A chain

1

10

High-throughput

0.445

High

385811

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.437

High

981940

RON
Macrophage-stimulating protein receptor

1

12

High-throughput

0.437

High

1146221

DCA15
DDB1- and CUL4-associated factor 15

1

3

High-throughput

0.437

High

1189129

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1285407

PF21A
PHD finger protein 21A

1

5

High-throughput

0.437

High

1347006

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

9

High-throughput

0.437

High

87593

C9JZP6
Dehydrogenase/reductase 2

1

3

High-throughput

0.407

High

1238916

CBY2
Protein chibby homolog 2

2

0

High-throughput

0.328

High

1122059

CTSRT
Cation channel sperm-associated targeting subunit tau

2

0

High-throughput

0.316

High

224670

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

0

High-throughput

0.279

Low

225693

PCDH7
Protocadherin-7

1

0

High-throughput

0.279

Low

300510

FRYL
Protein furry homolog-like

1

0

High-throughput

0.279

Low

1102973

TUSC1
Tumor suppressor candidate gene 1 protein

1

0

High-throughput

0.279

Low

1137012

PR14L
Protein PRR14L

1

0

High-throughput

0.279

Low

1164421

F111B
Serine protease FAM111B

1

0

High-throughput

0.279

Low

1193246

ZER1
Protein zer-1 homolog

1

0

High-throughput

0.279

Low

1237855

CB069
Mitochondrial protein C2orf69

1

0

High-throughput

0.279

Low

1245507

SVIP
Small VCP/p97-interacting protein

1

0

High-throughput

0.279

Low

1300298

DEPD7
DEP domain-containing protein 7

1

0

High-throughput

0.279

Low

1335442

DEFM
Peptide deformylase, mitochondrial

1

0

High-throughput

0.279

Low

1336069

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.279

Low

1353964

ORC3
Origin recognition complex subunit 3

1

0

High-throughput

0.279

Low

1316856

ACE2
Angiotensin-converting enzyme 2

1

0

Small-scale

0.249

Low

1091195

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024