Interactor 1: FRDA (Q16595)
Frataxin, mitochondrial (EC 1.16.3.1) (Friedreich ataxia protein) (Fxn) [Cleaved into: Frataxin intermediate form (i-FXN); Frataxin(56-210) (m56-FXN); Frataxin(78-210) (d-FXN) (m78-FXN); Frataxin mature form (Frataxin(81-210)) (m81-FXN); Extramitochondrial frataxin]
Gene: FXN
Interactor 2: NFS1 (Q9Y697)
Cysteine desulfurase (EC 2.8.1.7)
Gene: NFS1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31101807 |
| Identification Methods | differential scanning calorimetry |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Aminotran_5~Frataxin_Cyay |
| Common GO terms | GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix GO:0005829 - cytosol GO:0016226 - iron-sulfur cluster assembly GO:0018283 - iron incorporation into metallo-sulfur cluster and 4 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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| + | Sc |  |
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| + | Ec | |
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| + | Ec | |
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
