HitPredict

Interactor 1: BAK (Q16611)
Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7)
Gene: BAK1

Interactor 2: MFN1 (Q8IWA4)
Mitofusin-1 (EC 3.6.5.-) (Fzo homolog) (Transmembrane GTPase MFN1)
Gene: MFN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	17606912, 19168699
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0008053 - mitochondrial fusion
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 741
+	Mm
		139732 BAK_MOUSE (1-211): 3.58e-90: 265: 76.78		MFN1_MOUSE (1-741): 0: 1198: 90.55
+	Mm
		139731 BAK_MOUSE (1-211): 3.58e-90: 265: 76.78		MFN2_MOUSE (1-737): 0: 1112: 64.55
+	Hs
		304835 BAK_HUMAN (1-211): 2.1e-84: 250: 100.00		MFN2_HUMAN (1-737): 0: 1096: 63.46