Protein: PDIP2
Polymerase delta-interacting protein 2 (38 kDa DNA polymerase delta interaction protein) (p38)

Gene: PDIP2, POLDIP2
Organism: Homo sapiens
Interactions: 198
UniProt ID: Q9Y2S7

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005911 - cell-cell junction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1490910

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

4

1

High-throughput

0.692

High

560932

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

2

1

High-throughput

0.640

High

1490904

PDIP2
Polymerase delta-interacting protein 2

1

1

High-throughput

0.618

High

1114705

CUL3
Cullin-3

2

3

High-throughput

0.611

High

951913

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

2

4

Small-scale

0.602

High

1123484

ICT1
Large ribosomal subunit protein mL62

2

0

High-throughput

0.585

High

1206038

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

2

High-throughput

0.573

High

1367640

ESR2
Estrogen receptor beta

2

1

High-throughput

0.571

High

348804

AIFM1
Apoptosis-inducing factor 1, mitochondrial

2

0

High-throughput

0.563

High

279980

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

351044

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

2

0

High-throughput

0.559

High

1087625

GRSF1
G-rich sequence factor 1

2

0

High-throughput

0.559

High

1162626

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

Small-scale

0.559

High

1453980

MRES1
Mitochondrial transcription rescue factor 1

2

0

High-throughput

0.559

High

1403476

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.554

High

551348

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.549

High

644142

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

0

High-throughput

0.547

High

998975

H31
Histone H3.1

2

0

High-throughput

0.547

High

1058360

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

2

0

Small-scale

0.547

High

1273919

BHA15
Class A basic helix-loop-helix protein 15

1

1

High-throughput

0.536

High

1397686

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.536

High

1431120

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

High-throughput

0.518

High

1310542

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.515

High

216852

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.513

High

1053319

MBTD1
MBT domain-containing protein 1

1

0

High-throughput

0.513

High

1101109

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1385578

ZN524
Zinc finger protein 524

1

0

High-throughput

0.513

High

1460232

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.513

High

1461615

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.513

High

1279422

DPOLN
DNA polymerase nu

1

0

Small-scale

0.504

High

423496

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

872913

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.500

High

916119

NKX25
Homeobox protein Nkx-2.5

1

2

High-throughput

0.500

High

1037910

HEN1
Helix-loop-helix protein 1

1

1

High-throughput

0.500

High

1057482

SOX4
Transcription factor SOX-4

1

1

High-throughput

0.500

High

1389942

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

0

High-throughput

0.493

High

647419

IDS
Iduronate 2-sulfatase

1

7

High-throughput

0.489

High

756594

GALNS
N-acetylgalactosamine-6-sulfatase

1

7

High-throughput

0.489

High

193644

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

0

High-throughput

0.486

High

1458558

HDAC6
Protein deacetylase HDAC6

1

0

High-throughput

0.486

High

1490909

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

226622

TLX2
T-cell leukemia homeobox protein 2

1

0

High-throughput

0.479

High

641288

FGFR2
Fibroblast growth factor receptor 2

1

0

High-throughput

0.479

High

877578

LHX1
LIM/homeobox protein Lhx1

1

0

High-throughput

0.479

High

143949

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

1

High-throughput

0.479

High

174644

TRI66
Tripartite motif-containing protein 66

1

1

High-throughput

0.479

High

183777

RT12
Small ribosomal subunit protein uS12m

1

1

High-throughput

0.479

High

282132

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

287414

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

302002

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

2

High-throughput

0.479

High

397271

ESR1
Estrogen receptor

1

1

High-throughput

0.479

High

856432

IF2M
Translation initiation factor IF-2, mitochondrial

1

2

High-throughput

0.479

High

888405

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

905313

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

971322

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

1024240

TFAM
Transcription factor A, mitochondrial

1

1

High-throughput

0.479

High

1083802

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

1106396

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

2

High-throughput

0.479

High

1107356

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

1108302

SQSTM
Sequestosome-1

1

1

High-throughput

0.479

High

1138781

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.479

High

1241859

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.479

High

1273037

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

2

High-throughput

0.479

High

1341351

COQ8A
Atypical kinase COQ8A, mitochondrial

1

1

High-throughput

0.479

High

1356903

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

3

High-throughput

0.479

High

1361710

CHC10
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial

1

1

High-throughput

0.479

High

1372484

TP4A1
Protein tyrosine phosphatase type IVA 1

1

5

High-throughput

0.479

High

1381145

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

4

High-throughput

0.479

High

1381781

FAKD4
FAST kinase domain-containing protein 4

1

2

High-throughput

0.479

High

1383581

MCUR1
Mitochondrial calcium uniporter regulator 1

1

1

High-throughput

0.479

High

1387084

COQ8B
Atypical kinase COQ8B, mitochondrial

1

1

High-throughput

0.479

High

1391875

AURKB
Aurora kinase B

1

1

High-throughput

0.479

High

1397198

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

1

High-throughput

0.479

High

1401662

EFGM
Elongation factor G, mitochondrial

1

4

High-throughput

0.479

High

1428835

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

1

High-throughput

0.479

High

1432654

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

1438094

RC3H2
Roquin-2

1

1

High-throughput

0.479

High

1459177

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

1459380

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

297077

DHRS3
Short-chain dehydrogenase/reductase 3

1

1

High-throughput

0.470

High

1458904

REV1
DNA repair protein REV1

1

0

Small-scale

0.460

High

1460259

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

Small-scale

0.460

High

50875

NDUF8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8

1

0

High-throughput

0.458

High

61688

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

66339

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

137850

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

275137

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

284009

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.458

High

302674

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

High-throughput

0.458

High

361670

OTC
Ornithine transcarbamylase, mitochondrial

1

0

High-throughput

0.458

High

364064

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

414889

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

471333

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

505468

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

519272

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

533088

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

590079

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

680547

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

696916

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

718055

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

High-throughput

0.458

High

786311

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

829016

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

842036

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

852082

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

882960

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

891900

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.458

High

1013477

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.458

High

1036008

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

1048760

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1090598

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

1117884

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

1137598

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1141076

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1142708

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1152501

T22D1
TSC22 domain family protein 1

1

0

High-throughput

0.458

High

1155926

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1205157

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

0

High-throughput

0.458

High

1207187

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1234574

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1271923

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1293478

NIT1
Deaminated glutathione amidase

1

0

High-throughput

0.458

High

1347814

SPT20
Spermatogenesis-associated protein 20

1

0

High-throughput

0.458

High

1384915

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1385350

F136A
Protein FAM136A

1

0

High-throughput

0.458

High

1388314

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1388463

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1393297

FMC1
Protein FMC1 homolog

1

0

High-throughput

0.458

High

1400843

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.458

High

1407385

COQ7
NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial

1

0

High-throughput

0.458

High

1411507

OVOL2
Transcription factor Ovo-like 2

1

0

Small-scale

0.458

High

1412484

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1412621

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.458

High

1413044

MTG1
Mitochondrial ribosome-associated GTPase 1

1

0

High-throughput

0.458

High

1413857

DHRS4
Dehydrogenase/reductase SDR family member 4

1

0

High-throughput

0.458

High

1415716

TR61B
tRNA

1

0

High-throughput

0.458

High

1416586

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1417453

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.458

High

1418940

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1420437

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

1432335

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1433760

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.458

High

1435840

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1436145

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1436179

NT5D2
5'-nucleotidase domain-containing protein 2

1

0

High-throughput

0.458

High

1436423

CQ10B
Coenzyme Q-binding protein COQ10 homolog B, mitochondrial

1

0

High-throughput

0.458

High

1437496

SUCHY
Succinyl-CoA:glutarate CoA-transferase

1

0

High-throughput

0.458

High

1438365

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

1446284

NGRN
Neugrin

1

0

High-throughput

0.458

High

1447128

XPP3
Xaa-Pro aminopeptidase 3

1

0

High-throughput

0.458

High

1449729

LYRM2
LYR motif-containing protein 2

1

0

High-throughput

0.458

High

1450471

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1451327

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

1451363

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.458

High

1451473

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1451759

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.458

High

1453712

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.458

High

1454403

PAK5
Serine/threonine-protein kinase PAK 5

1

0

High-throughput

0.458

High

1458475

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

0

Small-scale

0.458

High

1458832

ZMYM2
Zinc finger MYM-type protein 2

1

0

High-throughput

0.458

High

1490905

COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

1

0

High-throughput

0.458

High

1490907

COQ4
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial

1

0

High-throughput

0.458

High

1490908

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

1047785

NOTC2
Neurogenic locus notch homolog protein 2

1

1

High-throughput

0.445

High

1135955

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

2

Small-scale

0.445

High

58752

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

5

High-throughput

0.437

High

158012

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.437

High

1224939

TENS2
Tensin-2

1

2

High-throughput

0.437

High

1256181

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1327287

FBXL6
F-box/LRR-repeat protein 6

1

1

High-throughput

0.437

High

1434281

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1460077

ZNHI2
Zinc finger HIT domain-containing protein 2

1

1

High-throughput

0.437

High

430537

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

1350669

ALAT2
Alanine aminotransferase 2

1

0

High-throughput

0.426

High

907232

SPHM
N-sulphoglucosamine sulphohydrolase

1

7

High-throughput

0.407

High

1235043

PKHA7
Pleckstrin homology domain-containing family A member 7

1

3

High-throughput

0.407

High

1247435

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.316

High

1447139

DAAF6
Dynein axonemal assembly factor 6

2

0

High-throughput

0.316

High

249217

DSCAM
Cell adhesion molecule DSCAM

1

0

High-throughput

0.282

High

599140

CBPE
Carboxypeptidase E

1

0

High-throughput

0.282

High

1098692

SBP1
Methanethiol oxidase

1

0

High-throughput

0.282

High

652689

GNLY
Granulysin

1

0

High-throughput

0.279

Low

656033

CAH6
Carbonic anhydrase 6

1

0

High-throughput

0.279

Low

1384161

ARRD3
Arrestin domain-containing protein 3

1

0

High-throughput

0.279

Low

1416483

LS14B
Protein LSM14 homolog B

1

0

High-throughput

0.279

Low

1452237

ST32B
Serine/threonine-protein kinase 32B

1

0

High-throughput

0.279

Low

1153146

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

High-throughput

0.265

Low

294556

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

699275

CALX
Calnexin

1

0

High-throughput

0.249

Low

769564

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1015923

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.249

Low

1312093

DJC10
DnaJ homolog subfamily C member 10

1

0

High-throughput

0.249

Low

1452437

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

0

High-throughput

0.249

Low

1490906

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

317484

GFPT2
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2

1

0

High-throughput

0.232

Low

1251209

ZNT10
Calcium/manganese antiporter SLC30A10

1

0

High-throughput

0.232

Low

1309581

F219A
Protein FAM219A

1

0

High-throughput

0.232

Low

1313883

S15A3
Solute carrier family 15 member 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025