HitPredict

Interactor 1: OCLN (Q16625)
Occludin
Gene: OCLN

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	34079125, 28877994
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030054 - cell junction
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 522 Hs			1 1121
+	Hs
		1084192 OCLN_HUMAN (1-522): 0: 757: 100.00		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		876397 OCLN_HUMAN (1-522): 0: 757: 100.00		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		1084184 OCLN_HUMAN (1-522): 0: 757: 100.00		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1084144 OCLN_HUMAN (1-522): 0: 757: 100.00		NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47
+	Hs
		1084139 OCLN_HUMAN (1-522): 0: 757: 100.00		ITCH_HUMAN (40-305): 7.41e-17: 88.1: 14.49
+	Hs
		808142 OCLN_HUMAN (1-522): 0: 757: 100.00		NEDD4_HUMAN (11-95): 1.03e-15: 84.6: 24.17
+	Rn
		1140971 OCLN_RAT (1-522): 0: 747: 87.57		Q5YB86_RAT (40-305): 1.34e-15: 83.9: 14.64
+	Hs
		1233832 MALD2_HUMAN (6-519): 7.84e-159: 465: 20.44		ITCH_HUMAN (40-305): 7.41e-17: 88.1: 14.49