HitPredict

Interactor 1: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Interactor 2: LC7L2 (Q9Y383)
Putative RNA-binding protein Luc7-like 2
Gene: LUC7L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.717

Property	Details
Experiments	26186194, 25416956, 32296183, 31515488, unassigned1304
Identification Methods	affinity chromatography technology, two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0016607 - nuclear speck
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 238 Hs			1 392
+	Hs
		1263481 SRS12_HUMAN (1-218): 8.5e-28: 108: 32.60		LC7L2_HUMAN (1-392): 1.49e-78: 249: 100.00
+	Hs
		1259886 PPIL4_HUMAN (1-84): 1.75e-25: 105: 26.97		LC7L2_HUMAN (1-392): 1.49e-78: 249: 100.00
+	Hs
		1084423 SRSF7_HUMAN (1-238): 6.03e-28: 108: 100.00		LUC7L_HUMAN (1-367): 3.39e-77: 244: 66.49
+	Hs
		1031502 PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00		LC7L2_HUMAN (1-392): 1.49e-78: 249: 100.00
+	Hs
		993004 SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65		LC7L2_HUMAN (1-392): 1.49e-78: 249: 100.00
+	Hs
		992951 SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65		LUC7L_HUMAN (1-367): 3.39e-77: 244: 66.49
+	Hs
		1329991 PABP3_HUMAN (6-192): 4.81e-18: 84.4: 14.74		LC7L2_HUMAN (1-392): 1.49e-78: 249: 100.00
+	Dm
		1359180 SRSF7_DROME (5-236): 3.77e-22: 93.4: 39.06		LUC7L_DROME (1-331): 7.22e-73: 235: 54.52
+	Sc
		376945 PABP_YEAST (7-95): 4.44e-17: 81.7: 22.34		LUC7_YEAST (5-248): 2.16e-65: 210: 30.95
+	Hs
		308193 SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65		LC7L3_HUMAN (8-389): 5.72e-58: 196: 28.51
+	Dm
		970879 RBP1_DROME (1-80): 1.02e-29: 109: 67.50		Q9W3X8_DROME (165-279): 2.1e-18: 88.4: 20.00