Protein: REC8
Meiotic recombination protein REC8 homolog (Cohesin Rec8p)

Gene: REC8
Organism: Homo sapiens
Interactions: 47
UniProt ID: O95072

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0000776 - kinetochore
GO:0000800 - lateral element
GO:0001556 - oocyte maturation
GO:0001673 - male germ cell nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

326169

SMC3
Structural maintenance of chromosomes protein 3

3

4

Small-scale

0.861

High

326147

SMC1A
Structural maintenance of chromosomes protein 1A

2

4

High-throughput

0.811

High

238331

RAD21
Double-strand-break repair protein rad21 homolog

1

1

High-throughput

0.691

High

326155

SMC1B
Structural maintenance of chromosomes protein 1B

1

4

Small-scale

0.618

High

326167

CHIP
E3 ubiquitin-protein ligase CHIP

2

1

High-throughput

0.611

High

326154

STAG2
Cohesin subunit SA-2

1

1

High-throughput

0.536

High

274416

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.513

High

326132

CCNA2
Cyclin-A2

1

0

High-throughput

0.513

High

326133

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

0

High-throughput

0.513

High

326134

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.513

High

326136

HS71L
Heat shock 70 kDa protein 1-like

1

0

High-throughput

0.513

High

326137

PRS7
26S proteasome regulatory subunit 7

1

0

High-throughput

0.513

High

326139

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.513

High

326140

PCBP3
Poly(rC)-binding protein 3

1

0

High-throughput

0.513

High

326145

SKP2
S-phase kinase-associated protein 2

1

0

High-throughput

0.513

High

326149

TBB8
Tubulin beta-8 chain

1

0

High-throughput

0.513

High

326156

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

0

High-throughput

0.513

High

326161

ESRP2
Epithelial splicing regulatory protein 2

1

0

High-throughput

0.513

High

326163

SYF1
Pre-mRNA-splicing factor SYF1

1

0

High-throughput

0.513

High

326164

CFDP1
Craniofacial development protein 1

1

0

High-throughput

0.513

High

326165

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.513

High

326166

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

0

High-throughput

0.513

High

326168

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

0

High-throughput

0.513

High

326170

MAGD1
Melanoma-associated antigen D1

1

0

High-throughput

0.513

High

226645

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

2

High-throughput

0.479

High

326135

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

326138

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

326141

MLF1
Myeloid leukemia factor 1

1

1

High-throughput

0.479

High

326148

MLF2
Myeloid leukemia factor 2

1

1

High-throughput

0.479

High

187430

FANCA
Fanconi anemia group A protein

1

0

Small-scale

0.458

High

326131

H2B1J
Histone H2B type 1-J

1

0

High-throughput

0.458

High

326143

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.458

High

326144

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.458

High

326153

SYCP3
Synaptonemal complex protein 3

1

0

Small-scale

0.458

High

326159

AASD1
Alanyl-tRNA editing protein Aarsd1

1

0

High-throughput

0.458

High

326162

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

326157

Q96BE0
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.437

High

326146

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

0

High-throughput

0.426

High

326130

BAG2
BAG family molecular chaperone regulator 2

2

0

High-throughput

0.318

High

124179

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.279

Low

177501

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.279

Low

326142

CKS1
Cyclin-dependent kinases regulatory subunit 1

1

0

High-throughput

0.279

Low

326150

GPAT2
Glycerol-3-phosphate acyltransferase 2, mitochondrial

1

0

High-throughput

0.279

Low

326160

CLPB
Mitochondrial disaggregase

1

0

High-throughput

0.279

Low

326151

MAVS
Mitochondrial antiviral-signaling protein

1

0

Small-scale

0.249

Low

326152

STING
Stimulator of interferon genes protein

1

0

Small-scale

0.249

Low

326158

RNF5
E3 ubiquitin-protein ligase RNF5

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025