HitPredict

Interactor 1: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Interactor 2: ATX2L (Q8WWM7)
Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein)
Gene: ATXN2L

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0016020 - membrane GO:0016607 - nuclear speck
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 1075
+	Hs
		1235753 CPSF7_HUMAN (1-525): 3.55e-48: 175: 40.82		ATX2L_HUMAN (1-1075): 6.36e-139: 447: 100.00
+	Hs
		1031402 PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51		ATX2L_HUMAN (1-1075): 6.36e-139: 447: 100.00
+	Hs
		516606 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		ATX2L_HUMAN (1-1075): 6.36e-139: 447: 100.00
+	Hs
		1056844 CPSF6_HUMAN (1-520): 3.7e-92: 294: 100.00		MDC1_HUMAN (4-779): 4.69e-18: 92.3: 9.29
+	Hs
		847103 SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98		CHD7_HUMAN (306-840): 4.88e-17: 89.3: 10.22
+	At
		1277466 PABP8_ARATH (82-173): 6.27e-09: 60.7: 22.83		CID4_ARATH (76-635): 3.2e-41: 163: 16.28
+	Hs
		1031438 PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51		ATX2_HUMAN (176-847): 3.45e-11: 70: 10.82
+	Sc
		376873 PABP_YEAST (82-174): 3.01e-12: 71.1: 27.96		PBP1_YEAST (86-726): 2.04e-27: 121: 16.04
+	Hs
		302269 SC31A_HUMAN (127-488): 4.72e-28: 121: 14.25		SC24C_HUMAN (613-1018): 1.53e-10: 67.5: 11.79
+	Mm
		1351630 PCLO_MOUSE (195-468): 6.01e-14: 77.6: 11.31		PCLO_MOUSE (5-1000): 4.6e-21: 102: 9.82
+	Hs
		516661 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		ATX2_HUMAN (176-847): 3.45e-11: 70: 10.82
+	Hs
		516595 PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40		KMT2C_HUMAN (325-862): 6.44e-10: 66.1: 10.78
+	Dm
		597063 PABP_DROME (81-169): 1.2e-18: 91.5: 24.44		ATX2_DROME (328-914): 5.77e-09: 62.6: 8.86
+	Hs
		1056974 WDR33_HUMAN (180-396): 5.21e-09: 61.5: 24.69		MDC1_HUMAN (4-779): 4.69e-18: 92.3: 9.29
+	Mm
		57185 SMCA4_MOUSE (172-423): 2.26e-10: 65.7: 12.30		CHD7_MOUSE (306-827): 2.78e-14: 80.3: 10.31
+	Dm
		113976 M9PB30_DROME (190-412): 1.36e-12: 73: 16.67		M9PB30_DROME (6-698): 8.12e-11: 68.8: 8.51
+	Hs
		867103 TGO1_HUMAN (138-380): 8.27e-13: 73.8: 25.18		SC24C_HUMAN (613-1018): 1.53e-10: 67.5: 11.79