Protein: RL11A
Large ribosomal subunit protein uL5A (60S ribosomal protein L11-A) (L16) (RP39) (YL22)

Gene: RL11A, RPL11A
Organism: Saccharomyces cerevisiae S288C
Interactions: 150
UniProt ID: P0C0W9

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0002181 - cytoplasmic translation
GO:0003723 - RNA binding
GO:0003735 - structural constituent of ribosome
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

503362

RL5
Large ribosomal subunit protein uL18

3

2

Small-scale

0.834

High

503331

RL11A
Large ribosomal subunit protein uL5A

2

1

High-throughput

0.754

High

503376

RPF2
Ribosome biogenesis protein RPF2

5

2

Small-scale

0.726

High

503381

ENP1
Essential nuclear protein 1

4

0

Small-scale

0.653

High

392059

HSP82
ATP-dependent molecular chaperone HSP82

3

2

High-throughput

0.640

High

503346

HSP71
Heat shock protein SSA1

3

1

High-throughput

0.633

High

503447

RRS1
Regulator of ribosome biosynthesis

3

2

Small-scale

0.630

High

503353

EF3A
Elongation factor 3A

1

1

High-throughput

0.618

High

503456

RL11B
Large ribosomal subunit protein uL5B

1

1

High-throughput

0.618

High

503361

KRR1
KRR1 small subunit processome component

2

2

Small-scale

0.611

High

503385

SSZ1
Ribosome-associated complex subunit SSZ1

2

1

High-throughput

0.611

High

503408

LSG1
Large subunit GTPase 1

2

7

High-throughput

0.611

High

503432

SXM1
Importin beta SMX1

2

2

Small-scale

0.611

High

433364

RL26A
Large ribosomal subunit protein uL24A

2

5

High-throughput

0.584

High

503336

RL44B
Large ribosomal subunit protein eL42B

2

2

High-throughput

0.584

High

503363

RL16A
Large ribosomal subunit protein uL13A

2

4

High-throughput

0.584

High

503378

GBLP
Small ribosomal subunit protein RACK1

2

6

Small-scale

0.584

High

503410

PESC
Pescadillo homolog

2

1

Small-scale

0.584

High

503413

NOG2
Nucleolar GTP-binding protein 2

2

7

Small-scale

0.584

High

503424

RS15
Small ribosomal subunit protein uS19

2

3

High-throughput

0.584

High

503448

TMA46
Translation machinery-associated protein 46

2

2

High-throughput

0.584

High

503352

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

Small-scale

0.559

High

503370

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

2

High-throughput

0.536

High

503379

HEK2
Heterogeneous nuclear rnp K-like protein 2

1

4

High-throughput

0.536

High

503391

NUG1
Nuclear GTP-binding protein NUG1

1

7

High-throughput

0.536

High

503398

NOP2
25S rRNA

1

3

High-throughput

0.536

High

503412

BRE5
UBP3-associated protein BRE5

1

4

High-throughput

0.536

High

503416

NOP13
Nucleolar protein 13

1

2

High-throughput

0.536

High

503423

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

503428

NOG1
Nucleolar GTP-binding protein 1

1

2

High-throughput

0.536

High

503440

SYO1
Synchronized import protein 1

1

0

Small-scale

0.529

High

503359

SIS1
Protein SIS1

1

3

High-throughput

0.515

High

503374

AP1B1
AP-1 complex subunit beta-1

1

0

High-throughput

0.513

High

503345

SSBP1
Single-stranded nucleic acid-binding protein

1

2

High-throughput

0.501

High

503442

SDO1
Ribosome maturation protein SDO1

1

1

Small-scale

0.501

High

503452

SMT3
Ubiquitin-like protein SMT3

1

1

High-throughput

0.481

High

149505

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

154111

RL36B
Large ribosomal subunit protein eL36B

1

2

High-throughput

0.479

High

383054

RLA4
Large ribosomal subunit protein P2B

1

3

High-throughput

0.479

High

409659

RL24A
Large ribosomal subunit protein eL24A

1

4

High-throughput

0.479

High

409856

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.479

High

414972

RL39
Large ribosomal subunit protein eL39

1

3

High-throughput

0.479

High

427520

RLA1
Large ribosomal subunit protein P1A

1

3

High-throughput

0.479

High

432444

RL7A
Large ribosomal subunit protein uL30A

1

6

High-throughput

0.479

High

432950

RL6B
Large ribosomal subunit protein eL6B

1

4

High-throughput

0.479

High

434483

RL22A
Large ribosomal subunit protein eL22A

1

4

High-throughput

0.479

High

434716

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

435688

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

436268

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

5

High-throughput

0.479

High

438569

SC160
Protein SCP160

1

3

High-throughput

0.479

High

441624

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.479

High

454368

PHO4
Phosphate system positive regulatory protein PHO4

1

1

High-throughput

0.479

High

454788

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.479

High

502766

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.479

High

503332

RL27B
Large ribosomal subunit protein eL27B

1

2

High-throughput

0.479

High

503333

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.479

High

503334

RL20B
Large ribosomal subunit protein eL20B

1

2

High-throughput

0.479

High

503335

RL43B
Large ribosomal subunit protein eL43B

1

2

High-throughput

0.479

High

503337

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.479

High

503338

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.479

High

503339

RL2A
Large ribosomal subunit protein uL2A

1

3

High-throughput

0.479

High

503340

RL18B
Large ribosomal subunit protein eL18B

1

2

High-throughput

0.479

High

503341

RL12B
Large ribosomal subunit protein uL11B

1

2

High-throughput

0.479

High

503342

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

503343

RL19B
Large ribosomal subunit protein eL19

1

3

High-throughput

0.479

High

503344

RL35A
Large ribosomal subunit protein uL29A

1

2

High-throughput

0.479

High

503347

RLA3
Large ribosomal subunit protein P1B

1

3

High-throughput

0.479

High

503350

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

503351

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.479

High

503354

RL8A
Large ribosomal subunit protein eL8A

1

3

High-throughput

0.479

High

503355

SNF2
Transcription regulatory protein SNF2

1

6

High-throughput

0.479

High

503358

RL24B
Large ribosomal subunit protein eL24B

1

4

High-throughput

0.479

High

503360

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

503364

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

503367

RL8B
Large ribosomal subunit protein eL8B

1

3

High-throughput

0.479

High

503368

HOG1
Mitogen-activated protein kinase HOG1

1

1

High-throughput

0.479

High

503369

ZUO1
Zuotin

1

5

High-throughput

0.479

High

503371

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

503372

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.479

High

503373

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

503375

RL14A
Large ribosomal subunit protein eL14A

1

3

High-throughput

0.479

High

503383

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

503384

RL14B
Large ribosomal subunit protein eL14B

1

3

High-throughput

0.479

High

503387

NMD3
60S ribosomal export protein NMD3

1

1

High-throughput

0.479

High

503389

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

503390

NOC2
Nucleolar complex protein 2

1

1

Small-scale

0.479

High

503393

RL13B
Large ribosomal subunit protein eL13B

1

3

High-throughput

0.479

High

503395

RL34B
Large ribosomal subunit protein eL34B

1

4

High-throughput

0.479

High

503397

RLP7
Ribosome biogenesis protein RLP7

1

6

High-throughput

0.479

High

503399

RL33B
Large ribosomal subunit protein eL33B

1

1

High-throughput

0.479

High

503402

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.479

High

503404

RL37A
Large ribosomal subunit protein eL37A

1

2

High-throughput

0.479

High

503405

RL4B
Large ribosomal subunit protein uL4B

1

2

High-throughput

0.479

High

503406

RL37B
Large ribosomal subunit protein eL37B

1

2

High-throughput

0.479

High

503407

VID30
GID complex subunit 1

1

2

High-throughput

0.479

High

503409

RL26B
Large ribosomal subunit protein uL24B

1

5

High-throughput

0.479

High

503418

NOP15
Ribosome biogenesis protein 15

1

2

High-throughput

0.479

High

503419

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.479

High

503420

ORC1
Origin recognition complex subunit 1

1

2

High-throughput

0.479

High

503421

RL22B
Large ribosomal subunit protein eL22B

1

4

High-throughput

0.479

High

503422

RL34A
Large ribosomal subunit protein eL34A

1

4

High-throughput

0.479

High

503425

RL6A
Large ribosomal subunit protein eL6A

1

4

High-throughput

0.479

High

503426

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

1

High-throughput

0.479

High

503427

RL21A
Large ribosomal subunit protein eL21A

1

3

High-throughput

0.479

High

503429

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.479

High

503433

DHR1
Probable ATP-dependent RNA helicase DHR1

1

3

High-throughput

0.479

High

503434

PUF6
Pumilio homology domain family member 6

1

2

High-throughput

0.479

High

503438

NOC4
Nucleolar complex protein 4

1

4

High-throughput

0.479

High

503446

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

503451

RL7B
Large ribosomal subunit protein uL30B

1

6

High-throughput

0.479

High

503453

DBP10
ATP-dependent RNA helicase DBP10

1

5

High-throughput

0.479

High

503454

RL21B
Large ribosomal subunit protein eL21B

1

3

High-throughput

0.479

High

503455

RL13A
Large ribosomal subunit protein eL13A

1

3

High-throughput

0.479

High

383436

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

401828

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

434212

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.458

High

503357

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.458

High

503380

GID4
GID complex substrate-recognition subunit 4

1

0

High-throughput

0.458

High

503388

RIX1
Pre-rRNA-processing protein RIX1

1

0

Small-scale

0.458

High

503400

REF2
RNA end formation protein 2

1

0

High-throughput

0.458

High

503403

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

503436

LTN1
E3 ubiquitin-protein ligase listerin

1

0

Small-scale

0.458

High

503439

ELP1
Elongator complex protein 1

1

0

High-throughput

0.458

High

503449

KAD6
Adenylate kinase isoenzyme 6 homolog FAP7

1

0

Small-scale

0.458

High

503348

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

503366

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.445

High

503392

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

503401

ALB1
Ribosome biogenesis protein ALB1

1

1

Small-scale

0.445

High

503415

JJJ1
J protein JJJ1

1

2

High-throughput

0.445

High

503430

GCN5
Histone acetyltransferase GCN5

1

3

High-throughput

0.445

High

503431

ARX1
Probable metalloprotease ARX1

1

3

Small-scale

0.445

High

503443

BUD20
Bud site selection protein 20

1

1

Small-scale

0.445

High

503450

NOP53
Ribosome biogenesis protein NOP53

1

2

Small-scale

0.445

High

503417

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

503349

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.437

High

503356

KCC2
Calcium/calmodulin-dependent protein kinase II

1

1

High-throughput

0.437

High

503377

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.437

High

503382

YB8A
Putative uncharacterized protein YBR285W

1

1

Small-scale

0.437

High

503411

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

2

Small-scale

0.437

High

503414

GIS2
Zinc finger protein GIS2

1

4

High-throughput

0.437

High

503435

POB3
FACT complex subunit POB3

1

1

High-throughput

0.437

High

503441

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.437

High

503365

BUD14
Bud site selection protein 14

1

0

High-throughput

0.426

High

503445

SYC1
Protein SYC1

1

0

High-throughput

0.426

High

503386

RPF1
Ribosome production factor 1

1

2

High-throughput

0.407

High

503394

TM108
Protein TMA108

1

0

High-throughput

0.249

Low

503396

SNL1
HSP70 co-chaperone SNL1

1

0

Small-scale

0.249

Low

503437

RQC1
Ribosome quality control complex subunit 1

1

0

Small-scale

0.249

Low

503444

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025