HitPredict

Interactor 1: DREB (Q16643)
Drebrin (Developmentally-regulated brain protein)
Gene: DBN1

Interactor 2: HOME1 (Q86YM7)
Homer protein homolog 1 (Homer-1)
Gene: HOMER1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	26496610, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0014069 - postsynaptic density GO:0030425 - dendrite GO:0098978 - glutamatergic synapse GO:0099524 - postsynaptic cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 649 Hs			1 354
+	Hs
		1085077 DREB_HUMAN (1-649): 5.59e-95: 307: 100.00		HOME3_HUMAN (3-354): 3.77e-60: 199: 49.72
+	Hs
		1085076 DREB_HUMAN (1-649): 5.59e-95: 307: 100.00		HOME2_HUMAN (1-351): 8.57e-56: 187: 51.00
+	Hs
		1205738 DBNL_HUMAN (3-464): 1.68e-73: 244: 29.98		HOME1_HUMAN (1-354): 4.46e-62: 204: 100.00
+	Hs
		787923 DREB_HUMAN (1-649): 5.59e-95: 307: 100.00		EPS15_HUMAN (92-321): 5.03e-30: 123: 11.97
+	Hs
		840483 DREB_HUMAN (1-649): 5.59e-95: 307: 100.00		VASP_HUMAN (1-146): 3.19e-28: 115: 22.36
+	Hs
		1025404 DREB_HUMAN (1-649): 5.59e-95: 307: 100.00		CACO2_HUMAN (116-340): 1.19e-25: 108: 17.70
+	Rn
		1126747 SYNJ1_RAT (126-647): 6.09e-42: 165: 11.09		Q5JC29_RAT (65-332): 2.93e-28: 117: 12.69
+	Hs
		203214 SYNJ1_HUMAN (103-518): 1.79e-09: 63.3: 9.35		VASP_HUMAN (1-146): 3.19e-28: 115: 22.36
+	Hs
		551790 TITIN_HUMAN (148-594): 2.68e-10: 66.3: 11.55		DESP_HUMAN (95-342): 9.29e-09: 59.3: 12.30