Protein: CAF1A
Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (CAF-1 90 kDa subunit) (Chromatin assembly factor 1 subunit p90) (RAP1 localization factor 2)

Gene: CAF1A, RLF2
Organism: Saccharomyces cerevisiae S288C
Interactions: 196
UniProt ID: Q12495

Gene Ontology (top 5):
GO:0000775 - chromosome, centromeric region
GO:0000785 - chromatin
GO:0000786 - nucleosome
GO:0005634 - nucleus
GO:0006260 - DNA replication

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

567737

MSI1
Histone-binding protein MSI1

15

13

Small-scale

0.981

High

963813

H3
Histone H3

9

13

Small-scale

0.964

High

382430

H4
Histone H4

6

5

Small-scale

0.933

High

1045184

CAF1B
Chromatin assembly factor 1 subunit B

12

11

Small-scale

0.755

High

586499

PCNA
Proliferating cell nuclear antigen

7

3

Small-scale

0.744

High

364830

CDK1
Cyclin-dependent kinase 1

2

4

Small-scale

0.629

High

815673

LIS1
Nuclear distribution protein PAC1

1

9

High-throughput

0.621

High

924265

IPI3
Pre-rRNA-processing protein IPI3

1

9

High-throughput

0.621

High

779389

CENPA
Histone H3-like centromeric protein CSE4

1

13

Small-scale

0.618

High

440988

CDC7
Cell division control protein 7

2

10

Small-scale

0.602

High

1053890

IMB1
Importin subunit beta-1

2

1

High-throughput

0.601

High

829879

SAS2
Histone acetyltransferase SAS2

1

3

Small-scale

0.594

High

736762

ASF1
Histone chaperone ASF1

2

5

Small-scale

0.585

High

898179

ORC5
Origin recognition complex subunit 5

2

0

Small-scale

0.583

High

932321

ORC3
Origin recognition complex subunit 3

2

0

Small-scale

0.583

High

1084991

CAF1A
Chromatin assembly factor 1 subunit A

2

10

High-throughput

0.576

High

1039083

IMA1
Importin subunit alpha

2

0

High-throughput

0.576

High

381678

H2B2
Histone H2B.2

1

4

High-throughput

0.575

High

419919

H2A2
Histone H2A.2

1

4

High-throughput

0.575

High

794022

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

10

High-throughput

0.575

High

816153

HAT2
Histone acetyltransferase type B subunit 2

1

16

High-throughput

0.575

High

1084992

CMR1
DNA damage-binding protein CMR1

1

8

High-throughput

0.575

High

1084993

H2AZ
Histone H2A.Z

1

3

High-throughput

0.575

High

708620

TF2B
Transcription initiation factor IIB

2

3

High-throughput

0.571

High

639871

SIR1
Regulatory protein SIR1

1

0

Small-scale

0.561

High

1044880

SAS4
Something about silencing protein 4

1

0

Small-scale

0.561

High

820453

RT106
Histone chaperone RTT106

2

0

Small-scale

0.560

High

805537

ORC6
Origin recognition complex subunit 6

1

0

Small-scale

0.518

High

1084995

SAS5
Something about silencing protein 5

1

3

Small-scale

0.508

High

594654

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

671278

SIS1
Protein SIS1

1

2

High-throughput

0.479

High

548251

BIK1
Nuclear fusion protein BIK1

1

5

High-throughput

0.470

High

1064510

SLK19
Kinetochore protein SLK19

1

3

High-throughput

0.470

High

557793

SRS2
ATP-dependent DNA helicase SRS2

1

0

Small-scale

0.460

High

602152

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.460

High

636482

ACE2
Metallothionein expression activator

1

0

High-throughput

0.460

High

763760

CENPC
Inner kinetochore subunit MIF2

1

0

High-throughput

0.460

High

816074

ACA1
ATF/CREB activator 1

1

0

High-throughput

0.460

High

817048

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.460

High

844499

GZF3
Protein GZF3

1

0

High-throughput

0.460

High

1038179

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.460

High

1044408

YAP6
AP-1-like transcription factor YAP6

1

0

High-throughput

0.460

High

1046887

APC4
Anaphase-promoting complex subunit 4

1

0

High-throughput

0.460

High

673138

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.458

High

764046

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

1084474

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

865121

TCPQ
T-complex protein 1 subunit theta

1

1

High-throughput

0.457

High

444807

SIR2
NAD-dependent histone deacetylase SIR2

1

2

High-throughput

0.445

High

525653

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

528104

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

546873

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

614858

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

1

9

High-throughput

0.445

High

623041

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.445

High

643680

SNF2
Transcription regulatory protein SNF2

1

15

High-throughput

0.445

High

664480

MCM3
DNA replication licensing factor MCM3

1

5

High-throughput

0.445

High

672036

MSH3
DNA mismatch repair protein MSH3

1

5

High-throughput

0.445

High

678356

RSC6
Chromatin structure-remodeling complex protein RSC6

1

3

High-throughput

0.445

High

682950

MSH2
DNA mismatch repair protein MSH2

1

5

High-throughput

0.445

High

708807

TF3B
Transcription factor IIIB 70 kDa subunit

1

3

High-throughput

0.445

High

713064

MCM2
DNA replication licensing factor MCM2

1

6

High-throughput

0.445

High

713319

MCM5
Minichromosome maintenance protein 5

1

6

High-throughput

0.445

High

734503

BTAF1
TATA-binding protein-associated factor MOT1

1

16

High-throughput

0.445

High

737658

HIR1
Protein HIR1

1

13

High-throughput

0.445

High

737687

HIR2
Protein HIR2

1

10

High-throughput

0.445

High

739833

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.445

High

742750

HSP7F
Heat shock protein homolog SSE1

1

12

High-throughput

0.445

High

743062

SWI3
SWI/SNF complex subunit SWI3

1

5

High-throughput

0.445

High

743157

STH1
Nuclear protein STH1/NPS1

1

12

High-throughput

0.445

High

744365

CHD1
Chromo domain-containing protein 1

1

12

High-throughput

0.445

High

745634

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

1

High-throughput

0.445

High

745676

ORC2
Origin recognition complex subunit 2

1

1

High-throughput

0.445

High

746776

PDC2
Protein PDC2

1

2

High-throughput

0.445

High

751915

TFC4
Transcription factor tau 131 kDa subunit

1

3

High-throughput

0.445

High

763405

TAF14
Transcription initiation factor TFIID subunit 14

1

3

High-throughput

0.445

High

777144

BDF1
Bromodomain-containing factor 1

1

8

High-throughput

0.445

High

794245

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

14

High-throughput

0.445

High

798132

SWC5
SWR1-complex protein 5

1

2

High-throughput

0.445

High

804014

RSC30
Chromatin structure-remodeling complex protein RSC30

1

1

High-throughput

0.445

High

805242

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

2

High-throughput

0.445

High

823066

ATAD2
ATPase histone chaperone YTA7

1

3

High-throughput

0.445

High

849635

SWP82
SWI/SNF global transcription activator complex subunit SWP82

1

1

High-throughput

0.445

High

850607

RSC8
Chromatin structure-remodeling complex protein RSC8

1

3

High-throughput

0.445

High

917082

MCM6
DNA replication licensing factor MCM6

1

5

High-throughput

0.445

High

917342

INO80
Chromatin-remodeling ATPase INO80

1

12

High-throughput

0.445

High

917409

ITC1
Imitation switch two complex protein 1

1

1

High-throughput

0.445

High

918535

RSC1
Chromatin structure-remodeling complex subunit RSC1

1

12

High-throughput

0.445

High

922155

SNF12
Transcription regulatory protein SNF12

1

3

High-throughput

0.445

High

924913

AF9
Protein AF-9 homolog

1

3

High-throughput

0.445

High

925255

ARP5
Actin-related protein 5

1

6

High-throughput

0.445

High

932261

ORC1
Origin recognition complex subunit 1

1

3

High-throughput

0.445

High

932332

ORC4
Origin recognition complex subunit 4

1

1

High-throughput

0.445

High

1010225

ARP4
Actin-related protein 4

1

9

High-throughput

0.445

High

1025787

RAD25
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2

1

1

High-throughput

0.445

High

1030350

HPC2
Histone promoter control protein 2

1

3

High-throughput

0.445

High

1035360

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

10

High-throughput

0.445

High

1042821

NHP10
Non-histone protein 10

1

4

High-throughput

0.445

High

1043994

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

2

High-throughput

0.445

High

1044189

MSH6
DNA mismatch repair protein MSH6

1

5

High-throughput

0.445

High

1044521

RUVB1
RuvB-like protein 1

1

8

High-throughput

0.445

High

1048423

RCO1
Transcriptional regulatory protein RCO1

1

6

High-throughput

0.445

High

1050231

TRI1
Protein TRI1

1

2

High-throughput

0.445

High

1050606

ARP9
Actin-like protein ARP9

1

7

High-throughput

0.445

High

1054045

SFH1
Chromatin structure-remodeling complex subunit SFH1

1

1

High-throughput

0.445

High

1056361

RSC3
Chromatin structure-remodeling complex protein RSC3

1

1

High-throughput

0.445

High

1061940

ESC8
Protein ESC8

1

1

High-throughput

0.445

High

1064907

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

15

High-throughput

0.445

High

1084855

ARP8
Actin-like protein ARP8

1

6

High-throughput

0.445

High

1084888

ARP7
Actin-related protein 7

1

7

High-throughput

0.445

High

1084956

RUVB2
RuvB-like protein 2

1

8

High-throughput

0.445

High

654755

SPA2
Protein SPA2

1

3

High-throughput

0.439

High

735692

SMY1
Kinesin-related protein SMY1

1

6

High-throughput

0.439

High

779817

DYHC
Dynein heavy chain, cytoplasmic

1

2

High-throughput

0.439

High

792498

CDC27
Anaphase-promoting complex subunit CDC27

1

2

High-throughput

0.439

High

803317

ETP1
RING finger protein ETP1

1

1

High-throughput

0.439

High

806062

KEL1
Kelch repeat-containing protein 1

1

1

High-throughput

0.439

High

430950

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

5

High-throughput

0.437

High

149236

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.426

High

448482

RAD52
DNA repair and recombination protein RAD52

1

0

High-throughput

0.426

High

483815

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

0

High-throughput

0.426

High

550095

RAP1
DNA-binding protein RAP1

1

0

High-throughput

0.426

High

553569

PDR1
Transcription factor PDR1

1

0

High-throughput

0.426

High

561552

TBP
TATA-box-binding protein

1

0

High-throughput

0.426

High

626552

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.426

High

676688

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.426

High

744585

T2AG
Transcription initiation factor IIA subunit 2

1

0

High-throughput

0.426

High

744633

TFB1
General transcription and DNA repair factor IIH subunit TFB1

1

0

High-throughput

0.426

High

794855

CND2
Condensin complex subunit 2

1

0

High-throughput

0.426

High

816630

EAF5
Chromatin modification-related protein EAF5

1

0

High-throughput

0.426

High

817442

VHR2
Transcription factor VHR2

1

0

High-throughput

0.426

High

817718

IES5
Ino eighty subunit 5

1

0

High-throughput

0.426

High

849905

IES1
Ino eighty subunit 1

1

0

High-throughput

0.426

High

858428

SUM1
Suppressor of mar1-1 protein

1

0

High-throughput

0.426

High

866261

HIR3
Histone transcription regulator 3

1

0

High-throughput

0.426

High

893383

TAF4
Transcription initiation factor TFIID subunit 4

1

0

High-throughput

0.426

High

898205

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.426

High

916623

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

0

High-throughput

0.426

High

917883

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.426

High

918581

ENV11
Late endosome and vacuole interface protein 11

1

0

High-throughput

0.426

High

919147

YG36
Uncharacterized protein YGR126W

1

0

High-throughput

0.426

High

919704

RT102
Regulator of Ty1 transposition protein 102

1

0

High-throughput

0.426

High

921181

H1
Histone H1

1

0

High-throughput

0.426

High

1026875

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.426

High

1036952

TBF1
Protein TBF1

1

0

High-throughput

0.426

High

1040673

DIG1
Down-regulator of invasive growth 1

1

0

High-throughput

0.426

High

1041015

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

0

High-throughput

0.426

High

1046899

DPB4
DNA polymerase epsilon subunit D

1

0

High-throughput

0.426

High

1049098

YM91
Putative methyltransferase YMR310C

1

0

High-throughput

0.426

High

1050251

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.426

High

1054882

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.426

High

1056513

CND3
Condensin complex subunit 3

1

0

High-throughput

0.426

High

1061390

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

1064498

IES4
Ino eighty subunit 4

1

0

High-throughput

0.426

High

1084152

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

1

0

High-throughput

0.426

High

1084722

TAF3
Transcription initiation factor TFIID subunit 3

1

0

High-throughput

0.426

High

1084742

TFC8
Transcription factor tau 60 kDa subunit

1

0

High-throughput

0.426

High

1084802

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.426

High

1084810

IES3
Ino eighty subunit 3

1

0

High-throughput

0.426

High

1084895

TFC7
Transcription factor tau 55 kDa subunit

1

0

High-throughput

0.426

High

1084908

EAF3
Chromatin modification-related protein EAF3

1

0

High-throughput

0.426

High

510929

HSP77
Import motor subunit, mitochondrial

1

6

High-throughput

0.407

High

536194

ARF1
ADP-ribosylation factor 1

1

1

High-throughput

0.407

High

633586

SAR1
Small COPII coat GTPase SAR1

1

4

High-throughput

0.407

High

815082

SNF7
Vacuolar-sorting protein SNF7

1

2

High-throughput

0.407

High

836979

MPG1
Mannose-1-phosphate guanyltransferase

1

2

High-throughput

0.407

High

850392

IOC3
ISWI one complex protein 3

1

1

High-throughput

0.407

High

864351

NET1
Nucleolar protein NET1

1

1

High-throughput

0.407

High

1035377

TOF2
Topoisomerase 1-associated factor 2

1

1

High-throughput

0.407

High

1055394

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

11

High-throughput

0.407

High

1065644

YP204
Y' element ATP-dependent helicase YPR204W

1

2

High-throughput

0.407

High

1084086

TFB4
General transcription and DNA repair factor IIH subunit TFB4

1

1

High-throughput

0.407

High

1084772

HSP42
Heat shock protein 42

1

1

High-throughput

0.407

High

678913

CSM1
Monopolin complex subunit CSM1

2

0

High-throughput

0.300

High

758494

SEG2
Eisosome protein SEG2

1

0

High-throughput

0.251

Low

776768

YKF0
Uncharacterized protein YKL050C

1

0

High-throughput

0.251

Low

782957

JNM1
Nuclear migration protein JNM1

1

0

High-throughput

0.251

Low

797295

YSW1
Spore-specific protein YSW1

1

0

High-throughput

0.251

Low

864867

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.251

Low

917802

MPS2
Monopolar spindle protein 2

1

0

High-throughput

0.251

Low

924549

PGA2
Processing of GAS1 and ALP protein 2

1

0

High-throughput

0.251

Low

1040702

SVL3
Styryl dye vacuolar localization protein 3

1

0

High-throughput

0.251

Low

1050279

FAR8
Factor arrest protein 8

1

0

High-throughput

0.251

Low

1054080

FMP27
Protein FMP27, mitochondrial

1

0

High-throughput

0.251

Low

1055559

YP148
Uncharacterized protein YPR148C

1

0

High-throughput

0.251

Low

1084994

YH41A
Transposon Ty4-H Gag polyprotein

1

0

High-throughput

0.251

Low

807863

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

358385

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

586075

DPOG
DNA polymerase gamma

1

0

High-throughput

0.232

Low

737510

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.232

Low

781345

DID4
DOA4-independent degradation protein 4

1

0

High-throughput

0.232

Low

858499

TFC5
Transcription factor TFIIIB component B''

1

0

High-throughput

0.232

Low

863798

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

923813

IST1
Vacuolar protein sorting-associated protein IST1

1

0

High-throughput

0.232

Low

1053936

CND1
Condensin complex subunit 1

1

0

High-throughput

0.232

Low

1084228

IOC2
ISWI one complex protein 2

1

0

High-throughput

0.232

Low

1084565

RFM1
Repression factor of MSEs protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025