HitPredict

Interactor 1: PRSS8 (Q16651)
Prostasin (EC 3.4.21.-) (Channel-activating protease 1) (CAP1) (Serine protease 8) [Cleaved into: Prostasin light chain; Prostasin heavy chain]
Gene: PRSS8

Interactor 2: I27RA (Q6UWB1)
Interleukin-27 receptor subunit alpha (IL-27 receptor subunit alpha) (IL-27R subunit alpha) (IL-27R-alpha) (IL-27RA) (Cytokine receptor WSX-1) (Cytokine receptor-like 1) (Type I T-cell cytokine receptor) (TCCR) (ZcytoR1)
Gene: IL27RA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 343 Hs			1 636
+	Hs
		489982 TM11B_HUMAN (31-284): 2.83e-105: 316: 39.61		PTPRF_HUMAN (25-631): 1.03e-51: 195: 11.58
+	Hs
		1032026 TMPSD_HUMAN (37-310): 4.83e-104: 318: 37.91		PTPRS_HUMAN (14-631): 8.1e-48: 183: 10.80
+	Hs
		1032050 ST14_HUMAN (29-284): 3.53e-98: 310: 38.95		PTPRS_HUMAN (14-631): 8.1e-48: 183: 10.80
+	Hs
		1198227 TM11B_HUMAN (31-284): 2.83e-105: 316: 39.61		FND3A_HUMAN (232-635): 1.81e-31: 133: 10.72
+	Hs
		409573 HEPS_HUMAN (27-297): 2.7e-103: 311: 38.38		FND3A_HUMAN (232-635): 1.81e-31: 133: 10.72
+	Hs
		362698 TRY2_HUMAN (44-289): 1.45e-105: 311: 37.40		FINC_HUMAN (24-396): 8.68e-20: 96.5: 11.54
+	Hs
		770208 TMPSD_HUMAN (37-310): 4.83e-104: 318: 37.91		IL6RB_HUMAN (2-316): 7.71e-14: 76.9: 11.04
+	Hs
		770215 ST14_HUMAN (29-284): 3.53e-98: 310: 38.95		IL6RB_HUMAN (2-316): 7.71e-14: 76.9: 11.04