HitPredict

Interactor 1: NRF1 (Q16656)
Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal)
Gene: NRF1

Interactor 2: LHX4 (Q969G2)
LIM/homeobox protein Lhx4 (LIM homeobox protein 4)
Gene: LHX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	26871637
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 503 Hs			1 390
+	Hs
		1085288 NRF1_HUMAN (1-503): 0: 848: 100.00		LHX3_HUMAN (1-390): 1.94e-87: 271: 60.25
+	Hs
		3369 NRF1_HUMAN (1-503): 0: 848: 100.00		A0A0S2Z5S9_HUMAN (1-88): 2.21e-57: 184: 97.73
+	Hs
		1085291 NRF1_HUMAN (1-503): 0: 848: 100.00		LHX6_HUMAN (8-290): 1.23e-46: 165: 27.78
+	Hs
		903725 NRF1_HUMAN (1-503): 0: 848: 100.00		LMO4_HUMAN (29-150): 2.22e-31: 118: 43.31