Protein: VGFR1
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)

Gene: VGFR1, FLT1
Organism: Homo sapiens
Interactions: 170
UniProt ID: P17948

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0002548 - monocyte chemotaxis
GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0005021 - vascular endothelial growth factor receptor activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

549553

VEGFA
Vascular endothelial growth factor A, long form

12

20

Small-scale

0.980

High

572599

PLGF
Placenta growth factor

4

20

Small-scale

0.882

High

572600

VEGFB
Vascular endothelial growth factor B

2

18

Small-scale

0.812

High

572628

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

2

20

Small-scale

0.778

High

572588

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

20

Small-scale

0.775

High

572590

VGFR2
Vascular endothelial growth factor receptor 2

2

17

Small-scale

0.768

High

572619

SHC2
SHC-transforming protein 2

2

20

Small-scale

0.754

High

572674

SRPK1
SRSF protein kinase 1

1

18

High-throughput

0.735

High

572620

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

9

Small-scale

0.730

High

572581

VGFR1
Vascular endothelial growth factor receptor 1

1

17

Small-scale

0.692

High

572583

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

18

Small-scale

0.680

High

572596

CRKL
Crk-like protein

1

20

Small-scale

0.665

High

572586

CBL
E3 ubiquitin-protein ligase CBL

3

20

Small-scale

0.646

High

572589

SHC1
SHC-transforming protein 1

1

20

Small-scale

0.621

High

155265

NRP1
Neuropilin-1

1

12

Small-scale

0.618

High

411995

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.618

High

414724

CDK1
Cyclin-dependent kinase 1

1

8

High-throughput

0.618

High

433247

YES
Tyrosine-protein kinase Yes

1

20

Small-scale

0.618

High

572587

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

18

Small-scale

0.618

High

572592

STAT3
Signal transducer and activator of transcription 3

1

13

Small-scale

0.618

High

572603

DYN2
Dynamin-2

1

10

High-throughput

0.618

High

572678

OSBL8
Oxysterol-binding protein-related protein 8

1

4

High-throughput

0.618

High

416347

S10A9
Protein S100-A9

1

2

Small-scale

0.575

High

572664

ROBO4
Roundabout homolog 4

1

13

Small-scale

0.575

High

297718

MICA2
[F-actin]-monooxygenase MICAL2

1

9

Small-scale

0.553

High

572594

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

13

Small-scale

0.553

High

572597

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

11

High-throughput

0.536

High

486224

CCL3
C-C motif chemokine 3

1

3

High-throughput

0.536

High

572630

SG2A2
Mammaglobin-A

1

2

High-throughput

0.536

High

215103

LANC1
Glutathione S-transferase LANCL1

1

2

High-throughput

0.500

High

572662

CA054
Uncharacterized protein C1orf54

1

1

High-throughput

0.489

High

572698

FBX2
F-box only protein 2

1

7

High-throughput

0.489

High

208524

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

4

High-throughput

0.479

High

214497

MYO1B
Unconventional myosin-Ib

1

6

High-throughput

0.479

High

229302

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

7

High-throughput

0.479

High

311473

SMC2
Structural maintenance of chromosomes protein 2

1

11

High-throughput

0.479

High

351047

LDLR
Low-density lipoprotein receptor

1

3

Small-scale

0.479

High

376420

APOB
Apolipoprotein B-100

1

1

High-throughput

0.479

High

449182

LEG1
Galectin-1

1

6

Small-scale

0.479

High

451841

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

5

High-throughput

0.479

High

505333

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

1

High-throughput

0.479

High

531715

PDIA4
Protein disulfide-isomerase A4

1

11

High-throughput

0.479

High

571663

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

11

High-throughput

0.479

High

572582

ARF4
ADP-ribosylation factor 4

1

11

High-throughput

0.479

High

572585

RAB6A
Ras-related protein Rab-6A

1

7

High-throughput

0.479

High

572591

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

572593

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

7

High-throughput

0.479

High

572602

SERPH
Serpin H1

1

6

High-throughput

0.479

High

572605

BLM
RecQ-like DNA helicase BLM

1

4

High-throughput

0.479

High

572606

SYRC
Arginine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

572607

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

6

High-throughput

0.479

High

572608

PSA
Puromycin-sensitive aminopeptidase

1

2

High-throughput

0.479

High

572609

RBM11
Splicing regulator RBM11

1

2

High-throughput

0.479

High

572611

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

6

High-throughput

0.479

High

572614

ARF6
ADP-ribosylation factor 6

1

11

High-throughput

0.479

High

572616

RACK1
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.479

High

572617

PRKDC
DNA-dependent protein kinase catalytic subunit

1

8

High-throughput

0.479

High

572622

PURA
Transcriptional activator protein Pur-alpha

1

2

High-throughput

0.479

High

572623

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

11

High-throughput

0.479

High

572627

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

1

2

High-throughput

0.479

High

572629

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

3

High-throughput

0.479

High

572633

FHL3
Four and a half LIM domains protein 3

1

11

High-throughput

0.479

High

572634

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

3

High-throughput

0.479

High

572635

SMC1A
Structural maintenance of chromosomes protein 1A

1

12

High-throughput

0.479

High

572637

SYK
Lysine--tRNA ligase

1

5

High-throughput

0.479

High

572638

PCH2
Pachytene checkpoint protein 2 homolog

1

4

High-throughput

0.479

High

572639

Q4LE69
1-phosphatidylinositol 4-kinase

1

12

High-throughput

0.479

High

572643

RN213
E3 ubiquitin-protein ligase RNF213

1

1

High-throughput

0.479

High

572645

C1TM
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

1

3

High-throughput

0.479

High

572647

DHX30
ATP-dependent RNA helicase DHX30

1

7

High-throughput

0.479

High

572657

COQ8A
Atypical kinase COQ8A, mitochondrial

1

1

High-throughput

0.479

High

572659

DDX54
ATP-dependent RNA helicase DDX54

1

14

High-throughput

0.479

High

572663

DNJC9
DnaJ homolog subfamily C member 9

1

17

High-throughput

0.479

High

572668

ARHG2
Rho guanine nucleotide exchange factor 2

1

19

High-throughput

0.479

High

572669

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

4

High-throughput

0.479

High

572670

DDX27
Probable ATP-dependent RNA helicase DDX27

1

14

High-throughput

0.479

High

572679

DDX47
Probable ATP-dependent RNA helicase DDX47

1

9

High-throughput

0.479

High

572680

PDCL3
Phosducin-like protein 3

1

2

High-throughput

0.479

High

572681

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

7

High-throughput

0.479

High

572683

YTDC2
3'-5' RNA helicase YTHDC2

1

7

High-throughput

0.479

High

572688

MDN1
Midasin

1

8

High-throughput

0.479

High

572689

DD19A
ATP-dependent RNA helicase DDX19A

1

4

High-throughput

0.479

High

572692

DDX56
Probable ATP-dependent RNA helicase DDX56

1

12

High-throughput

0.479

High

572695

ABCF2
ATP-binding cassette sub-family F member 2

1

2

High-throughput

0.479

High

572697

BAZ1B
Tyrosine-protein kinase BAZ1B

1

9

High-throughput

0.479

High

572700

RAB21
Ras-related protein Rab-21

1

10

High-throughput

0.479

High

572701

DOP2
Protein dopey-2

1

1

High-throughput

0.479

High

572704

HYOU1
Hypoxia up-regulated protein 1

1

15

High-throughput

0.479

High

572708

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

3

High-throughput

0.479

High

313747

SVIL
Supervillin

1

0

High-throughput

0.458

High

572624

LGUL
Lactoylglutathione lyase

1

0

High-throughput

0.458

High

572707

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.458

High

268392

BAF
Barrier-to-autointegration factor

1

3

High-throughput

0.457

High

301262

MTCL2
Microtubule cross-linking factor 2

1

6

Small-scale

0.445

High

427434

ANXA2
Annexin A2

1

1

Small-scale

0.445

High

572658

CIP2A
Protein CIP2A

1

2

Small-scale

0.445

High

50090

HACL2
2-hydroxyacyl-CoA lyase 2

1

1

High-throughput

0.437

High

119918

AP3B1
AP-3 complex subunit beta-1

1

3

High-throughput

0.437

High

130432

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

5

High-throughput

0.437

High

150171

AP3D1
AP-3 complex subunit delta-1

1

8

High-throughput

0.437

High

207884

XPOT
Exportin-T

1

10

High-throughput

0.437

High

224298

RAD21
Double-strand-break repair protein rad21 homolog

1

2

High-throughput

0.437

High

226465

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.437

High

230007

NPA1P
Nucleolar pre-ribosomal-associated protein 1

1

1

High-throughput

0.437

High

240520

DPM1
Dolichol-phosphate mannosyltransferase subunit 1

1

10

High-throughput

0.437

High

260749

H2AY
Core histone macro-H2A.1

1

3

High-throughput

0.437

High

272992

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.437

High

273683

NU155
Nuclear pore complex protein Nup155

1

6

High-throughput

0.437

High

315291

NSA2
Ribosome biogenesis protein NSA2 homolog

1

2

High-throughput

0.437

High

398637

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

4

High-throughput

0.437

High

438684

SRPRA
Signal recognition particle receptor subunit alpha

1

4

High-throughput

0.437

High

506155

PYGB
Glycogen phosphorylase, brain form

1

3

High-throughput

0.437

High

532055

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

3

High-throughput

0.437

High

572584

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

5

High-throughput

0.437

High

572595

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

5

High-throughput

0.437

High

572601

EMD
Emerin

1

5

High-throughput

0.437

High

572604

DHB4
Peroxisomal multifunctional enzyme type 2

1

5

High-throughput

0.437

High

572610

TMM33
Transmembrane protein 33

1

2

High-throughput

0.437

High

572613

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

4

High-throughput

0.437

High

572615

ERF1
Eukaryotic peptide chain release factor subunit 1

1

3

High-throughput

0.437

High

572618

RT34
Small ribosomal subunit protein mS34

1

1

High-throughput

0.437

High

572621

TFAM
Transcription factor A, mitochondrial

1

2

High-throughput

0.437

High

572626

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

1

5

High-throughput

0.437

High

572631

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.437

High

572632

PWP1
Periodic tryptophan protein 1 homolog

1

8

High-throughput

0.437

High

572636

CND2
Condensin complex subunit 2

1

3

High-throughput

0.437

High

572640

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

4

High-throughput

0.437

High

572641

NU188
Nucleoporin NUP188

1

2

High-throughput

0.437

High

572646

TM10C
tRNA methyltransferase 10 homolog C

1

2

High-throughput

0.437

High

572648

TRM1L
TRMT1-like protein

1

2

High-throughput

0.437

High

572649

MON2
Protein MON2 homolog

1

4

High-throughput

0.437

High

572652

PHF6
PHD finger protein 6

1

5

High-throughput

0.437

High

572654

NUP93
Nuclear pore complex protein Nup93

1

5

High-throughput

0.437

High

572655

KRI1
Protein KRI1 homolog

1

6

High-throughput

0.437

High

572656

FBX22
F-box only protein 22

1

1

High-throughput

0.437

High

572660

IPO4
Importin-4

1

7

High-throughput

0.437

High

572665

RT27
Small ribosomal subunit protein mS27

1

2

High-throughput

0.437

High

572666

GCN1
Stalled ribosome sensor GCN1

1

8

High-throughput

0.437

High

572667

NU205
Nuclear pore complex protein Nup205

1

7

High-throughput

0.437

High

572671

ZN512
Zinc finger protein 512

1

2

High-throughput

0.437

High

572673

RBM14
RNA-binding protein 14

1

7

High-throughput

0.437

High

572675

STRBP
Spermatid perinuclear RNA-binding protein

1

3

High-throughput

0.437

High

572676

MMS19
MMS19 nucleotide excision repair protein homolog

1

3

High-throughput

0.437

High

572677

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

6

High-throughput

0.437

High

572684

XPO5
Exportin-5

1

10

High-throughput

0.437

High

572685

SSF1
Suppressor of SWI4 1 homolog

1

1

High-throughput

0.437

High

572686

SAR1A
Small COPII coat GTPase SAR1A

1

10

High-throughput

0.437

High

572687

BAZ1A
Bromodomain adjacent to zinc finger domain protein 1A

1

12

High-throughput

0.437

High

572690

FANCI
Fanconi anemia group I protein

1

6

High-throughput

0.437

High

572691

RBM28
RNA-binding protein 28

1

1

High-throughput

0.437

High

572694

DHCR7
7-dehydrocholesterol reductase

1

2

High-throughput

0.437

High

572696

SEC63
Translocation protein SEC63 homolog

1

12

High-throughput

0.437

High

572699

MRT4
mRNA turnover protein 4 homolog

1

4

High-throughput

0.437

High

572702

NOC2L
Nucleolar complex protein 2 homolog

1

2

High-throughput

0.437

High

572705

TNPO3
Transportin-3

1

13

High-throughput

0.437

High

572706

SRPRB
Signal recognition particle receptor subunit beta

1

19

High-throughput

0.437

High

572650

TMC4
Transmembrane channel-like protein 4

1

0

Small-scale

0.426

High

572661

SCRB1
Scavenger receptor class B member 1

1

0

Small-scale

0.426

High

572672

SPB12
Serpin B12

1

0

Small-scale

0.426

High

572651

ZN467
Zinc finger protein 467

1

0

High-throughput

0.279

Low

572703

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.279

Low

572598

PSB3
Proteasome subunit beta type-3

1

0

High-throughput

0.249

Low

572612

MGN
Protein mago nashi homolog

1

0

High-throughput

0.249

Low

572625

GFPT1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1

1

0

High-throughput

0.249

Low

572644

CC137
Coiled-coil domain-containing protein 137

1

0

High-throughput

0.249

Low

572653

RM41
Large ribosomal subunit protein mL41

1

0

High-throughput

0.249

Low

572693

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

0

High-throughput

0.249

Low

572642

TMCO4
Transmembrane and coiled-coil domain-containing protein 4

1

0

Small-scale

0.232

Low

572682

TM245
Transmembrane protein 245

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024