HitPredict

Interactor 1: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Interactor 2: RING2 (Q99496)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1) (RING-type E3 ubiquitin transferase RING2)
Gene: RNF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.727

Property	Details
Experiments	20850016, 21596310
Identification Methods	unspecified method, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Histone~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 336
+	Hs
		935154 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		RING2_HUMAN (1-336): 4.99e-112: 330: 100.00
+	Hs
		952576 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		RING2_HUMAN (1-336): 4.99e-112: 330: 100.00
+	Hs
		934691 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		RING1_HUMAN (6-336): 8.6e-69: 222: 51.24
+	Hs
		987976 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		RING1_HUMAN (6-336): 8.6e-69: 222: 51.24
+	Hs
		952292 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		RING1_HUMAN (6-336): 8.6e-69: 222: 51.24
+	Hs
		935183 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		PCGF1_HUMAN (28-336): 1.84e-47: 162: 16.88
+	Hs
		952593 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		PCGF1_HUMAN (28-336): 1.84e-47: 162: 16.88
+	Hs
		717680 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		BMI1_HUMAN (34-332): 4.13e-45: 158: 15.51
+	Hs
		717875 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		BMI1_HUMAN (34-332): 4.13e-45: 158: 15.51
+	Hs
		584928 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		RO52_HUMAN (36-286): 4.69e-43: 156: 13.55
+	Hs
		935164 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		BARD1_HUMAN (1-291): 1.2e-38: 147: 12.42
+	Hs
		952582 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		BARD1_HUMAN (1-291): 1.2e-38: 147: 12.42
+	Hs
		935201 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		PCGF6_HUMAN (29-296): 6.61e-39: 142: 14.76
+	Hs
		1086305 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		PCGF6_HUMAN (29-296): 6.61e-39: 142: 14.76
+	Hs
		749363 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		BRCA1_HUMAN (36-214): 1.15e-33: 133: 25.79
+	Hs
		749374 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		BRCA1_HUMAN (36-214): 1.15e-33: 133: 25.79
+	Hs
		477686 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		TRI49_HUMAN (42-303): 1.57e-33: 130: 11.90
+	Hs
		551436 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		RAG1_HUMAN (42-197): 1.72e-29: 121: 20.51
+	Hs
		551443 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		RAG1_HUMAN (42-197): 1.72e-29: 121: 20.51
+	Hs
		935031 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		RN138_HUMAN (34-201): 1.75e-27: 109: 17.06