HitPredict

Interactor 1: H2A2C (Q16777)
Histone H2A type 2-C (H2A-clustered histone 20) (Histone H2A-GL101) (Histone H2A/q)
Gene: H2AC20

Interactor 2: MYSM1 (Q5VVJ2)
Deubiquitinase MYSM1 (2A-DUB) (EC 3.4.19.-) (Myb-like, SWIRM and MPN domain-containing protein 1)
Gene: MYSM1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.649

Property	Details
Experiments	21245042, 17707232
Identification Methods	enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, deubiquitination reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 129 Hs			1 828
+	Hs
		391742 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		MYSM1_HUMAN (1-828): 0: 1085: 100.00
+	Hs
		555498 H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12		MYSM1_HUMAN (1-828): 0: 1085: 100.00
+	Mm
		1149044 H2A2A_MOUSE (1-127): 3.37e-65: 195: 97.64		MYSM1_MOUSE (1-828): 0: 1025: 78.92
+	Hs
		1151361 H2A2A_HUMAN (1-127): 3.37e-65: 195: 97.64		SMRC2_HUMAN (177-520): 4.8e-100: 338: 17.75
+	Hs
		555557 H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12		SMRC2_HUMAN (177-520): 4.8e-100: 338: 17.75
+	Hs
		555574 H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12		SMRC1_HUMAN (186-520): 2.82e-92: 315: 17.97
+	Sc
		392086 H2A1_YEAST (16-129): 1.56e-52: 163: 78.95		SWI3_YEAST (187-542): 9.25e-63: 228: 16.94
+	Sc
		392356 H2A2_YEAST (16-129): 1.63e-52: 163: 78.95		SWI3_YEAST (187-542): 9.25e-63: 228: 16.94
+	Sc
		392479 H2A2_YEAST (16-129): 1.63e-52: 163: 78.95		RSC8_YEAST (286-572): 3.97e-53: 195: 15.18
+	Hs
		555685 H2AX_HUMAN (1-123): 7.38e-64: 192: 95.12		RCOR1_HUMAN (89-212): 3.15e-25: 112: 20.47
+	Hs
		231959 H2A1B_HUMAN (1-127): 8.29e-65: 194: 94.49		KDM1A_HUMAN (226-497): 1.17e-19: 96.5: 14.58