HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: OBSCN (Q5VST9)
Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK)
Gene: OBSCN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 7968
+	Hs
		862088 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		DAPK1_HUMAN (7677-7924): 2.14e-26: 123: 30.42
+	Hs
		1129830 H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62		TITIN_HUMAN (7238-7621): 5.23e-10: 69.5: 12.50
+	Hs
		617962 H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21		TITIN_HUMAN (7238-7621): 5.23e-10: 69.5: 12.50
+	Hs
		1087299 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		TITIN_HUMAN (7238-7621): 5.23e-10: 69.5: 12.50
+	Hs
		1264778 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		TITIN_HUMAN (7238-7621): 5.23e-10: 69.5: 12.50
+	Hs
		883041 H2BFS_HUMAN (1-126): 1.26e-53: 166: 96.83		TITIN_HUMAN (7238-7621): 5.23e-10: 69.5: 12.50
+	Hs
		918561 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		TITIN_HUMAN (7238-7621): 5.23e-10: 69.5: 12.50
+	Hs
		241595 H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41		TITIN_HUMAN (7238-7621): 5.23e-10: 69.5: 12.50
+	Hs
		255826 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		OBSL1_HUMAN (7102-7627): 1.09e-09: 68.4: 10.28
+	Hs
		886166 H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41		TITIN_HUMAN (7238-7621): 5.23e-10: 69.5: 12.50
+	Hs
		256017 H2B1N_HUMAN (1-126): 3.35e-53: 164: 98.41		OBSL1_HUMAN (7102-7627): 1.09e-09: 68.4: 10.28
+	Hs
		1264792 H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62		TITIN_HUMAN (7238-7621): 5.23e-10: 69.5: 12.50