HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	30021884, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 2335
+	Hs
		1129814 H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		1159221 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		883029 H2BFS_HUMAN (1-126): 1.26e-53: 166: 96.83		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		886133 H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Sc
		355849 H2B2_YEAST (3-125): 4.73e-37: 124: 71.55		PRP8_YEAST (23-2335): 0: 3828: 62.28
+	Sc
		355427 H2B1_YEAST (3-125): 1.81e-36: 122: 71.55		PRP8_YEAST (23-2335): 0: 3828: 62.28