Protein: VANG2
Vang-like protein 2 (Loop-tail protein 1 homolog) (Strabismus 1) (Van Gogh-like protein 2)

Gene: VANG2, VANGL2
Organism: Homo sapiens
Interactions: 192
UniProt ID: Q9ULK5

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0001736 - establishment of planar polarity
GO:0001843 - neural tube closure
GO:0001942 - hair follicle development
GO:0001947 - heart looping

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1346664

VANG1
Vang-like protein 1

2

2

Small-scale

0.754

High

1339409

GP156
Probable G-protein coupled receptor 156

3

1

High-throughput

0.662

High

1432382

PININ
Pinin

3

1

High-throughput

0.662

High

159915

DVL2
Segment polarity protein dishevelled homolog DVL-2

3

20

High-throughput

0.650

High

212504

SPIT2
Kunitz-type protease inhibitor 2

3

0

High-throughput

0.638

High

639414

5NTD
5'-nucleotidase

3

0

High-throughput

0.638

High

591392

CD44
CD44 antigen

2

1

High-throughput

0.628

High

622707

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

3

High-throughput

0.628

High

648845

KCNA5
Potassium voltage-gated channel subfamily A member 5

2

4

High-throughput

0.628

High

760512

SDC2
Syndecan-2

2

5

High-throughput

0.628

High

935470

FGF8
Fibroblast growth factor 8

2

1

High-throughput

0.628

High

1371474

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

20

High-throughput

0.628

High

1395090

JPH4
Junctophilin-4

2

1

High-throughput

0.628

High

1409926

KCNS3
Delayed-rectifier potassium channel regulatory subunit KCNS3

2

4

High-throughput

0.628

High

1108273

SQSTM
Sequestosome-1

2

2

Small-scale

0.624

High

684044

PTN3
Tyrosine-protein phosphatase non-receptor type 3

2

10

High-throughput

0.621

High

935279

TERA
Transitional endoplasmic reticulum ATPase

2

1

Small-scale

0.619

High

749822

CADH5
Cadherin-5

2

0

High-throughput

0.602

High

821786

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.602

High

1193275

SV2C
Synaptic vesicle glycoprotein 2C

2

0

High-throughput

0.602

High

1433652

E41L1
Band 4.1-like protein 1

2

10

High-throughput

0.601

High

538104

HSP7C
Heat shock cognate 71 kDa protein

2

0

High-throughput

0.595

High

376089

RASK
GTPase KRas

2

10

High-throughput

0.584

High

978401

RHOB
Rho-related GTP-binding protein RhoB

2

19

High-throughput

0.584

High

1359372

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

2

High-throughput

0.574

High

1436390

MANS1
MANSC domain-containing protein 1

2

1

High-throughput

0.574

High

1358883

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

1

Small-scale

0.565

High

1278831

HDGR2
Hepatoma-derived growth factor-related protein 2

2

1

High-throughput

0.549

High

1348990

ZCH10
Zinc finger CCHC domain-containing protein 10

2

1

High-throughput

0.549

High

595125

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

4

High-throughput

0.536

High

599232

IL7RA
Interleukin-7 receptor subunit alpha

1

1

High-throughput

0.536

High

630379

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

3

High-throughput

0.536

High

718483

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.536

High

726707

SDC4
Syndecan-4

1

5

High-throughput

0.536

High

944428

SYJ2B
Synaptojanin-2-binding protein

1

12

High-throughput

0.536

High

1203829

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.536

High

1325100

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

1

High-throughput

0.536

High

1333622

SIDT2
SID1 transmembrane family member 2

1

1

High-throughput

0.536

High

1459924

I20RA
Interleukin-20 receptor subunit alpha

1

2

High-throughput

0.536

High

1461625

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

3

High-throughput

0.536

High

1461626

E41L3
Band 4.1-like protein 3

1

10

High-throughput

0.536

High

1461630

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

1

High-throughput

0.536

High

951516

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.533

High

1229130

RNF43
E3 ubiquitin-protein ligase RNF43

1

2

High-throughput

0.515

High

596544

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.513

High

1180982

HFE
Hereditary hemochromatosis protein

1

0

High-throughput

0.513

High

1417283

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

1421373

S39A8
Metal cation symporter ZIP8

1

0

High-throughput

0.513

High

1432450

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

1461623

TNF18
Tumor necrosis factor ligand superfamily member 18

1

0

High-throughput

0.513

High

1461628

TMED7
Transmembrane emp24 domain-containing protein 7

1

0

High-throughput

0.513

High

1461629

PCDGL
Protocadherin gamma-C4

1

0

High-throughput

0.513

High

1417327

AP1M1
AP-1 complex subunit mu-1

1

0

Small-scale

0.504

High

1091596

DLG1
Disks large homolog 1

1

6

High-throughput

0.501

High

134906

SAP18
Histone deacetylase complex subunit SAP18

1

1

High-throughput

0.489

High

1057036

FMR1
Fragile X messenger ribonucleoprotein 1

1

1

High-throughput

0.489

High

1324495

AN36B
Ankyrin repeat domain-containing protein 36B

1

1

High-throughput

0.489

High

1346572

RP9
Retinitis pigmentosa 9 protein

1

1

High-throughput

0.489

High

1429110

NXF2
Nuclear RNA export factor 2

1

1

High-throughput

0.489

High

1451168

ARGL1
Arginine and glutamate-rich protein 1

1

1

High-throughput

0.489

High

1458277

IKBL1
NF-kappa-B inhibitor-like protein 1

1

1

High-throughput

0.489

High

1461622

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.489

High

48841

ESYT2
Extended synaptotagmin-2

1

3

High-throughput

0.479

High

126871

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

189921

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

221197

SPY2
Protein sprouty homolog 2

1

1

High-throughput

0.479

High

226258

STX6
Syntaxin-6

1

2

High-throughput

0.479

High

299427

FLOT1
Flotillin-1

1

1

High-throughput

0.479

High

341168

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.479

High

374278

RASN
GTPase NRas

1

10

High-throughput

0.479

High

412797

NTRK1
High affinity nerve growth factor receptor

1

13

High-throughput

0.479

High

463838

LYN
Tyrosine-protein kinase Lyn

1

2

High-throughput

0.479

High

464076

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

10

High-throughput

0.479

High

466524

RHOC
Rho-related GTP-binding protein RhoC

1

15

High-throughput

0.479

High

540750

LAMP1
Lysosome-associated membrane glycoprotein 1

1

5

High-throughput

0.479

High

562484

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

High-throughput

0.479

High

581372

RAC2
Ras-related C3 botulinum toxin substrate 2

1

15

High-throughput

0.479

High

583019

EZRI
Ezrin

1

10

High-throughput

0.479

High

601496

RHOQ
Rho-related GTP-binding protein RhoQ

1

19

High-throughput

0.479

High

604268

CXA1
Gap junction alpha-1 protein

1

3

High-throughput

0.479

High

605846

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

High-throughput

0.479

High

611414

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

3

High-throughput

0.479

High

631018

RAB4A
Ras-related protein Rab-4A

1

5

High-throughput

0.479

High

631554

RAB5A
Ras-related protein Rab-5A

1

5

High-throughput

0.479

High

643134

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

4

High-throughput

0.479

High

648731

FGFR4
Fibroblast growth factor receptor 4

1

14

High-throughput

0.479

High

674374

BRD2
Bromodomain-containing protein 2

1

3

High-throughput

0.479

High

693129

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.479

High

710564

EPHA2
Ephrin type-A receptor 2

1

6

High-throughput

0.479

High

715842

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

770325

RL22
Large ribosomal subunit protein eL22

1

1

High-throughput

0.479

High

845857

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.479

High

880740

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.479

High

901101

RAB5C
Ras-related protein Rab-5C

1

5

High-throughput

0.479

High

902139

RAB9A
Ras-related protein Rab-9A

1

6

High-throughput

0.479

High

910250

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

936483

AFAD
Afadin

1

7

High-throughput

0.479

High

953757

RAC3
Ras-related C3 botulinum toxin substrate 3

1

17

High-throughput

0.479

High

955748

CDC42
Cell division control protein 42 homolog

1

19

High-throughput

0.479

High

962628

RHOA
Transforming protein RhoA

1

17

High-throughput

0.479

High

962858

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

975315

ARF6
ADP-ribosylation factor 6

1

2

High-throughput

0.479

High

976657

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.479

High

988819

RAC1
Ras-related C3 botulinum toxin substrate 1

1

17

High-throughput

0.479

High

1004236

CXAR
Coxsackievirus and adenovirus receptor

1

1

High-throughput

0.479

High

1015903

RHOG
Rho-related GTP-binding protein RhoG

1

15

High-throughput

0.479

High

1041367

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

1087337

STX4
Syntaxin-4

1

3

High-throughput

0.479

High

1145168

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.479

High

1151928

RHOH
Rho-related GTP-binding protein RhoH

1

19

High-throughput

0.479

High

1159902

OCLN
Occludin

1

1

High-throughput

0.479

High

1233569

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1245150

RHDF2
Inactive rhomboid protein 2

1

3

High-throughput

0.479

High

1271050

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1293204

TMM17
Transmembrane protein 17

1

1

High-throughput

0.479

High

1323041

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.479

High

1353305

PARD3
Partitioning defective 3 homolog

1

7

High-throughput

0.479

High

1366911

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

1395990

DNJC1
DnaJ homolog subfamily C member 1

1

4

High-throughput

0.479

High

1396655

RHOV
Rho-related GTP-binding protein RhoV

1

19

High-throughput

0.479

High

1401255

PANX1
Pannexin-1

1

1

High-throughput

0.479

High

1401729

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

1

High-throughput

0.479

High

1403825

RMD3
Regulator of microtubule dynamics protein 3

1

1

High-throughput

0.479

High

1412717

ESYT1
Extended synaptotagmin-1

1

3

High-throughput

0.479

High

1433000

DNJC5
DnaJ homolog subfamily C member 5

1

3

High-throughput

0.479

High

1433577

RHOJ
Rho-related GTP-binding protein RhoJ

1

19

High-throughput

0.479

High

1438241

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1453926

TM216
Transmembrane protein 216

1

1

High-throughput

0.479

High

1461624

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.479

High

845494

PE2R3
Prostaglandin E2 receptor EP3 subtype

1

0

High-throughput

0.458

High

1286954

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.458

High

1117336

ARFRP
ADP-ribosylation factor-related protein 1

1

5

Small-scale

0.457

High

616822

SDC1
Syndecan-1

1

5

High-throughput

0.445

High

877728

SL9A3
Sodium/hydrogen exchanger 3

1

3

High-throughput

0.445

High

1133817

SL9A5
Sodium/hydrogen exchanger 5

1

3

High-throughput

0.445

High

1288944

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

1

High-throughput

0.445

High

1310978

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

1

High-throughput

0.445

High

1353738

MOT10
Monocarboxylate transporter 10

1

1

High-throughput

0.445

High

140028

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

174146

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.437

High

327498

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

417841

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.437

High

418510

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.437

High

837899

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

High-throughput

0.437

High

847746

SSRA
Translocon-associated protein subunit alpha

1

1

High-throughput

0.437

High

895151

EMD
Emerin

1

1

High-throughput

0.437

High

956541

RAB2A
Ras-related protein Rab-2A

1

5

High-throughput

0.437

High

1128865

NBR1
Next to BRCA1 gene 1 protein

1

1

Small-scale

0.437

High

1141357

BRD3
Bromodomain-containing protein 3

1

3

High-throughput

0.437

High

1146493

KS6A2
Ribosomal protein S6 kinase alpha-2

1

3

High-throughput

0.437

High

1258324

MOB2
MOB kinase activator 2

1

2

High-throughput

0.437

High

1334060

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.437

High

1337719

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.437

High

1352400

RHBL4
Rhomboid-related protein 4

1

3

High-throughput

0.437

High

1382003

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1383166

LRC59
Leucine-rich repeat-containing protein 59

1

3

High-throughput

0.437

High

1404279

SEC62
Translocation protein SEC62

1

1

High-throughput

0.437

High

1414503

DERL1
Derlin-1

1

1

High-throughput

0.437

High

1431288

DJC25
DnaJ homolog subfamily C member 25

1

4

High-throughput

0.437

High

1431789

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

1

High-throughput

0.437

High

1434420

RNF41
E3 ubiquitin-protein ligase NRDP1

1

2

Small-scale

0.437

High

1436362

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.437

High

1439418

E41LA
Band 4.1-like protein 4A

1

10

High-throughput

0.437

High

1446686

LUC7L
Putative RNA-binding protein Luc7-like 1

1

3

High-throughput

0.437

High

1448178

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.437

High

1450135

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

1452724

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.437

High

1454859

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.437

High

1459074

DNJ5B
DnaJ homolog subfamily C member 5B

1

3

High-throughput

0.437

High

1459627

SEC63
Translocation protein SEC63 homolog

1

2

High-throughput

0.437

High

1459828

TBK1
Serine/threonine-protein kinase TBK1

1

1

Small-scale

0.437

High

255283

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.426

High

530563

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

1119360

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

1236376

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1010123

DLK1
Protein delta homolog 1

1

1

High-throughput

0.407

High

1145434

RNPS1
RNA-binding protein with serine-rich domain 1

1

1

High-throughput

0.407

High

1334373

IN80E
INO80 complex subunit E

1

1

High-throughput

0.407

High

1461627

LC7L2
Putative RNA-binding protein Luc7-like 2

1

3

High-throughput

0.407

High

1446723

TMM9B
Transmembrane protein 9B

2

0

High-throughput

0.328

High

239405

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

1

0

Small-scale

0.249

Low

853753

MK08
Mitogen-activated protein kinase 8

1

0

Small-scale

0.249

Low

905283

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.249

Low

967008

1433G
14-3-3 protein gamma

1

0

High-throughput

0.249

Low

1095846

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

Small-scale

0.249

Low

1256066

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1278145

MAVS
Mitochondrial antiviral-signaling protein

1

0

Small-scale

0.249

Low

1386625

OPTN
Optineurin

1

0

Small-scale

0.249

Low

1416104

TRAIP
E3 ubiquitin-protein ligase TRAIP

1

0

Small-scale

0.249

Low

1429882

TOLIP
Toll-interacting protein

1

0

Small-scale

0.249

Low

1438432

POPD2
Popeye domain-containing protein 2

1

0

High-throughput

0.249

Low

1461631

TX264
Testis-expressed protein 264

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025