HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: UBP49 (Q70CQ1)
Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.4.19.12) (Deubiquitinating enzyme 49) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49)
Gene: USP49

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	23824326
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 688
+	Hs
		707745 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBP44_HUMAN (1-682): 0: 543: 58.36
+	Hs
		1282957 H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04		UBP44_HUMAN (1-682): 0: 543: 58.36
+	Hs
		271037 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBP2_HUMAN (55-659): 4e-109: 344: 19.50
+	Hs
		777048 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		UBP8_HUMAN (109-660): 5.19e-103: 341: 19.27
+	Hs
		1087499 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		UBP20_HUMAN (2-678): 2.8e-97: 321: 17.75
+	Hs
		1087411 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		UBP42_HUMAN (204-686): 5.52e-92: 313: 19.63
+	Hs
		1087489 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		UBP22_HUMAN (283-662): 9.54e-98: 312: 24.01
+	Hs
		707794 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBP22_HUMAN (283-662): 9.54e-98: 312: 24.01
+	Hs
		707665 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBP51_HUMAN (276-662): 5.38e-94: 308: 24.15
+	Hs
		420891 H2B1J_HUMAN (1-126): 7.8e-54: 166: 99.21		UBP36_HUMAN (153-685): 9.16e-88: 299: 20.37
+	Hs
		241654 H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41		UBP36_HUMAN (153-685): 9.16e-88: 299: 20.37
+	Hs
		707772 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBP36_HUMAN (153-685): 9.16e-88: 299: 20.37
+	Hs
		707785 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBP21_HUMAN (312-655): 2e-91: 297: 22.69
+	Hs
		905383 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		UBP46_HUMAN (296-658): 2.05e-93: 295: 23.12
+	Hs
		905394 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		UBP46_HUMAN (296-658): 2.05e-93: 295: 23.12
+	Hs
		259286 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		UBP12_HUMAN (279-658): 1.04e-92: 294: 22.39
+	Sc
		355943 H2B2_YEAST (3-125): 4.73e-37: 124: 71.55		UBP8_YEAST (249-660): 5.53e-89: 287: 27.58
+	Sc
		355547 H2B1_YEAST (3-125): 1.81e-36: 122: 71.55		UBP8_YEAST (249-660): 5.53e-89: 287: 27.58
+	Hs
		918801 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		UBP3_HUMAN (4-160): 5.8e-25: 111: 23.08
+	Hs
		707807 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBP3_HUMAN (4-160): 5.8e-25: 111: 23.08