HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: KAT6B (Q8WYB5)
Histone acetyltransferase KAT6B (EC 2.3.1.48) (Histone acetyltransferase MOZ2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (MYST-4) (Monocytic leukemia zinc finger protein-related factor)
Gene: KAT6B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 2073
+	Hs
		617961 H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21		KAT6B_HUMAN (1-2073): 0: 1251: 100.00
+	Hs
		1264460 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		KAT6B_HUMAN (1-2073): 0: 1251: 100.00
+	Hs
		309661 H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21		KAT7_HUMAN (378-991): 1.23e-169: 534: 34.38
+	Hs
		309686 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		KAT7_HUMAN (378-991): 1.23e-169: 534: 34.38
+	Hs
		309707 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		KAT7_HUMAN (378-991): 1.23e-169: 534: 34.38
+	Hs
		1087406 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		KAT8_HUMAN (545-1000): 9.27e-159: 498: 36.03
+	Hs
		918694 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		KAT8_HUMAN (545-1000): 9.27e-159: 498: 36.03
+	Mm
		1145470 H2B2B_MOUSE (1-126): 2.34e-54: 168: 97.62		KAT5_MOUSE (499-991): 2.38e-138: 444: 31.86
+	Hs
		918578 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		KAT5_HUMAN (499-991): 8.28e-139: 445: 31.86
+	Hs
		1129832 H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62		KAT6A_HUMAN (1-493): 4.83e-85: 313: 60.69
+	Hs
		617965 H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21		KAT6A_HUMAN (1-493): 4.83e-85: 313: 60.69
+	Hs
		1087309 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		KAT6A_HUMAN (1-493): 4.83e-85: 313: 60.69
+	Hs
		1274476 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		MYH2_HUMAN (905-1786): 7.53e-75: 279: 11.05
+	Hs
		1087307 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		REQU_HUMAN (174-317): 1.21e-46: 175: 43.54
+	Hs
		918573 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		REQU_HUMAN (174-317): 1.21e-46: 175: 43.54
+	Hs
		1129828 H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62		PHF10_HUMAN (171-336): 4.29e-43: 167: 34.32
+	Hs
		918717 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BAZ1A_HUMAN (272-534): 6.46e-41: 168: 22.47
+	Hs
		1087288 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		PHF10_HUMAN (171-336): 4.29e-43: 167: 34.32
+	Hs
		918547 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		PHF10_HUMAN (171-336): 4.29e-43: 167: 34.32
+	Hs
		918533 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		KMT2C_HUMAN (229-333): 8.99e-24: 112: 33.33