HitPredict

Interactor 1: H0Y2S9 (H0Y2S9)
Myosin phosphatase Rho interacting protein
Gene: MPRIP

Interactor 2: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1794 Hs			1 327
+	Hs
		906507 MPRIP_HUMAN (2-465): 2e-71: 263: 53.72		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		906595 TARA_HUMAN (1383-1732): 3.73e-69: 261: 40.56		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		906127 TARA_HUMAN (1383-1732): 3.73e-69: 261: 40.56		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Mm
		906349 TARA_MOUSE (17-474): 8.69e-69: 259: 22.98		PP1A_MOUSE (1-326): 0: 576: 88.49
+	Hs
		737880 MPRIP_HUMAN (2-465): 2e-71: 263: 53.72		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		738038 TARA_HUMAN (1383-1732): 3.73e-69: 261: 40.56		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		905840 CENPE_HUMAN (342-1792): 5.97e-43: 175: 10.73		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Hs
		724747 MYH9_HUMAN (2-675): 4.91e-29: 129: 9.88		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		724746 MYH9_HUMAN (2-675): 4.91e-29: 129: 9.88		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Hs
		724689 MYH9_HUMAN (2-675): 4.91e-29: 129: 9.88		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Mm
		906240 MYH6_MOUSE (722-1776): 1.2e-26: 121: 11.89		PP1A_MOUSE (1-326): 0: 576: 88.49
+	Hs
		528366 MYH6_HUMAN (560-1719): 3.12e-25: 117: 11.38		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Hs
		906645 MYO5A_HUMAN (56-480): 5.37e-16: 86.6: 12.36		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Xl
		193799 O42263_XENLA (690-1794): 9.79e-18: 92.7: 8.93		PP1GA_XENLA (1-327): 0: 570: 86.89
+	Hs
		931058 MRCKB_HUMAN (30-683): 4.92e-40: 165: 14.18		PP2AA_HUMAN (8-303): 2.77e-176: 491: 45.79
+	Hs
		737809 NUMA1_HUMAN (1224-1791): 1.57e-14: 81.9: 12.57		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Dm
		819254 Q0KI67_DROME (33-582): 2.5e-13: 77.9: 19.55		PP1B_DROME (1-322): 0: 568: 90.37
+	Hs
		725131 MYH10_HUMAN (825-1794): 6.44e-33: 142: 9.82		PP2AB_HUMAN (8-303): 1.26e-176: 492: 46.13
+	Dm
		1213450 Q8INC3_DROME (33-582): 1.59e-13: 78.7: 19.55		Q8T0U6_DROME (18-322): 0: 550: 91.48
+	Hs
		724764 MYH9_HUMAN (2-675): 4.91e-29: 129: 9.88		PP2AA_HUMAN (8-303): 2.77e-176: 491: 45.79