Protein: HD
Huntingtin (Huntington disease protein homolog) (HD protein homolog) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]

Gene: HD, Htt
Organism: Mus musculus
Interactions: 20
UniProt ID: P42859

Gene Ontology (top 5):
GO:0000050 - urea cycle
GO:0000052 - citrulline metabolic process
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005776 - autophagosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

266955

ULK1
Serine/threonine-protein kinase ULK1

1

8

Small-scale

0.500

High

312371

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

1

Small-scale

0.500

High

844158

SQSTM
Sequestosome-1

1

3

Small-scale

0.500

High

205252

AXIN1
Axin-1

1

3

Small-scale

0.479

High

549490

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

1

2

Small-scale

0.479

High

844155

CASP3
Caspase-3

1

4

Small-scale

0.479

High

844156

CTNB1
Catenin beta-1

1

3

Small-scale

0.479

High

844157

FBW1A
F-box/WD repeat-containing protein 1A

1

1

Small-scale

0.479

High

844159

HDAC4
Histone deacetylase 4

1

2

Small-scale

0.479

High

844161

PAK2
Serine/threonine-protein kinase PAK 2

1

4

Small-scale

0.479

High

844162

REST
RE1-silencing transcription factor

1

4

Small-scale

0.479

High

204918

STX1A
Syntaxin-1A

1

7

High-throughput

0.445

High

598655

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

3

High-throughput

0.445

High

844153

SNP25
Synaptosomal-associated protein 25

1

3

High-throughput

0.445

High

844154

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

3

High-throughput

0.445

High

844163

CUL2
Cullin-2

1

4

High-throughput

0.445

High

147396

CA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1

1

2

High-throughput

0.407

High

844151

PRS7
26S proteasome regulatory subunit 7

1

4

High-throughput

0.407

High

844152

KPYM
Pyruvate kinase PKM

1

3

High-throughput

0.407

High

844160

SPAT7
Spermatogenesis-associated protein 7 homolog

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025