Interactor 1: MEP1B (Q16820)
Meprin A subunit beta (EC 3.4.24.63) (Endopeptidase-2) (Meprin B) (N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta)
Gene: MEP1B

Interactor 2: MEP1B (Q16820)
Meprin A subunit beta (EC 3.4.24.63) (Endopeptidase-2) (Meprin B) (N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta)
Gene: MEP1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 22988105, 27180358
Identification Methods x-ray crystallography, split luciferase complementation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Astacin~Astacin, Astacin~MAM, MAM~MAM
Common GO terms GO:0004222 - metalloendopeptidase activity
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0006508 - proteolysis
GO:0006954 - inflammatory response
and 2 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 701
Hs

1 701
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+ Rn
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024