HitPredict

Interactor 1: PTPRO (Q16827)
Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2)
Gene: PTPRO

Interactor 2: TMX1 (Q9H3N1)
Thioredoxin-related transmembrane protein 1 (Protein disulfide-isomerase TMX1) (EC 5.3.4.1) (Thioredoxin domain-containing protein 1) (Transmembrane Trx-related protein)
Gene: TMX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	27432908, 28675297
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1216 Hs			1 280
+	Hs
		1087982 PTPRO_HUMAN (1-1216): 0: 2236: 100.00		TMX4_HUMAN (20-261): 3.55e-53: 178: 41.98
+	Hs
		1087979 PTPRO_HUMAN (1-1216): 0: 2236: 100.00		ERP44_HUMAN (1-161): 1.35e-38: 141: 23.12
+	Hs
		1067718 PTPRO_HUMAN (1-1216): 0: 2236: 100.00		PDIA6_HUMAN (25-146): 1.28e-34: 131: 31.01
+	Hs
		531846 PTPRO_HUMAN (1-1216): 0: 2236: 100.00		PDIA4_HUMAN (119-266): 7.26e-15: 76.3: 9.68
+	Hs
		1087956 PTPRO_HUMAN (1-1216): 0: 2236: 100.00		DJC10_HUMAN (64-264): 2.26e-14: 74.8: 10.95
+	Hs
		671825 PTPRO_HUMAN (1-1216): 0: 2236: 100.00		PDIA3_HUMAN (147-256): 2.92e-14: 74.4: 12.61
+	Hs
		423243 PTPRO_HUMAN (1-1216): 0: 2236: 100.00		PDIA1_HUMAN (66-256): 1.82e-10: 62.8: 10.68
+	Hs
		1295307 PTN18_HUMAN (919-1216): 2.35e-120: 382: 30.52		TMX3_HUMAN (6-270): 4.15e-49: 170: 15.94
+	Hs
		577022 PTPRA_HUMAN (922-1196): 1.24e-99: 337: 35.48		PDIA6_HUMAN (25-146): 1.28e-34: 131: 31.01
+	Hs
		577042 PTPRA_HUMAN (922-1196): 1.24e-99: 337: 35.48		TXND5_HUMAN (24-135): 1.06e-32: 126: 25.00
+	Hs
		660849 PTPRM_HUMAN (918-1199): 6.38e-60: 228: 27.95		PDIA6_HUMAN (25-146): 1.28e-34: 131: 31.01
+	Hs
		1067777 PTPRU_HUMAN (918-1200): 4.38e-58: 222: 29.63		PDIA6_HUMAN (25-146): 1.28e-34: 131: 31.01
+	Hs
		660862 PTPRM_HUMAN (918-1199): 6.38e-60: 228: 27.95		DJC10_HUMAN (64-264): 2.26e-14: 74.8: 10.95
+	Hs
		531930 PTPRU_HUMAN (918-1200): 4.38e-58: 222: 29.63		PDIA4_HUMAN (119-266): 7.26e-15: 76.3: 9.68
+	Hs
		1220443 PTPRU_HUMAN (918-1200): 4.38e-58: 222: 29.63		DJC10_HUMAN (64-264): 2.26e-14: 74.8: 10.95
+	Hs
		671887 PTPRU_HUMAN (918-1200): 4.38e-58: 222: 29.63		PDIA3_HUMAN (147-256): 2.92e-14: 74.4: 12.61
+	Hs
		423314 PTPRU_HUMAN (918-1200): 4.38e-58: 222: 29.63		PDIA1_HUMAN (66-256): 1.82e-10: 62.8: 10.68