HitPredict

Interactor 1: DUS6 (Q16828)
Dual specificity protein phosphatase 6 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PYST1) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3)
Gene: DUSP6

Interactor 2: DUS6 (Q16828)
Dual specificity protein phosphatase 6 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PYST1) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3)
Gene: DUSP6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 27432908, 31980649
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DSPc~DSPc, Rhodanese~Rhodanese
Common GO terms GO:0000165 - MAPK cascade
GO:0001933 - negative regulation of protein phosphorylation
GO:0004725 - protein tyrosine phosphatase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 17 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 381
Hs

1 381
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Last updated: 15 Jul 2024