Protein: TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1 (Terminal deoxynucleotidyltransferase-interacting factor 1) (TdIF1) (TdT-interacting factor 1)

Gene: TDIF1, DNTTIP1
Organism: Homo sapiens
Interactions: 100
UniProt ID: Q9H147

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1245179

MDEAS
Mitotic deacetylase-associated SANT domain protein

3

2

High-throughput

0.871

High

1399884

TREF1
Transcriptional-regulating factor 1

3

2

High-throughput

0.871

High

1110063

HDAC1
Histone deacetylase 1

7

2

High-throughput

0.751

High

1368109

HDAC2
Histone deacetylase 2

3

2

High-throughput

0.675

High

629162

CCNA2
Cyclin-A2

4

0

High-throughput

0.670

High

1311783

HOMEZ
Homeobox and leucine zipper protein Homez

2

3

High-throughput

0.633

High

1238117

HMBX1
Homeobox-containing protein 1

2

5

High-throughput

0.606

High

143244

NFIB
Nuclear factor 1 B-type

2

3

High-throughput

0.584

High

998792

H31
Histone H3.1

2

1

High-throughput

0.584

High

848438

MAGA6
Melanoma-associated antigen 6

2

0

High-throughput

0.580

High

935626

MFAP1
Microfibrillar-associated protein 1

2

0

High-throughput

0.580

High

1366747

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

2

0

High-throughput

0.580

High

1394885

EAF1
ELL-associated factor 1

2

0

High-throughput

0.580

High

396918

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

1367239

ESR2
Estrogen receptor beta

2

3

High-throughput

0.571

High

402309

TDT
DNA nucleotidylexotransferase

1

0

Small-scale

0.549

High

401466

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

0

High-throughput

0.547

High

1380422

ABTB1
Ankyrin repeat and BTB/POZ domain-containing protein 1

1

0

Small-scale

0.537

High

1163198

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.536

High

1430797

FOXJ2
Forkhead box protein J2

1

1

High-throughput

0.536

High

187180

PPM1G
Protein phosphatase 1G

1

0

High-throughput

0.513

High

443100

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

0

High-throughput

0.513

High

487740

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.513

High

959052

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

1091079

FOXF2
Forkhead box protein F2

1

0

High-throughput

0.513

High

1093043

CDC16
Cell division cycle protein 16 homolog

1

0

High-throughput

0.513

High

1430796

PLK2
Serine/threonine-protein kinase PLK2

1

0

High-throughput

0.513

High

1430799

LAS1L
Ribosomal biogenesis protein LAS1L

1

0

High-throughput

0.513

High

843970

HD
Huntingtin

1

0

High-throughput

0.493

High

1279740

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

1430798

UBQL1
Ubiquilin-1

1

0

High-throughput

0.493

High

246935

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.486

High

1380847

TRI63
E3 ubiquitin-protein ligase TRIM63

1

1

High-throughput

0.481

High

1419286

TRI55
Tripartite motif-containing protein 55

1

1

High-throughput

0.481

High

210112

CRX
Cone-rod homeobox protein

1

4

High-throughput

0.479

High

225107

TLX3
T-cell leukemia homeobox protein 3

1

6

High-throughput

0.479

High

226598

TLX2
T-cell leukemia homeobox protein 2

1

3

High-throughput

0.479

High

239996

SOX15
Transcription factor SOX-15

1

3

High-throughput

0.479

High

373117

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

406631

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

474277

NFIC
Nuclear factor 1 C-type

1

3

High-throughput

0.479

High

520363

ANDR
Androgen receptor

1

3

High-throughput

0.479

High

540945

ERG
Transcriptional regulator ERG

1

1

High-throughput

0.479

High

607097

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

662275

PAX7
Paired box protein Pax-7

1

4

High-throughput

0.479

High

685344

PAX6
Paired box protein Pax-6

1

4

High-throughput

0.479

High

725316

TLX1
T-cell leukemia homeobox protein 1

1

4

High-throughput

0.479

High

775908

HNF1B
Hepatocyte nuclear factor 1-beta

1

5

High-throughput

0.479

High

834050

HNF4A
Hepatocyte nuclear factor 4-alpha

1

2

High-throughput

0.479

High

872734

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.479

High

887210

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.479

High

895796

LHX2
LIM/homeobox protein Lhx2

1

1

High-throughput

0.479

High

938501

PAX9
Paired box protein Pax-9

1

4

High-throughput

0.479

High

942463

GSC
Homeobox protein goosecoid

1

2

High-throughput

0.479

High

981084

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

1017199

H33
Histone H3.3

1

1

High-throughput

0.479

High

1040077

PAX2
Paired box protein Pax-2

1

4

High-throughput

0.479

High

1056647

PAX8
Paired box protein Pax-8

1

4

High-throughput

0.479

High

1088004

NFIA
Nuclear factor 1 A-type

1

3

High-throughput

0.479

High

1133651

NFIX
Nuclear factor 1 X-type

1

3

High-throughput

0.479

High

1379948

LHX4
LIM/homeobox protein Lhx4

1

1

High-throughput

0.479

High

1405430

FEV
Protein FEV

1

1

High-throughput

0.479

High

1430792

SOX17
Transcription factor SOX-17

1

3

High-throughput

0.479

High

1430793

NANOG
Homeobox protein NANOG

1

6

High-throughput

0.479

High

282781

E2F6
Transcription factor E2F6

1

0

Small-scale

0.460

High

132291

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

173345

XPO1
Exportin-1

1

0

High-throughput

0.458

High

194342

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

419197

H2A1B
Histone H2A type 1-B/E

1

0

High-throughput

0.458

High

538467

EGR2
E3 SUMO-protein ligase EGR2

1

0

High-throughput

0.458

High

589654

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

662497

GATA2
Endothelial transcription factor GATA-2

1

0

High-throughput

0.458

High

696469

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

769141

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

944735

KLF3
Krueppel-like factor 3

1

0

High-throughput

0.458

High

980305

H4
Histone H4

1

0

High-throughput

0.458

High

1032045

TFAP4
Transcription factor AP-4

1

0

Small-scale

0.458

High

1033220

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

1037818

IRF8
Interferon regulatory factor 8

1

0

High-throughput

0.458

High

1129738

MDC1
Mediator of DNA damage checkpoint protein 1

1

0

High-throughput

0.458

High

1160890

TBR1
T-box brain protein 1

1

0

High-throughput

0.458

High

1351155

SP7
Transcription factor Sp7

1

0

High-throughput

0.458

High

1352426

SH3R2
E3 ubiquitin-protein ligase SH3RF2

1

0

Small-scale

0.458

High

1430794

GCM1
Chorion-specific transcription factor GCMa

1

0

High-throughput

0.458

High

584143

FOSL2
Fos-related antigen 2

1

0

High-throughput

0.426

High

1399443

WDFY2
WD repeat and FYVE domain-containing protein 2

3

0

High-throughput

0.347

High

1349627

PHOP2
Pyridoxal phosphate phosphatase PHOSPHO2

2

0

High-throughput

0.328

High

1430795

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

451446

NFM
Neurofilament medium polypeptide

1

0

High-throughput

0.279

Low

581586

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

0

High-throughput

0.279

Low

907693

CLCN2
Chloride channel protein 2

1

0

High-throughput

0.279

Low

109508

G5E9A7
DM1 locus, WD repeat containing

1

0

High-throughput

0.268

Low

160761

TOR1A
Torsin-1A

1

0

High-throughput

0.268

Low

369749

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.268

Low

650405

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

896883

DYN2
Dynamin-2

1

0

High-throughput

0.268

Low

1292933

Q86WV8
TSC complex subunit 1

1

0

High-throughput

0.268

Low

591365

CD44
CD44 antigen

1

0

High-throughput

0.232

Low

616808

SDC1
Syndecan-1

1

0

High-throughput

0.232

Low

1335715

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025