Interactor 1: NDC80 (Q17635)
Kinetochore protein ndc-80 (CeNDC-80) (Hec1 homolog)
Gene: ndc-80

Interactor 2: NUF2 (Q21952)
Kinetochore protein Nuf2 homolog (CeNuf2) (Kinetochore protein him-10) (Protein high incidence of males 10)
Gene: him-10

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.920

The method score is based on:

Property Details
Experiments 17129783, 24231804, 14704431, 18692475, unassigned701
Identification Methods affinity chromatography technology, two hybrid, molecular sieving, two hybrid pooling approach
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ndc80_HEC~Nuf2
Common GO terms GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005874 - microtubule
GO:0008017 - microtubule binding
GO:0008608 - attachment of spindle microtubules to kinetochore
and 4 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 590
Ce

1 490
+ Hs
+ Rn
+ Gg
+ Xl
+ Hs
+ Hs
+ Rn
+ Rn
+ Hs
+ Sc
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024