HitPredict

Interactor 1: Q17795 (Q17795)
CRIB domain-containing protein
Gene: wsp-1

Interactor 2: Q95PW9 (Q95PW9)
NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family
Gene: nck-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	22383893, 23549480
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 607 Ce			1 395
+	Ce
		106662 Q17795_CAEEL (1-607): 1.26e-154: 459: 100.00		SRC1_CAEEL (214-378): 5.96e-19: 90.5: 32.20
+	Hs
		126885 WASL_HUMAN (12-320): 2.36e-77: 256: 26.77		NCK2_HUMAN (2-393): 1.95e-85: 266: 37.31
+	Hs
		126909 WASL_HUMAN (12-320): 2.36e-77: 256: 26.77		NCK1_HUMAN (2-394): 6.74e-80: 252: 37.78
+	Hs
		209002 WASP_HUMAN (27-403): 3.06e-64: 221: 21.39		NCK2_HUMAN (2-393): 1.95e-85: 266: 37.31
+	Mm
		936473 WASP_MOUSE (27-458): 7.51e-68: 231: 22.25		NCK1_MOUSE (2-394): 4.78e-80: 252: 37.28
+	Hs
		126898 WASL_HUMAN (12-320): 2.36e-77: 256: 26.77		LCK_HUMAN (176-378): 5.2e-55: 190: 30.05
+	Mm
		411923 WASP_MOUSE (27-458): 7.51e-68: 231: 22.25		LCK_MOUSE (176-378): 5.27e-54: 188: 30.05
+	Hs
		126965 WASL_HUMAN (12-320): 2.36e-77: 256: 26.77		ITSN2_HUMAN (8-285): 3.74e-34: 136: 19.61
+	Hs
		126936 WASL_HUMAN (12-320): 2.36e-77: 256: 26.77		ITSN1_HUMAN (5-269): 1.04e-31: 129: 14.46
+	Hs
		126930 WASL_HUMAN (12-320): 2.36e-77: 256: 26.77		GRB2_HUMAN (5-175): 1.72e-28: 112: 20.37
+	Hs
		3131 WASL_HUMAN (12-320): 2.36e-77: 256: 26.77		A0A0S2Z4D7_HUMAN (1-142): 3.47e-23: 97.1: 44.30
+	Rn
		94091 F1LSG0_RAT (13-320): 3.49e-81: 266: 27.83		ITSN1_RAT (57-227): 7.79e-11: 66.1: 20.90
+	Hs
		126905 WASL_HUMAN (12-320): 2.36e-77: 256: 26.77		SRC_HUMAN (43-217): 1.14e-12: 71.3: 16.95
+	Mm
		643073 WASP_MOUSE (27-458): 7.51e-68: 231: 22.25		P85A_MOUSE (270-393): 5.53e-20: 94.1: 19.69
+	Dm
		112580 Q9VAT0_DROME (13-605): 5.49e-74: 248: 25.12		M9ND00_DROME (4-76): 6.13e-14: 75.9: 24.66
+	Dm
		1361426 Q9VAT0_DROME (13-605): 5.49e-74: 248: 25.12		Q9VIF7_DROME (4-66): 1.56e-13: 74.3: 28.57
+	Mm
		763384 WASP_MOUSE (27-458): 7.51e-68: 231: 22.25		FYN_MOUSE (6-244): 6.88e-19: 90.2: 12.45
+	Mm
		435880 WASP_MOUSE (27-458): 7.51e-68: 231: 22.25		HCK_MOUSE (2-188): 1.34e-18: 89.4: 14.89
+	Mm
		403427 WASP_MOUSE (27-458): 7.51e-68: 231: 22.25		SRC_MOUSE (43-180): 9.38e-12: 68.3: 21.58
+	Mm
		729748 WASP_MOUSE (27-458): 7.51e-68: 231: 22.25		BTK_MOUSE (2-129): 7.13e-11: 66: 17.05