Protein: NOP58
Nucleolar protein 58 (Nucleolar protein 5)

Gene: NOP58
Organism: Homo sapiens
Interactions: 229
UniProt ID: Q9Y2X3

Gene Ontology (top 5):
GO:0001094 - TFIID-class transcription factor complex binding
GO:0001650 - fibrillar center
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

603801

FBRL
rRNA 2'-O-methyltransferase fibrillarin

10

8

Small-scale

0.974

High

133738

NOP56
Nucleolar protein 56

5

9

Small-scale

0.919

High

878385

NH2L1
NHP2-like protein 1

2

9

High-throughput

0.802

High

1376980

RUVB2
RuvB-like 2

5

7

Small-scale

0.712

High

1377041

RUVB1
RuvB-like 1

4

7

Small-scale

0.683

High

348298

MYC
Myc proto-oncogene protein

4

4

High-throughput

0.676

High

1355498

NUFP1
FMR1-interacting protein NUFIP1

3

2

Small-scale

0.657

High

1301362

TGS1
Trimethylguanosine synthase

2

1

Small-scale

0.639

High

934573

CSK21
Casein kinase II subunit alpha

2

2

Small-scale

0.633

High

215397

U3IP2
U3 small nucleolar RNA-interacting protein 2

2

11

High-throughput

0.628

High

853761

IMA5
Importin subunit alpha-5

2

12

High-throughput

0.628

High

1350131

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

2

2

Small-scale

0.624

High

1042887

CUL3
Cullin-3

2

3

High-throughput

0.611

High

1076242

ZNHI3
Zinc finger HIT domain-containing protein 3

2

1

Small-scale

0.611

High

1336064

MET14
N6-adenosine-methyltransferase non-catalytic subunit

2

2

High-throughput

0.611

High

930466

UBC9
SUMO-conjugating enzyme UBC9

2

2

Small-scale

0.602

High

780356

CCNF
Cyclin-F

2

2

High-throughput

0.601

High

1347224

BCD1
Box C/D snoRNA protein 1

2

1

Small-scale

0.601

High

1347329

PIHD1
PIH1 domain-containing protein 1

2

2

Small-scale

0.601

High

229119

PRKN
E3 ubiquitin-protein ligase parkin

2

7

High-throughput

0.584

High

245118

BRD4
Bromodomain-containing protein 4

2

9

High-throughput

0.584

High

256168

OBSL1
Obscurin-like protein 1

2

3

High-throughput

0.584

High

323339

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

4

High-throughput

0.584

High

818634

SOX2
Transcription factor SOX-2

2

6

High-throughput

0.584

High

918173

H4
Histone H4

2

2

High-throughput

0.584

High

1030046

TIF1B
Transcription intermediary factor 1-beta

2

5

Small-scale

0.584

High

1059957

CHD4
Chromodomain-helicase-DNA-binding protein 4

2

8

High-throughput

0.584

High

1080505

EZH2
Histone-lysine N-methyltransferase EZH2

2

2

High-throughput

0.584

High

1116643

LARP7
La-related protein 7

2

10

High-throughput

0.584

High

1294154

DDRGK
DDRGK domain-containing protein 1

2

2

Small-scale

0.584

High

1343826

ANLN
Anillin

2

3

High-throughput

0.584

High

972275

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

2

1

High-throughput

0.571

High

1298111

CEP63
Centrosomal protein of 63 kDa

2

5

Small-scale

0.571

High

1356639

VAV3
Guanine nucleotide exchange factor VAV3

2

3

High-throughput

0.571

High

1344547

SIR7
NAD-dependent protein deacetylase sirtuin-7

2

0

Small-scale

0.559

High

1238995

POC5
Centrosomal protein POC5

2

1

Small-scale

0.552

High

238749

IMA7
Importin subunit alpha-7

1

12

High-throughput

0.536

High

403374

LA
Lupus La protein

1

6

High-throughput

0.536

High

440819

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.536

High

595481

LMNB1
Lamin-B1

1

3

High-throughput

0.536

High

601413

VDAC1
Voltage-dependent anion-selective channel protein 1

1

3

High-throughput

0.536

High

649836

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.536

High

739358

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

4

High-throughput

0.536

High

781856

MNDA
Myeloid cell nuclear differentiation antigen

1

4

High-throughput

0.536

High

801473

KI67
Proliferation marker protein Ki-67

1

3

High-throughput

0.536

High

834691

NU153
Nuclear pore complex protein Nup153

1

3

High-throughput

0.536

High

853524

IMA1
Importin subunit alpha-1

1

13

High-throughput

0.536

High

962473

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

3

High-throughput

0.536

High

1048394

SCRB2
Lysosome membrane protein 2

1

1

High-throughput

0.536

High

1060976

IMB1
Importin subunit beta-1

1

2

High-throughput

0.536

High

1086049

IF16
Gamma-interferon-inducible protein 16

1

4

High-throughput

0.536

High

1167347

BCOR
BCL-6 corepressor

1

4

Small-scale

0.536

High

1183263

COX15
Heme A synthase COX15

1

3

High-throughput

0.536

High

1202200

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

2

High-throughput

0.536

High

1224593

CDK20
Cyclin-dependent kinase 20

1

2

High-throughput

0.536

High

1305859

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

2

High-throughput

0.536

High

1332521

RPAP3
RNA polymerase II-associated protein 3

1

8

High-throughput

0.536

High

1344181

DDX21
Nucleolar RNA helicase 2

1

3

Small-scale

0.536

High

1377459

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

1

High-throughput

0.536

High

1334052

WDR76
WD repeat-containing protein 76

2

10

High-throughput

0.533

High

1348009

MCM9
DNA helicase MCM9

2

2

Small-scale

0.533

High

1169998

RHG36
Rho GTPase-activating protein 36

2

1

High-throughput

0.521

High

1328818

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

2

5

High-throughput

0.521

High

718343

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.515

High

839707

SERPH
Serpin H1

1

1

High-throughput

0.515

High

1312200

THUM2
THUMP domain-containing protein 2

1

2

High-throughput

0.515

High

1355745

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

1

High-throughput

0.515

High

116646

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

0

High-throughput

0.513

High

880434

AP1S2
AP-1 complex subunit sigma-2

1

0

High-throughput

0.513

High

175320

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

7

High-throughput

0.501

High

890903

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

4

High-throughput

0.501

High

370767

ESR1
Estrogen receptor

1

7

High-throughput

0.500

High

1063699

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.493

High

363359

FINC
Fibronectin

1

1

High-throughput

0.489

High

1300574

PSKH2
Serine/threonine-protein kinase H2

1

1

High-throughput

0.489

High

1357854

CD11A
Cyclin-dependent kinase 11A

1

2

High-throughput

0.489

High

654078

MAP4
Microtubule-associated protein 4

1

1

High-throughput

0.481

High

1357605

WDR3
WD repeat-containing protein 3

1

12

High-throughput

0.481

High

119574

LEG9
Galectin-9

1

1

High-throughput

0.479

High

123111

MEN1
Menin

1

1

High-throughput

0.479

High

125807

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

4

High-throughput

0.479

High

149448

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

160869

AURKA
Aurora kinase A

1

3

High-throughput

0.479

High

163503

XPO1
Exportin-1

1

5

High-throughput

0.479

High

179894

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

3

High-throughput

0.479

High

210384

PRC1
Protein regulator of cytokinesis 1

1

2

High-throughput

0.479

High

233700

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

233914

HBP1
HMG box-containing protein 1

1

5

High-throughput

0.479

High

268344

EED
Polycomb protein EED

1

11

High-throughput

0.479

High

298909

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

309179

KI20A
Kinesin-like protein KIF20A

1

6

High-throughput

0.479

High

317190

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

3

Small-scale

0.479

High

325948

LATS1
Serine/threonine-protein kinase LATS1

1

2

High-throughput

0.479

High

360561

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

4

Small-scale

0.479

High

375125

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

380042

MYCN
N-myc proto-oncogene protein

1

4

High-throughput

0.479

High

393396

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

1

High-throughput

0.479

High

442609

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.479

High

456018

PARP1
Poly [ADP-ribose] polymerase 1

1

5

High-throughput

0.479

High

554108

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

570205

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

591158

BTF3
Transcription factor BTF3

1

1

High-throughput

0.479

High

622553

CCND1
G1/S-specific cyclin-D1

1

1

High-throughput

0.479

High

652665

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

653039

APEX1
DNA repair nuclease/redox regulator APEX1

1

2

High-throughput

0.479

High

685127

STIP1
Stress-induced-phosphoprotein 1

1

4

High-throughput

0.479

High

707798

H2B1B
Histone H2B type 1-B

1

5

High-throughput

0.479

High

721836

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

740625

PPARG
Peroxisome proliferator-activated receptor gamma

1

7

Small-scale

0.479

High

750549

COIL
Coilin

1

2

High-throughput

0.479

High

824561

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

828064

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.479

High

902816

SUMO2
Small ubiquitin-related modifier 2

1

3

Small-scale

0.479

High

903625

WDR5
WD repeat-containing protein 5

1

7

High-throughput

0.479

High

909365

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

916979

RS6
Small ribosomal subunit protein eS6

1

3

High-throughput

0.479

High

920399

RS24
Small ribosomal subunit protein eS24

1

2

High-throughput

0.479

High

922478

RL31
Large ribosomal subunit protein eL31

1

4

High-throughput

0.479

High

935407

H31
Histone H3.1

1

8

High-throughput

0.479

High

941603

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

970084

KIF23
Kinesin-like protein KIF23

1

3

High-throughput

0.479

High

974707

MECOM
Histone-lysine N-methyltransferase MECOM

1

3

High-throughput

0.479

High

983277

UBE3A
Ubiquitin-protein ligase E3A

1

2

High-throughput

0.479

High

999238

EP300
Histone acetyltransferase p300

1

8

High-throughput

0.479

High

1018128

GRSF1
G-rich sequence factor 1

1

6

High-throughput

0.479

High

1018761

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

8

High-throughput

0.479

High

1026021

TADBP
TAR DNA-binding protein 43

1

2

High-throughput

0.479

High

1030568

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.479

High

1034147

TCOF
Treacle protein

1

2

Small-scale

0.479

High

1036228

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

1043644

CUL4B
Cullin-4B

1

3

High-throughput

0.479

High

1054691

RBM39
RNA-binding protein 39

1

4

High-throughput

0.479

High

1061102

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

4

Small-scale

0.479

High

1061701

CUL7
Cullin-7

1

1

High-throughput

0.479

High

1064277

TNIP1
TNFAIP3-interacting protein 1

1

5

High-throughput

0.479

High

1064869

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

1066916

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

1070813

RBBP5
Retinoblastoma-binding protein 5

1

7

High-throughput

0.479

High

1081453

E2F4
Transcription factor E2F4

1

1

High-throughput

0.479

High

1084942

SMN
Survival motor neuron protein

1

2

Small-scale

0.479

High

1119680

MIDN
Midnolin

1

1

High-throughput

0.479

High

1136370

RC3H1
Roquin-1

1

4

High-throughput

0.479

High

1156432

ZN746
Zinc finger protein 746

1

3

High-throughput

0.479

High

1201785

ZCH18
Zinc finger CCCH domain-containing protein 18

1

3

High-throughput

0.479

High

1221860

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

1222650

SLX4
Structure-specific endonuclease subunit SLX4

1

3

High-throughput

0.479

High

1235280

NGEF
Ephexin-1

1

3

High-throughput

0.479

High

1235718

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

3

High-throughput

0.479

High

1244580

NUP43
Nucleoporin Nup43

1

11

High-throughput

0.479

High

1246506

WDR36
WD repeat-containing protein 36

1

12

High-throughput

0.479

High

1256495

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

High-throughput

0.479

High

1261454

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.479

High

1264216

DNJC9
DnaJ homolog subfamily C member 9

1

1

High-throughput

0.479

High

1267284

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

1269988

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

1281498

FBXW7
F-box/WD repeat-containing protein 7

1

4

High-throughput

0.479

High

1285798

CHCH1
Small ribosomal subunit protein mS37

1

1

High-throughput

0.479

High

1286499

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

1286761

CHM4C
Charged multivesicular body protein 4c

1

3

High-throughput

0.479

High

1288400

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

6

High-throughput

0.479

High

1290907

TRI11
E3 ubiquitin-protein ligase TRIM11

1

4

Small-scale

0.479

High

1292315

AURKB
Aurora kinase B

1

3

High-throughput

0.479

High

1301012

CIC
Protein capicua homolog

1

5

High-throughput

0.479

High

1304198

RING2
E3 ubiquitin-protein ligase RING2

1

5

High-throughput

0.479

High

1313223

DDX23
Probable ATP-dependent RNA helicase DDX23

1

3

High-throughput

0.479

High

1315917

FACD2
Fanconi anemia group D2 protein

1

4

High-throughput

0.479

High

1316942

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

6

High-throughput

0.479

High

1319146

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.479

High

1326465

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

3

High-throughput

0.479

High

1326797

WWTR1
WW domain-containing transcription regulator protein 1

1

5

High-throughput

0.479

High

1327160

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

High-throughput

0.479

High

1328317

CCDC8
Coiled-coil domain-containing protein 8

1

5

High-throughput

0.479

High

1330199

TXNIP
Thioredoxin-interacting protein

1

4

Small-scale

0.479

High

1333828

ECT2
Protein ECT2

1

5

High-throughput

0.479

High

1335051

PRD16
Histone-lysine N-methyltransferase PRDM16

1

3

High-throughput

0.479

High

1335251

RC3H2
Roquin-2

1

6

High-throughput

0.479

High

1336080

ARGAL
Rho guanine nucleotide exchange factor 10-like protein

1

3

High-throughput

0.479

High

1342853

BRD7
Bromodomain-containing protein 7

1

7

High-throughput

0.479

High

1345467

RAD18
E3 ubiquitin-protein ligase RAD18

1

2

High-throughput

0.479

High

1346285

DCA13
DDB1- and CUL4-associated factor 13

1

9

Small-scale

0.479

High

1354936

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1357210

FZR1
Fizzy-related protein homolog

1

8

High-throughput

0.479

High

1377458

ZN330
Zinc finger protein 330

1

2

High-throughput

0.479

High

295695

RMP
Unconventional prefoldin RPB5 interactor 1

1

0

Small-scale

0.458

High

504992

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

719250

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

968015

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1260966

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

1274369

MED12
Mediator of RNA polymerase II transcription subunit 12

1

0

High-throughput

0.458

High

1300126

CDK15
Cyclin-dependent kinase 15

1

0

High-throughput

0.458

High

1308516

B9D2
B9 domain-containing protein 2

1

0

High-throughput

0.458

High

1316835

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

1334449

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

48753

MED19
Mediator of RNA polymerase II transcription subunit 19

1

1

High-throughput

0.445

High

402655

JUN
Transcription factor Jun

1

4

High-throughput

0.445

High

854009

NCBP2
Nuclear cap-binding protein subunit 2

1

6

High-throughput

0.445

High

931497

YBOX1
Y-box-binding protein 1

1

4

High-throughput

0.445

High

967100

XPC
DNA repair protein complementing XP-C cells

1

3

High-throughput

0.445

High

1032701

CTBP1
C-terminal-binding protein 1

1

3

High-throughput

0.445

High

1044296

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.445

High

1057736

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.445

High

1083714

TAF9
Transcription initiation factor TFIID subunit 9

1

1

Small-scale

0.445

High

1130747

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

1334616

LN28A
Protein lin-28 homolog A

1

5

High-throughput

0.445

High

1347432

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

2

High-throughput

0.445

High

283063

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

8

High-throughput

0.437

High

330025

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

385764

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

391978

H2A1B
Histone H2A type 1-B/E

1

2

High-throughput

0.437

High

1062717

EMC2
ER membrane protein complex subunit 2

1

4

High-throughput

0.437

High

1067207

BRD3
Bromodomain-containing protein 3

1

11

High-throughput

0.437

High

1074779

SSXT
Protein SSXT

1

1

High-throughput

0.437

High

1172361

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.437

High

1189077

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1331683

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1357017

HECD1
E3 ubiquitin-protein ligase HECTD1

1

5

High-throughput

0.437

High

1377460

MAFB
Transcription factor MafB

1

4

High-throughput

0.437

High

1347158

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.426

High

1347860

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.426

High

1377107

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

831827

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.408

High

1242903

HIPK4
Homeodomain-interacting protein kinase 4

1

3

High-throughput

0.407

High

376346

ANXA1
Annexin A1

1

0

Small-scale

0.391

High

1234640

NOPC1
NOP protein chaperone 1

2

0

High-throughput

0.324

High

147121

NEMP1
Nuclear envelope integral membrane protein 1

1

0

High-throughput

0.279

Low

856501

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

484400

SCHI1
Schwannomin-interacting protein 1

1

0

High-throughput

0.249

Low

1218224

CC103
Coiled-coil domain-containing protein 103

1

0

High-throughput

0.249

Low

1229881

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024