HitPredict

Interactor 1: H0YKT8 (H0YKT8)
Proteasome subunit beta
Gene: PSMA4

Interactor 2: PSB7 (Q99436)
Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z)
Gene: PSMB7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Pr_beta_C~Proteasome, Proteasome~Proteasome
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Hs			1 277
+	Hs
		637732 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB7_HUMAN (1-277): 2.34e-107: 314: 100.00
+	Hs
		637640 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB10_HUMAN (7-276): 4.71e-95: 282: 56.67
+	Dm
		184454 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		O17311_DROME (10-277): 5.47e-92: 274: 64.07
+	Dm
		771324 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q9VUJ1_DROME (10-277): 2.75e-87: 262: 64.82
+	Dm
		771302 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q8T8V8_DROME (15-225): 1.43e-83: 254: 27.15
+	Hs
		637631 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSA5_HUMAN (13-240): 3.35e-81: 246: 18.67
+	Ss
		94704 F2Z5L7_PIG (1-177): 5.77e-76: 229: 29.21		F2Z5K2_PIG (13-240): 3.35e-81: 246: 18.67
+	Hs
		637629 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB8_HUMAN (31-243): 3.86e-78: 239: 24.30
+	Dm
		771294 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		Q7K148_DROME (5-251): 4.24e-78: 239: 26.91
+	Dm
		771303 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PSA5_DROME (13-242): 1.22e-78: 239: 17.14
+	Hs
		637633 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB6_HUMAN (41-229): 3.57e-76: 233: 31.58
+	Hs
		637634 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB5_HUMAN (42-243): 1.28e-74: 230: 26.11
+	Ss
		94705 F2Z5L7_PIG (1-177): 5.77e-76: 229: 29.21		G3DRF8_PIG (36-229): 1.12e-75: 232: 30.77
+	Hs
		638067 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSA5_HUMAN (13-240): 3.35e-81: 246: 18.67
+	Hs
		638065 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSB8_HUMAN (31-243): 3.86e-78: 239: 24.30
+	Ss
		94582 F2Z5L7_PIG (1-177): 5.77e-76: 229: 29.21		F1SBA5_PIG (20-239): 5.79e-71: 220: 18.78
+	Hs
		638069 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSB6_HUMAN (41-229): 3.57e-76: 233: 31.58
+	Dm
		47598 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		A0AQH0_DROME (42-227): 1.55e-22: 94.4: 29.41
+	Hs
		637630 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSB9_HUMAN (42-227): 9.71e-21: 89.7: 29.41
+	Hs
		638066 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSB9_HUMAN (42-227): 9.71e-21: 89.7: 29.41