HitPredict

Interactor 1: TRPA1 (Q18297)
Transient receptor potential cation channel subfamily A member 1 homolog
Gene: trpa-1

Interactor 2: TRPA1 (Q18297)
Transient receptor potential cation channel subfamily A member 1 homolog
Gene: trpa-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	25855297
Identification Methods	molecular sieving
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ank_2~Ank_2, Ion_trans~Ion_trans
Common GO terms	GO:0005216 - monoatomic ion channel activity GO:0005886 - plasma membrane GO:0043025 - neuronal cell body GO:0050896 - response to stimulus GO:0097730 - non-motile cilium
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1211 Ce			1 1211
+	Mm
		103591 ANK3_MOUSE (91-831): 1.82e-147: 491: 18.57		ANK3_MOUSE (91-831): 1.82e-147: 491: 18.57
+	Mm
		103608 ANK3_MOUSE (91-831): 1.82e-147: 491: 18.57		ANK2_MOUSE (1-398): 6.32e-94: 335: 19.10
+	Hs
		1329533 TNKS2_HUMAN (2-418): 5.16e-84: 300: 19.44		TNKS2_HUMAN (2-418): 5.16e-84: 300: 19.44
+	Hs
		274702 TRPA1_HUMAN (1-528): 4.5e-64: 240: 15.85		TRPA1_HUMAN (1-528): 4.5e-64: 240: 15.85
+	Hs
		166969 ANR44_HUMAN (134-817): 1.78e-122: 405: 18.86		ANR28_HUMAN (1-104): 2.19e-10: 67.2: 21.30
+	Dr
		1137612 Q5UM15_DANRE (1-461): 3.51e-62: 233: 17.81		Q5UM15_DANRE (1-461): 3.51e-62: 233: 17.81
+	Dm
		90295 E0A9E1_DROME (299-817): 5.55e-61: 232: 13.46		E0A9E1_DROME (299-817): 5.55e-61: 232: 13.46
+	Mm
		1206854 TRPA1_MOUSE (3-488): 1.15e-60: 229: 15.49		TRPA1_MOUSE (3-488): 1.15e-60: 229: 15.49
+	Hs
		166971 ANR52_HUMAN (6-618): 1.17e-106: 363: 19.68		ANR28_HUMAN (1-104): 2.19e-10: 67.2: 21.30
+	Hs
		166913 ANK2_HUMAN (1-398): 1.95e-94: 336: 19.10		ANR28_HUMAN (1-104): 2.19e-10: 67.2: 21.30
+	Hs
		166919 ANK3_HUMAN (319-847): 8.49e-89: 319: 17.79		ANR28_HUMAN (1-104): 2.19e-10: 67.2: 21.30
+	Hs
		167036 ANR50_HUMAN (325-826): 6.38e-88: 314: 19.92		ANR28_HUMAN (1-104): 2.19e-10: 67.2: 21.30
+	Hs
		167014 TNKS2_HUMAN (2-418): 5.16e-84: 300: 19.44		ANR28_HUMAN (1-104): 2.19e-10: 67.2: 21.30
+	Dr
		1137611 Q5UM14_DANRE (1-229): 3.2e-29: 128: 20.35		Q5UM14_DANRE (1-229): 3.2e-29: 128: 20.35
+	Hs
		310030 TNKS1_HUMAN (9-140): 8.82e-29: 127: 25.37		TNKS1_HUMAN (9-140): 8.82e-29: 127: 25.37
+	Rn
		1164189 TRPA1_RAT (2-277): 2.67e-27: 122: 15.84		TRPA1_RAT (2-277): 2.67e-27: 122: 15.84
+	Hs
		257652 ANKH1_HUMAN (531-795): 4.99e-30: 132: 17.95		ANR17_HUMAN (2-72): 2.26e-13: 77.6: 8.45
+	Hs
		166869 TNKS1_HUMAN (9-140): 8.82e-29: 127: 25.37		ANR28_HUMAN (1-104): 2.19e-10: 67.2: 21.30
+	Rn
		1351669 TRPV6_RAT (261-496): 5.23e-17: 88.7: 17.32		TRPV6_RAT (261-496): 5.23e-17: 88.7: 17.32