HitPredict

Interactor 1: ELAV2 (Q12926)
ELAV-like protein 2 (ELAV-like neuronal protein 1) (Hu-antigen B) (HuB) (Nervous system-specific RNA-binding protein Hel-N1)
Gene: ELAVL2

Interactor 2: ELAV3 (Q14576)
ELAV-like protein 3 (Hu-antigen C) (HuC) (Paraneoplastic cerebellar degeneration-associated antigen) (Paraneoplastic limbic encephalitis antigen 21)
Gene: ELAVL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:1990904 - ribonucleoprotein complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 359 Hs			1 367
+	Hs
		686613 ELAV2_HUMAN (1-359): 4.91e-104: 311: 100.00		ELAV4_HUMAN (1-367): 6.94e-97: 295: 76.41
+	Xl
		1362166 ELAV2_XENLA (1-359): 3.42e-97: 295: 91.16		ELAV2_XENLA (4-367): 1.91e-96: 293: 75.47
+	Dm
		119988 M9PBZ2_DROME (34-358): 7.02e-84: 270: 59.88		Q9VYI0_DROME (13-365): 3.48e-78: 246: 52.83
+	Dm
		119977 M9PBZ2_DROME (34-358): 7.02e-84: 270: 59.88		ELAV_DROME (17-365): 1.52e-75: 243: 47.38
+	Dm
		599464 ELAV_DROME (19-357): 2.11e-75: 242: 50.42		Q9VYI0_DROME (13-365): 3.48e-78: 246: 52.83
+	Dm
		599459 ELAV_DROME (19-357): 2.11e-75: 242: 50.42		ELAV_DROME (17-365): 1.52e-75: 243: 47.38
+	Hs
		1090216 ELAV2_HUMAN (1-359): 4.91e-104: 311: 100.00		PABP4_HUMAN (23-308): 5e-47: 170: 19.49
+	Hs
		1090232 ELAV2_HUMAN (1-359): 4.91e-104: 311: 100.00		ELAV1_HUMAN (2-207): 9.42e-37: 137: 16.28
+	Hs
		550250 ELAV2_HUMAN (1-359): 4.91e-104: 311: 100.00		PABP1_HUMAN (274-365): 9.55e-21: 95.5: 18.48
+	Dm
		620682 SXL_DROME (20-218): 1.61e-55: 187: 44.66		SXL_DROME (25-218): 8.02e-52: 177: 44.50
+	Dm
		119975 M9PBZ2_DROME (34-358): 7.02e-84: 270: 59.88		M9PBZ2_DROME (2-103): 3.4e-18: 88.2: 31.37
+	Hs
		1102095 PABP3_HUMAN (115-358): 1.09e-42: 158: 20.51		PABP4_HUMAN (23-308): 5e-47: 170: 19.49
+	Sc
		403283 PABP_YEAST (7-286): 1.55e-42: 157: 22.44		PABP_YEAST (3-294): 1.88e-44: 162: 21.73
+	Zm
		8282 A0A1D6ELH4_MAIZE (40-277): 2.75e-42: 157: 19.32		A0A1D6ELH4_MAIZE (3-285): 1.88e-43: 161: 20.33
+	Hs
		550311 PAP1L_HUMAN (2-279): 1.21e-45: 166: 17.76		PABP1_HUMAN (274-365): 9.55e-21: 95.5: 18.48
+	Hs
		1197178 PAP1L_HUMAN (2-279): 1.21e-45: 166: 17.76		PABP3_HUMAN (274-365): 1.34e-18: 89.3: 16.30
+	Hs
		550464 PABP3_HUMAN (115-358): 1.09e-42: 158: 20.51		PABP1_HUMAN (274-365): 9.55e-21: 95.5: 18.48