HitPredict

Interactor 1: Q1CZ93 (Q1CZ93)
DNA-binding response regulator, LuxR family
Gene: MXAN_6149

Interactor 2: Q1D033 (Q1D033)
Sigma-54 dependent DNA-binding response regulator
Gene: MXAN_5853

Species: Myxococcus xanthus DK 1622

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	18442170
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	GerE~Response_reg, Response_reg~Response_reg, Response_reg~Sigma54_activat
Common GO terms	GO:0000160 - phosphorelay signal transduction system GO:0003677 - DNA binding GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 218 Mx			1 460
+	Ec
		985803 ATOC_ECOLI (2-218): 8.69e-52: 175: 19.56		ATOC_ECOLI (2-458): 6.24e-175: 499: 41.90
+	Mx
		1091406 Q1D8M8_MYXXD (3-213): 3.35e-52: 170: 19.01		Q1D033_MYXXD (1-460): 2.57e-172: 493: 100.00
+	Ec
		468719 NTRC_ECOLI (3-218): 9.91e-53: 177: 18.64		NTRC_ECOLI (4-456): 1.22e-164: 474: 42.34
+	Mx
		1091425 Q1D1K9_MYXXD (2-215): 1.03e-58: 186: 21.97		Q1D0A2_MYXXD (3-457): 2.49e-150: 438: 40.56
+	Mx
		1091395 Q1CZP3_MYXXD (2-217): 2.27e-52: 170: 18.67		Q1D0A2_MYXXD (3-457): 2.49e-150: 438: 40.56
+	Ec
		469022 ATOC_ECOLI (2-218): 8.69e-52: 175: 19.56		GLRR_ECOLI (2-457): 8.6e-149: 432: 35.65
+	Mx
		1091289 Q1D8M8_MYXXD (3-213): 3.35e-52: 170: 19.01		Q1CWG7_MYXXD (4-459): 2.72e-146: 427: 41.95
+	Ec
		468921 PHOB_ECOLI (2-214): 3.47e-60: 190: 19.20		PHOB_ECOLI (3-212): 3.8e-44: 156: 23.64
+	Ec
		465608 PHOB_ECOLI (2-214): 3.47e-60: 190: 19.20		OMPR_ECOLI (3-206): 1.08e-41: 150: 22.64
+	Mx
		1091446 Q1D8M8_MYXXD (3-213): 3.35e-52: 170: 19.01		Q1D1K9_MYXXD (3-202): 3.15e-45: 159: 23.67
+	Ss
		937544 P73864_SYNY3 (1-213): 2.28e-54: 175: 30.88		P72948_SYNY3 (1-202): 4.27e-43: 154: 19.34
+	Mx
		1091499 Q1D4T4_MYXXD (3-215): 5.54e-55: 176: 21.49		Q1D4T4_MYXXD (4-206): 2.21e-42: 151: 16.75
+	Ec
		940185 HPRR_ECOLI (1-216): 8.94e-54: 173: 19.56		HPRR_ECOLI (2-202): 5.09e-43: 152: 20.19
+	Ss
		1122357 RPPA_SYNY3 (1-214): 1.91e-50: 165: 20.60		RPPA_SYNY3 (2-202): 1.11e-43: 155: 17.54
+	Ec
		465604 OMPR_ECOLI (2-217): 2.95e-51: 167: 16.38		OMPR_ECOLI (3-206): 1.08e-41: 150: 22.64
+	Ec
		621089 PHOP_ECOLI (1-214): 3.21e-52: 169: 19.73		PHOP_ECOLI (2-172): 5.67e-37: 137: 25.71
+	Ec
		467563 CUSR_ECOLI (1-214): 1.28e-53: 173: 18.83		CUSR_ECOLI (2-119): 3.38e-33: 127: 32.79
+	Ec
		467567 HPRR_ECOLI (1-216): 8.94e-54: 173: 19.56		CUSR_ECOLI (2-119): 3.38e-33: 127: 32.79