Protein: FOXB1
Forkhead box protein B1 (Transcription factor FKH-5)

Gene: FOXB1
Organism: Homo sapiens
Interactions: 136
UniProt ID: Q99853

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001655 - urogenital system development
GO:0001756 - somitogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1407751

FOXB1
Forkhead box protein B1

1

18

High-throughput

0.575

High

572160

TRI27
Zinc finger protein RFP

1

3

High-throughput

0.573

High

1277369

NT2NA
Notch homolog 2 N-terminal-like protein A

1

2

High-throughput

0.573

High

1274044

PHF5A
PHD finger-like domain-containing protein 5A

1

1

High-throughput

0.541

High

123171

DX39A
ATP-dependent RNA helicase DDX39A

1

12

High-throughput

0.536

High

129368

MEN1
Menin

1

4

High-throughput

0.536

High

215871

AN32C
Putative uncharacterized protein ANP32CP

1

4

High-throughput

0.536

High

243715

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

20

High-throughput

0.536

High

254215

CTND1
Catenin delta-1

1

8

High-throughput

0.536

High

277795

H2AY
Core histone macro-H2A.1

1

6

High-throughput

0.536

High

286045

SF3B1
Splicing factor 3B subunit 1

1

11

High-throughput

0.536

High

320008

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.536

High

326001

UBR5
E3 ubiquitin-protein ligase UBR5

1

7

High-throughput

0.536

High

334084

SMC2
Structural maintenance of chromosomes protein 2

1

20

High-throughput

0.536

High

414497

P53
Cellular tumor antigen p53

1

12

High-throughput

0.536

High

431605

AP2A
Transcription factor AP-2-alpha

1

2

High-throughput

0.536

High

589517

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.536

High

616354

RCC1
Regulator of chromosome condensation

1

6

High-throughput

0.536

High

617733

XRCC1
DNA repair protein XRCC1

1

2

High-throughput

0.536

High

675647

TYY1
Transcriptional repressor protein YY1

1

6

High-throughput

0.536

High

714950

EF1D
Elongation factor 1-delta

1

3

High-throughput

0.536

High

724945

HXA10
Homeobox protein Hox-A10

1

20

High-throughput

0.536

High

764992

CTNB1
Catenin beta-1

1

9

High-throughput

0.536

High

771604

HXD13
Homeobox protein Hox-D13

1

20

High-throughput

0.536

High

854727

RAGP1
Ran GTPase-activating protein 1

1

5

High-throughput

0.536

High

890577

RBP2
E3 SUMO-protein ligase RanBP2

1

3

High-throughput

0.536

High

892611

DNLI3
DNA ligase 3

1

5

High-throughput

0.536

High

892721

DNLI4
DNA ligase 4

1

5

High-throughput

0.536

High

903017

NOVA1
RNA-binding protein Nova-1

1

18

High-throughput

0.536

High

911356

IMA5
Importin subunit alpha-5

1

5

High-throughput

0.536

High

913804

ZN131
Zinc finger protein 131

1

3

High-throughput

0.536

High

914114

HXK2
Hexokinase-2

1

6

High-throughput

0.536

High

929826

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

4

High-throughput

0.536

High

937327

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

13

High-throughput

0.536

High

941534

CTBP2
C-terminal-binding protein 2

1

9

High-throughput

0.536

High

1032777

SATB1
DNA-binding protein SATB1

1

20

High-throughput

0.536

High

1047084

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

3

High-throughput

0.536

High

1047857

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.536

High

1048077

TLE3
Transducin-like enhancer protein 3

1

20

High-throughput

0.536

High

1048176

TLE4
Transducin-like enhancer protein 4

1

20

High-throughput

0.536

High

1060480

DPOE1
DNA polymerase epsilon catalytic subunit A

1

6

High-throughput

0.536

High

1088735

SF3A3
Splicing factor 3A subunit 3

1

2

High-throughput

0.536

High

1101886

SKP2
S-phase kinase-associated protein 2

1

6

High-throughput

0.536

High

1121142

UBE4A
Ubiquitin conjugation factor E4 A

1

5

High-throughput

0.536

High

1130163

SMC1A
Structural maintenance of chromosomes protein 1A

1

20

High-throughput

0.536

High

1137256

CND1
Condensin complex subunit 1

1

4

High-throughput

0.536

High

1168874

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

15

High-throughput

0.536

High

1177629

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

7

High-throughput

0.536

High

1217184

RIF1
Telomere-associated protein RIF1

1

7

High-throughput

0.536

High

1219333

ECM29
Proteasome adapter and scaffold protein ECM29

1

15

High-throughput

0.536

High

1226647

E4F1
Transcription factor E4F1

1

2

High-throughput

0.536

High

1279225

WAPL
Wings apart-like protein homolog

1

1

High-throughput

0.536

High

1280441

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

4

High-throughput

0.536

High

1286786

KAISO
Transcriptional regulator Kaiso

1

6

High-throughput

0.536

High

1288844

ZFHX4
Zinc finger homeobox protein 4

1

7

High-throughput

0.536

High

1292509

CHD1L
Chromodomain-helicase-DNA-binding protein 1-like

1

20

High-throughput

0.536

High

1309364

ARI3B
AT-rich interactive domain-containing protein 3B

1

20

High-throughput

0.536

High

1323138

CCAR2
Cell cycle and apoptosis regulator protein 2

1

2

High-throughput

0.536

High

1323271

SIX5
Homeobox protein SIX5

1

17

High-throughput

0.536

High

1325382

STAG2
Cohesin subunit SA-2

1

2

High-throughput

0.536

High

1393931

FUBP3
Far upstream element-binding protein 3

1

15

High-throughput

0.536

High

1394771

HIC2
Hypermethylated in cancer 2 protein

1

5

High-throughput

0.536

High

1396341

ZFR
Zinc finger RNA-binding protein

1

10

High-throughput

0.536

High

1407752

ARI3A
AT-rich interactive domain-containing protein 3A

1

20

High-throughput

0.536

High

1407753

DUS9
Dual specificity protein phosphatase 9

1

1

High-throughput

0.536

High

1407761

SALL1
Sal-like protein 1

1

11

High-throughput

0.536

High

1407762

SMC4
Structural maintenance of chromosomes protein 4

1

20

High-throughput

0.536

High

1407764

ZBT40
Zinc finger and BTB domain-containing protein 40

1

1

High-throughput

0.536

High

1407768

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

1

5

High-throughput

0.536

High

1407769

PARP2
Poly [ADP-ribose] polymerase 2

1

3

High-throughput

0.536

High

1407771

RALY
RNA-binding protein Raly

1

11

High-throughput

0.536

High

1407773

NOVA2
RNA-binding protein Nova-2

1

18

High-throughput

0.536

High

1407775

SATB2
DNA-binding protein SATB2

1

20

High-throughput

0.536

High

1407776

PA2G4
Proliferation-associated protein 2G4

1

2

High-throughput

0.536

High

1407777

SMC3
Structural maintenance of chromosomes protein 3

1

20

High-throughput

0.536

High

1407778

NOC2L
Nucleolar complex protein 2 homolog

1

2

High-throughput

0.536

High

950638

KR108
Keratin-associated protein 10-8

1

6

High-throughput

0.523

High

1146117

K1H1
Keratin, type I cuticular Ha1

1

3

High-throughput

0.523

High

1230224

K1C40
Keratin, type I cytoskeletal 40

1

3

High-throughput

0.523

High

1359896

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

0

High-throughput

0.513

High

1407755

PAXX
Protein PAXX

1

0

High-throughput

0.513

High

1407759

NHEJ1
Non-homologous end-joining factor 1

1

0

High-throughput

0.513

High

173746

BTAF1
TATA-binding protein-associated factor 172

1

20

High-throughput

0.489

High

354382

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

5

High-throughput

0.489

High

359866

DYR
Dihydrofolate reductase

1

1

High-throughput

0.489

High

477843

RM03
Large ribosomal subunit protein uL3m

1

4

High-throughput

0.489

High

576824

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.489

High

622257

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

2

High-throughput

0.489

High

687855

SYVC
Valine--tRNA ligase

1

20

High-throughput

0.489

High

769000

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.489

High

834514

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

20

High-throughput

0.489

High

868237

SYQ
Glutamine--tRNA ligase

1

1

High-throughput

0.489

High

914161

HXK3
Hexokinase-3

1

6

High-throughput

0.489

High

922004

COPA
Coatomer subunit alpha

1

5

High-throughput

0.489

High

1060909

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

6

High-throughput

0.489

High

1085273

NU160
Nuclear pore complex protein Nup160

1

2

High-throughput

0.489

High

1085818

TF3C1
General transcription factor 3C polypeptide 1

1

4

High-throughput

0.489

High

1111481

IQGA2
Ras GTPase-activating-like protein IQGAP2

1

5

High-throughput

0.489

High

1122326

SCRIB
Protein scribble homolog

1

4

High-throughput

0.489

High

1124029

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

2

High-throughput

0.489

High

1135463

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

1

6

High-throughput

0.489

High

1136057

CND2
Condensin complex subunit 2

1

1

High-throughput

0.489

High

1152845

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

5

High-throughput

0.489

High

1207117

SYAM
Alanine--tRNA ligase, mitochondrial

1

2

High-throughput

0.489

High

1244578

SYDM
Aspartate--tRNA ligase, mitochondrial

1

6

High-throughput

0.489

High

1347049

G45IP
Large ribosomal subunit protein mL64

1

3

High-throughput

0.489

High

1356442

TF3C2
General transcription factor 3C polypeptide 2

1

2

High-throughput

0.489

High

1363828

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

4

High-throughput

0.489

High

1365892

NU205
Nuclear pore complex protein Nup205

1

5

High-throughput

0.489

High

1368745

SYMPK
Symplekin

1

5

High-throughput

0.489

High

1382279

RM24
Large ribosomal subunit protein uL24m

1

1

High-throughput

0.489

High

1387930

RM38
Large ribosomal subunit protein mL38

1

3

High-throughput

0.489

High

1407758

HEAT1
HEAT repeat-containing protein 1

1

5

High-throughput

0.489

High

1407760

RT30
Large ribosomal subunit protein mL65

1

1

High-throughput

0.489

High

1407765

NSMA3
Sphingomyelin phosphodiesterase 4

1

7

High-throughput

0.489

High

1407767

SYLC
Leucine--tRNA ligase, cytoplasmic

1

20

High-throughput

0.489

High

1407772

TF3C4
General transcription factor 3C polypeptide 4

1

5

High-throughput

0.489

High

1407774

COG5
Conserved oligomeric Golgi complex subunit 5

1

1

High-throughput

0.489

High

1407779

TF3C5
General transcription factor 3C polypeptide 5

1

4

High-throughput

0.489

High

1407780

TF3C3
General transcription factor 3C polypeptide 3

1

12

High-throughput

0.489

High

1407781

COPG1
Coatomer subunit gamma-1

1

2

High-throughput

0.489

High

1289575

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1407770

XPO7
Exportin-7

1

7

High-throughput

0.479

High

949973

KR103
Keratin-associated protein 10-3

1

6

High-throughput

0.439

High

76019

B4DEF8
Large ribosomal subunit protein mL45

1

5

High-throughput

0.437

High

1042062

LMNB2
Lamin-B2

1

4

High-throughput

0.437

High

1311597

SUGP2
SURP and G-patch domain-containing protein 2

1

3

High-throughput

0.437

High

1407754

RM45
Large ribosomal subunit protein mL45

1

5

High-throughput

0.407

High

921758

COPB
Coatomer subunit beta

1

0

High-throughput

0.282

High

1196145

RM51
Large ribosomal subunit protein mL51

1

0

High-throughput

0.279

Low

1328265

RM50
Large ribosomal subunit protein mL50

1

0

High-throughput

0.279

Low

1407756

RM20
Large ribosomal subunit protein bL20m

1

0

High-throughput

0.279

Low

1407757

RM18
Large ribosomal subunit protein uL18m

1

0

High-throughput

0.279

Low

1407763

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.279

Low

1407766

RM27
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025