HitPredict

Interactor 1: Q1D6S5 (Q1D6S5)
histidine kinase (EC 2.7.13.3)
Gene: MXAN_3451

Interactor 2: Q1D6S6 (Q1D6S6)
DNA-binding heavy metal response regulator
Gene: MXAN_3450

Species: Myxococcus xanthus DK 1622

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	18442170
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HATPase_c~Response_reg, HisKA~Response_reg
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 452 Mx			1 226
+	Mx
		1091534 Q1D6S5_MYXXD (1-452): 1.12e-99: 307: 100.00		Q1D8M8_MYXXD (3-222): 5.42e-73: 223: 37.39
+	Mx
		1091479 Q1D333_MYXXD (94-451): 3.06e-65: 218: 21.60		Q1DCL7_MYXXD (3-221): 2.04e-78: 236: 33.04
+	Ec
		467568 CUSS_ECOLI (33-451): 1.88e-70: 232: 21.69		CUSR_ECOLI (1-222): 1.32e-71: 219: 40.18
+	Mx
		1091453 Q1D1W0_MYXXD (13-448): 4.54e-67: 224: 22.39		Q1D6S6_MYXXD (1-226): 1.88e-74: 226: 100.00
+	Mt
		958576 PRRB_MYCTU (123-451): 2.34e-75: 244: 30.00		PRRA_MYCTU (16-223): 5.43e-66: 205: 41.51
+	Mx
		1091457 Q1D1W0_MYXXD (13-448): 4.54e-67: 224: 22.39		Q1D8M8_MYXXD (3-222): 5.42e-73: 223: 37.39
+	Mx
		1091472 Q1D333_MYXXD (94-451): 3.06e-65: 218: 21.60		Q1D6S6_MYXXD (1-226): 1.88e-74: 226: 100.00
+	Mx
		1091475 Q1D333_MYXXD (94-451): 3.06e-65: 218: 21.60		Q1D8M8_MYXXD (3-222): 5.42e-73: 223: 37.39
+	Mx
		1091444 Q1D333_MYXXD (94-451): 3.06e-65: 218: 21.60		Q1D1K9_MYXXD (2-224): 2.63e-72: 221: 40.89
+	Mx
		1091452 Q1D1W0_MYXXD (13-448): 4.54e-67: 224: 22.39		Q1D4T4_MYXXD (3-222): 2.04e-69: 213: 32.31
+	Mx
		1091438 Q1D1K8_MYXXD (118-448): 4.89e-62: 210: 28.66		Q1D6S6_MYXXD (1-226): 1.88e-74: 226: 100.00
+	Mx
		1091248 Q1CVV2_MYXXD (68-449): 6.6e-61: 214: 20.66		Q1D1K9_MYXXD (2-224): 2.63e-72: 221: 40.89
+	Mx
		1091371 Q1D333_MYXXD (94-451): 3.06e-65: 218: 21.60		Q1CYI6_MYXXD (3-225): 6.42e-67: 207: 38.50
+	Mx
		1091469 Q1D333_MYXXD (94-451): 3.06e-65: 218: 21.60		Q1D334_MYXXD (2-222): 7.79e-67: 207: 34.96
+	Ec
		439404 CREC_ECOLI (84-449): 9.54e-63: 212: 22.79		CREB_ECOLI (5-221): 1.1e-68: 211: 33.64
+	Cv
		1308003 Q9A913_CAUVC (47-451): 1.25e-62: 211: 23.90		Q9A912_CAUVC (2-226): 7.02e-63: 198: 28.33
+	Mx
		1091459 Q1D1W0_MYXXD (13-448): 4.54e-67: 224: 22.39		Q1DBP1_MYXXD (1-223): 2.19e-57: 183: 35.11
+	Cv
		1307990 Q9AAR6_CAUVC (87-449): 1.27e-65: 220: 27.60		Q9A223_CAUVC (13-222): 1.95e-58: 186: 29.11
+	Ec
		752005 TORS_ECOLI (149-452): 6.53e-64: 223: 21.90		TORR_ECOLI (2-225): 1.11e-56: 181: 24.89
+	Ec
		576107 RSTB_ECOLI (166-450): 6.69e-62: 209: 26.37		RSTA_ECOLI (3-224): 1.34e-58: 186: 27.23