Interactor 1: ASIC1 (Q1XA76)
Acid-sensing ion channel 1 (ASIC1) (Amiloride-sensitive cation channel 2, neuronal)
Gene: ASIC1

Interactor 2: ASIC1 (Q1XA76)
Acid-sensing ion channel 1 (ASIC1) (Amiloride-sensitive cation channel 2, neuronal)
Gene: ASIC1

Species: Gallus gallus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.910

The method score is based on:

Property Details
Experiments 17882215, 19641589, 22842900, 29513651
Identification Methods x-ray crystallography, molecular sieving, cross-linking study, light scattering, 3D electron microscopy
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ASC~ASC
Common GO terms GO:0005886 - plasma membrane
GO:0015280 - ligand-gated sodium channel activity
GO:0035725 - sodium ion transmembrane transport
GO:0070207 - protein homotrimerization
GO:0071467 - cellular response to pH
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 527
Gg

1 527
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024