HitPredict

Interactor 1: DDB1 (Q21554)
DNA damage-binding protein 1 (Damage-specific DNA-binding protein 1)
Gene: ddb-1

Interactor 2: Q21934 (Q21934)
WD_REPEATS_REGION domain-containing protein
Gene: CELE_R11D1.1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.40	1.00	0.637

Property	Details
Experiments	14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CPSF_A~WD40, MMS1_N~WD40
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1134 Ce			1 622
+	Ce
		1094298 DDB1_CAEEL (1-1134): 0: 1141: 100.00		Q7JLF4_CAEEL (1-622): 4.45e-127: 389: 99.84
+	Mm
		1112258 DDB1_MOUSE (1-1134): 0: 1212: 36.43		DCAF5_MOUSE (29-400): 1.05e-94: 313: 28.84
+	Hs
		1082337 DDB1_HUMAN (1-1134): 0: 1209: 36.43		DCAF5_HUMAN (29-400): 7.47e-95: 313: 28.57
+	Mm
		1112284 DDB1_MOUSE (1-1134): 0: 1212: 36.43		DCAF8_MOUSE (12-450): 7e-89: 289: 19.08
+	Hs
		1082225 DDB1_HUMAN (1-1134): 0: 1209: 36.43		DCAF8_HUMAN (12-450): 1.52e-88: 288: 19.08
+	Hs
		473600 DDB1_HUMAN (1-1134): 0: 1209: 36.43		DC8L2_HUMAN (12-453): 4.11e-85: 280: 18.52
+	Mm
		1112266 DDB1_MOUSE (1-1134): 0: 1212: 36.43		WDR82_MOUSE (38-396): 9.46e-71: 233: 18.23
+	At
		1340744 DDB1A_ARATH (2-1134): 0: 1154: 32.70		Q9M1E5_ARATH (31-396): 9.96e-88: 282: 20.89
+	At
		221833 DDB1B_ARATH (3-1134): 0: 1141: 32.64		Q9M1E5_ARATH (31-396): 9.96e-88: 282: 20.89
+	Zm
		37968 A0A1D6ME60_MAIZE (3-1134): 0: 1144: 33.07		B4FRU9_MAIZE (1-398): 1.4e-68: 232: 19.41
+	Mm
		1112265 DDB1_MOUSE (1-1134): 0: 1212: 36.43		WDTC1_MOUSE (52-236): 8.01e-18: 89.3: 26.04
+	Hs
		1082281 DDB1_HUMAN (1-1134): 0: 1209: 36.43		WDTC1_HUMAN (52-236): 7.21e-18: 89.7: 26.04
+	Hs
		1082327 DDB1_HUMAN (1-1134): 0: 1209: 36.43		SNR40_HUMAN (11-141): 2.03e-18: 89.3: 12.32
+	Hs
		1082263 DDB1_HUMAN (1-1134): 0: 1209: 36.43		WDR5B_HUMAN (332-523): 1.82e-16: 82.8: 10.58
+	Hs
		903254 DDB1_HUMAN (1-1134): 0: 1209: 36.43		WDR5_HUMAN (284-434): 5.46e-13: 72.4: 14.47
+	At
		1114755 DDB1A_ARATH (2-1134): 0: 1154: 32.70		PRL1_ARATH (340-550): 1.87e-19: 93.6: 12.61
+	At
		221824 DDB1B_ARATH (3-1134): 0: 1141: 32.64		PRL1_ARATH (340-550): 1.87e-19: 93.6: 12.61
+	Hs
		1073094 SF3B3_HUMAN (3-1130): 0: 1033: 18.17		FBXW7_HUMAN (233-538): 5.99e-29: 124: 9.87
+	Hs
		1073168 SF3B3_HUMAN (3-1130): 0: 1033: 18.17		NLE1_HUMAN (358-530): 3.77e-19: 92.8: 10.66
+	Sp
		143270 DDB1_SCHPO (3-1134): 0: 797: 22.10		IQW1_SCHPO (59-267): 3.89e-16: 84.3: 24.67