HitPredict

Interactor 1: PAXT1 (Q21738)
Partner of xrn-2 protein 1
Gene: paxt-1

Interactor 2: XRN2 (Q9U299)
5'-3' exoribonuclease 2 homolog (EC 3.1.13.-)
Gene: xrn-2

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.90	0.797

Property	Details
Experiments	24462208, 26779609
Identification Methods	affinity chromatography technology, x-ray crystallography, light scattering, pull down, molecular sieving, thermal shift binding
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	XRN_M~XTBD
Common GO terms	GO:0005634 - nucleus GO:0005730 - nucleolus GO:0006397 - mRNA processing GO:0010587 - miRNA catabolic process GO:0060965 - negative regulation of miRNA-mediated gene silencing
Homologous interactions	0