Interactor 1: PUR8 (Q21774)
Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase)
Gene: adsl-1

Interactor 2: PUR8 (Q21774)
Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase)
Gene: adsl-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.853

The method score is based on:

Property Details
Experiments 19123269, 18692475, unassigned701
Identification Methods two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Lyase_1~Lyase_1
Common GO terms GO:0004018 - N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
GO:0005829 - cytosol
GO:0006189 - 'de novo' IMP biosynthetic process
GO:0044208 - 'de novo' AMP biosynthetic process
GO:0070626 - (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 478
Ce

1 478
+ Sc
+ Sp
+ Hs
+ Sp
+ Sp
+ At
+ Sp
+ Ms
+ Cj
+ Cj
+ Cj
+ Mt
+ Cj

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Last updated: 15 Jul 2024