Protein: K2C1B
Keratin, type II cytoskeletal 1b (Cytokeratin-1B) (CK-1B) (Keratin-77) (K77) (Type-II keratin Kb39)

Gene: K2C1B, KRT77
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q7Z794

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0030280 - structural constituent of skin epidermis
GO:0031424 - keratinization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

580056

K1C15
Keratin, type I cytoskeletal 15

3

20

High-throughput

0.845

High

1071240

K1H1
Keratin, type I cuticular Ha1

3

20

High-throughput

0.845

High

280811

KRT36
Keratin, type I cuticular Ha6

2

20

High-throughput

0.783

High

444407

K1C19
Keratin, type I cytoskeletal 19

2

20

High-throughput

0.783

High

1189590

K1C27
Keratin, type I cytoskeletal 27

2

20

High-throughput

0.783

High

1192453

KRT35
Keratin, type I cuticular Ha5

2

20

High-throughput

0.783

High

980281

K1C17
Keratin, type I cytoskeletal 17

1

20

High-throughput

0.665

High

280623

KRT34
Keratin, type I cuticular Ha4

1

20

High-throughput

0.621

High

359378

K1C14
Keratin, type I cytoskeletal 14

1

20

High-throughput

0.621

High

445079

K1C16
Keratin, type I cytoskeletal 16

1

20

High-throughput

0.621

High

1055061

KT33B
Keratin, type I cuticular Ha3-II

1

20

High-throughput

0.621

High

1189695

K1C25
Keratin, type I cytoskeletal 25

1

20

High-throughput

0.621

High

927229

1433Z
14-3-3 protein zeta/delta

2

20

Small-scale

0.584

High

529349

CFTR
Cystic fibrosis transmembrane conductance regulator

1

17

High-throughput

0.536

High

1192454

CUL5
Cullin-5

1

20

High-throughput

0.536

High

1192457

DCNL1
DCN1-like protein 1

1

3

High-throughput

0.536

High

1062757

FL2D
Pre-mRNA-splicing regulator WTAP

1

7

High-throughput

0.489

High

1192467

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

13

High-throughput

0.489

High

134103

DDX3X
ATP-dependent RNA helicase DDX3X

1

5

Small-scale

0.479

High

282686

RNF8
E3 ubiquitin-protein ligase RNF8

1

13

High-throughput

0.479

High

369912

ESR1
Estrogen receptor

1

14

High-throughput

0.479

High

374456

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.479

High

387010

P53
Cellular tumor antigen p53

1

8

Small-scale

0.479

High

568719

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

7

Small-scale

0.479

High

666134

SHC1
SHC-transforming protein 1

1

20

High-throughput

0.479

High

683500

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.479

High

684163

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

802644

CRK
Adapter molecule crk

1

20

High-throughput

0.479

High

904786

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

909746

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.479

High

982214

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1033671

IKZF1
DNA-binding protein Ikaros

1

5

High-throughput

0.479

High

1116363

LARP7
La-related protein 7

1

10

High-throughput

0.479

High

1163729

RICTR
Rapamycin-insensitive companion of mTOR

1

6

High-throughput

0.479

High

1192455

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

7

Small-scale

0.479

High

1192456

AP2M1
AP-2 complex subunit mu

1

7

High-throughput

0.479

High

1192465

CCDC8
Coiled-coil domain-containing protein 8

1

4

High-throughput

0.479

High

1192466

RN208
RING finger protein 208

1

20

Small-scale

0.479

High

1192468

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

10

High-throughput

0.479

High

1192469

ANLN
Anillin

1

11

High-throughput

0.479

High

1192471

HDAC6
Histone deacetylase 6

1

12

High-throughput

0.479

High

1192472

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

1192473

IKZF3
Zinc finger protein Aiolos

1

4

High-throughput

0.479

High

1192449

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

1192459

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

319900

HERC2
E3 ubiquitin-protein ligase HERC2

1

2

High-throughput

0.445

High

717975

BMI1
Polycomb complex protein BMI-1

1

13

High-throughput

0.445

High

808737

YAP1
Transcriptional coactivator YAP1

1

17

High-throughput

0.445

High

891201

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

1192450

KIBRA
Protein KIBRA

1

18

High-throughput

0.445

High

1192462

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

20

High-throughput

0.445

High

1192464

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.445

High

229959

NUAK1
NUAK family SNF1-like kinase 1

1

2

High-throughput

0.437

High

303336

HEXI1
Protein HEXIM1

1

18

High-throughput

0.437

High

329814

AGR2
Anterior gradient protein 2 homolog

1

3

High-throughput

0.437

High

347191

MYC
Myc proto-oncogene protein

1

12

High-throughput

0.437

High

379559

MYCN
N-myc proto-oncogene protein

1

12

High-throughput

0.437

High

1018554

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.437

High

1046088

DX39B
Spliceosome RNA helicase DDX39B

1

20

High-throughput

0.437

High

1059702

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.437

High

1062241

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

2

High-throughput

0.437

High

1080082

EZH2
Histone-lysine N-methyltransferase EZH2

1

8

High-throughput

0.437

High

1173977

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

5

High-throughput

0.437

High

1184186

MEPCE
7SK snRNA methylphosphate capping enzyme

1

10

High-throughput

0.437

High

1192452

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

4

High-throughput

0.437

High

1192461

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

5

High-throughput

0.437

High

1192463

DDX24
ATP-dependent RNA helicase DDX24

1

19

High-throughput

0.437

High

1192460

ATGA1
Autophagy-related protein 101

1

0

High-throughput

0.426

High

1077

SIM26
Small integral membrane protein 26

1

6

High-throughput

0.407

High

1047141

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

6

High-throughput

0.407

High

1192451

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.407

High

1192458

MDFI
MyoD family inhibitor

2

0

High-throughput

0.316

High

1192470

IKBL1
NF-kappa-B inhibitor-like protein 1

1

0

High-throughput

0.278

Low


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Last updated: 15 Jul 2024