HitPredict

Interactor 1: PSF1 (Q22019)
Probable DNA replication complex GINS protein PSF1 (GINS complex subunit 1)
Gene: psf-1

Interactor 2: MCM4 (Q95XQ8)
DNA replication licensing factor mcm-4 (EC 3.6.4.12)
Gene: mcm-4

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	28368371
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	MCM~Sld5, MCM_N~Sld5
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 201 Ce			1 823
+	Hs
		832463 PSF1_HUMAN (13-200): 5.88e-89: 261: 40.31		MCM2_HUMAN (13-803): 0: 736: 28.41
+	Hs
		708646 PSF1_HUMAN (13-200): 5.88e-89: 261: 40.31		MCM5_HUMAN (92-822): 0: 684: 27.97
+	Dm
		1366525 Q9W0I7_DROME (12-200): 2.48e-86: 254: 37.82		MCM5_DROME (92-819): 0: 666: 28.14
+	Hs
		1058096 PSF1_HUMAN (13-200): 5.88e-89: 261: 40.31		MCM8_HUMAN (64-822): 0: 656: 24.19
+	Ce
		1094509 PSF1_CAEEL (1-201): 1.69e-99: 288: 100.00		MCM5_CAEEL (112-819): 0: 627: 27.80
+	Hs
		708909 PSF1_HUMAN (13-200): 5.88e-89: 261: 40.31		MCM7_HUMAN (113-819): 0: 641: 28.97
+	Sc
		675576 PSF1_YEAST (12-200): 2.03e-57: 181: 27.27		MCM4_YEAST (5-818): 0: 705: 38.02
+	Sc
		667904 PSF1_YEAST (12-200): 2.03e-57: 181: 27.27		MCM5_YEAST (116-764): 0: 658: 28.95
+	Sc
		667656 PSF1_YEAST (12-200): 2.03e-57: 181: 27.27		MCM2_YEAST (10-744): 0: 646: 26.20
+	Ce
		183740 PSF1_CAEEL (1-201): 1.69e-99: 288: 100.00		O16297_CAEEL (234-744): 1.48e-95: 316: 37.27
+	Sc
		859034 PSF1_YEAST (12-200): 2.03e-57: 181: 27.27		MCM6_YEAST (226-735): 4.11e-94: 318: 36.03