Interactor 1: TRAF3 (Q13114)
TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3)
Gene: TRAF3

Interactor 2: STING (Q86WV6)
Stimulator of interferon genes protein (hSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (hMITA) (Transmembrane protein 173)
Gene: STING1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.676

The method score is based on:

Property Details
Experiments 27716849, 37130168, 24622840, 18818105
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005768 - endosome
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
GO:0031625 - ubiquitin protein ligase binding
GO:0032481 - positive regulation of type I interferon production
and 3 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 568
Hs

1 379
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm

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Last updated: 11Aug2025