HitPredict

Interactor 1: MIG15 (Q23356)
Serine/threonine-protein kinase mig-15 (EC 2.7.11.1) (Abnormal cell migration protein 15)
Gene: mig-15

Interactor 2: Q95PW9 (Q95PW9)
NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family
Gene: nck-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016310 - phosphorylation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1096 Ce			1 395
+	Dm
		1182596 Q7KV88_DROME (5-1096): 0: 991: 50.73		NCK_DROME (5-395): 9.5e-61: 207: 33.72
+	Dm
		993188 Q7KV89_DROME (5-1096): 0: 993: 50.91		GRAP_DROME (2-59): 1.56e-15: 76.7: 27.59
+	Hs
		209164 SIK2_HUMAN (10-721): 1.2e-129: 419: 17.44		NCK2_HUMAN (2-393): 1.95e-85: 266: 37.31
+	Hs
		209186 TNIK_HUMAN (3-765): 1.64e-117: 396: 36.34		NCK2_HUMAN (2-393): 1.95e-85: 266: 37.31
+	Hs
		209112 MINK1_HUMAN (3-784): 3.36e-117: 394: 36.68		NCK2_HUMAN (2-393): 1.95e-85: 266: 37.31
+	Hs
		557820 TNIK_HUMAN (3-765): 1.64e-117: 396: 36.34		NCK1_HUMAN (2-394): 6.74e-80: 252: 37.78
+	Hs
		557740 MINK1_HUMAN (3-784): 3.36e-117: 394: 36.68		NCK1_HUMAN (2-394): 6.74e-80: 252: 37.78
+	Hs
		411778 MARK2_HUMAN (4-694): 3.71e-134: 427: 15.19		LCK_HUMAN (176-378): 5.2e-55: 190: 30.05
+	Hs
		411606 MARK3_HUMAN (14-637): 1.59e-123: 398: 16.79		LCK_HUMAN (176-378): 5.2e-55: 190: 30.05
+	Hs
		411790 MINK1_HUMAN (3-784): 3.36e-117: 394: 36.68		LCK_HUMAN (176-378): 5.2e-55: 190: 30.05
+	Hs
		681710 AKT1_HUMAN (2-360): 2.73e-124: 391: 21.72		CSK_HUMAN (207-392): 2.5e-34: 134: 27.81
+	Hs
		655461 SIK2_HUMAN (10-721): 1.2e-129: 419: 17.44		P85A_HUMAN (270-393): 4.44e-20: 94.5: 19.69
+	Hs
		924703 MINK1_HUMAN (3-784): 3.36e-117: 394: 36.68		GRB2_HUMAN (5-175): 1.72e-28: 112: 20.37
+	Hs
		433470 SIK2_HUMAN (10-721): 1.2e-129: 419: 17.44		YES_HUMAN (5-108): 6.99e-17: 84.4: 17.93
+	Hs
		655233 AKT1_HUMAN (2-360): 2.73e-124: 391: 21.72		P85A_HUMAN (270-393): 4.44e-20: 94.5: 19.69
+	Mm
		643056 AKT1_MOUSE (2-360): 1.47e-124: 391: 21.72		P85A_MOUSE (270-393): 5.53e-20: 94.1: 19.69
+	Hs
		412163 STK4_HUMAN (6-407): 3.01e-125: 393: 35.58		FYN_HUMAN (6-244): 7.07e-19: 90.2: 12.45
+	Hs
		412046 AKT1_HUMAN (2-360): 2.73e-124: 391: 21.72		FYN_HUMAN (6-244): 7.07e-19: 90.2: 12.45
+	Hs
		522810 AKT1_HUMAN (2-360): 2.73e-124: 391: 21.72		SRC_HUMAN (43-217): 1.14e-12: 71.3: 16.95
+	Mm
		403418 AKT1_MOUSE (2-360): 1.47e-124: 391: 21.72		SRC_MOUSE (43-180): 9.38e-12: 68.3: 21.58