Protein: H2A1C
Histone H2A type 1-C (H2A-clustered histone 6) (Histone H2A/l)

Gene: H2A1C, H2AC6
Organism: Homo sapiens
Interactions: 98
UniProt ID: Q93077

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008285 - negative regulation of cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1163119

H2B2E
Histone H2B type 2-E

3

20

High-throughput

0.847

High

1258903

H32
Histone H3.2

3

20

High-throughput

0.827

High

521842

H14
Histone H1.4

2

20

High-throughput

0.754

High

659927

H2B1O
Histone H2B type 1-O

2

20

High-throughput

0.754

High

946849

H2B1D
Histone H2B type 1-D

2

20

High-throughput

0.754

High

980093

H4
Histone H4

2

15

High-throughput

0.754

High

980985

H2B1C
Histone H2B type 1-C/E/F/G/I

2

20

High-throughput

0.754

High

998642

H31
Histone H3.1

2

20

High-throughput

0.754

High

1372240

H2B1L
Histone H2B type 1-L

2

20

High-throughput

0.754

High

502084

H2AZ
Histone H2A.Z

1

20

High-throughput

0.691

High

1372249

WDR76
WD repeat-containing protein 76

1

15

High-throughput

0.691

High

856847

BAG6
Large proline-rich protein BAG6

1

20

High-throughput

0.665

High

231160

AIRE
Autoimmune regulator

1

20

Small-scale

0.618

High

256943

H2B1K
Histone H2B type 1-K

1

20

High-throughput

0.618

High

355574

NSD2
Histone-lysine N-methyltransferase NSD2

1

16

High-throughput

0.618

High

419124

H2A1B
Histone H2A type 1-B/E

1

19

High-throughput

0.618

High

449767

H2B1J
Histone H2B type 1-J

1

20

High-throughput

0.618

High

455838

H10
Histone H1.0

1

5

High-throughput

0.618

High

502465

H2A1
Histone H2A type 1

1

19

High-throughput

0.618

High

595543

H15
Histone H1.5

1

20

High-throughput

0.618

High

595836

H13
Histone H1.3

1

20

High-throughput

0.618

High

596282

H12
Histone H1.2

1

20

High-throughput

0.618

High

634050

H2A1D
Histone H2A type 1-D

1

19

High-throughput

0.618

High

649384

H1T
Histone H1t

1

20

High-throughput

0.618

High

754933

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.618

High

888231

MCM2
DNA replication licensing factor MCM2

1

20

High-throughput

0.618

High

943399

H2BFS
Histone H2B type F-S

1

20

High-throughput

0.618

High

970880

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

9

High-throughput

0.618

High

987436

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

17

High-throughput

0.618

High

1017083

H33
Histone H3.3

1

20

High-throughput

0.618

High

1037302

H11
Histone H1.1

1

20

High-throughput

0.618

High

1161983

H31T
Histone H3.1t

1

20

High-throughput

0.618

High

1162857

H2A2C
Histone H2A type 2-C

1

19

High-throughput

0.618

High

1208865

H2B2F
Histone H2B type 2-F

1

20

High-throughput

0.618

High

1216184

DDI2
Protein DDI1 homolog 2

1

3

High-throughput

0.618

High

1232705

H2A2A
Histone H2A type 2-A

1

19

High-throughput

0.618

High

1239460

H3C
Histone H3.3C

1

20

High-throughput

0.618

High

1272808

H2A3
Histone H2A type 3

1

20

High-throughput

0.618

High

1307289

H2A2B
Histone H2A type 2-B

1

19

High-throughput

0.618

High

1323949

H2B3B
Histone H2B type 3-B

1

20

High-throughput

0.618

High

1372234

H2B1A
Histone H2B type 1-A

1

20

High-throughput

0.618

High

1372235

H2A1H
Histone H2A type 1-H

1

19

High-throughput

0.618

High

1372237

H2A1A
Histone H2A type 1-A

1

19

High-throughput

0.618

High

1372238

H2B1N
Histone H2B type 1-N

1

20

High-throughput

0.618

High

1372239

H2A1J
Histone H2A type 1-J

1

19

High-throughput

0.618

High

1372242

H2AJ
Histone H2A.J

1

19

High-throughput

0.618

High

487609

PARP1
Poly [ADP-ribose] polymerase 1

2

20

High-throughput

0.611

High

436711

KPCB
Protein kinase C beta type

2

10

High-throughput

0.571

High

702363

ELK4
ETS domain-containing protein Elk-4

2

9

High-throughput

0.571

High

908152

KS6A3
Ribosomal protein S6 kinase alpha-3

2

8

High-throughput

0.571

High

1145903

RBP1
RalA-binding protein 1

2

4

High-throughput

0.571

High

1372247

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

2

10

High-throughput

0.571

High

1372251

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

2

3

High-throughput

0.571

High

542604

TOP2A
DNA topoisomerase 2-alpha

1

7

High-throughput

0.536

High

601798

HMGA1
High mobility group protein HMG-I/HMG-Y

1

6

High-throughput

0.536

High

1134673

NUMA1
Nuclear mitotic apparatus protein 1

1

12

High-throughput

0.536

High

1372246

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

2

High-throughput

0.536

High

167344

KLF11
Krueppel-like factor 11

1

2

High-throughput

0.515

High

869773

MTR1A
Melatonin receptor type 1A

1

2

High-throughput

0.494

High

909125

NEK4
Serine/threonine-protein kinase Nek4

1

16

High-throughput

0.489

High

248028

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

297666

PIAS1
E3 SUMO-protein ligase PIAS1

1

1

High-throughput

0.479

High

325031

HEXI1
Protein HEXIM1

1

12

High-throughput

0.479

High

331210

KI20A
Kinesin-like protein KIF20A

1

16

High-throughput

0.479

High

349188

LATS1
Serine/threonine-protein kinase LATS1

1

5

High-throughput

0.479

High

424443

HMGN1
Non-histone chromosomal protein HMG-14

1

4

High-throughput

0.479

High

426547

HMGN2
Non-histone chromosomal protein HMG-17

1

10

High-throughput

0.479

High

520616

RARA
Retinoic acid receptor alpha

1

8

Small-scale

0.479

High

552340

ADT3
ADP/ATP translocase 3

1

3

High-throughput

0.479

High

565441

ITA4
Integrin alpha-4

1

5

High-throughput

0.479

High

755998

MCM5
DNA replication licensing factor MCM5

1

20

High-throughput

0.479

High

776840

MYH11
Myosin-11

1

1

High-throughput

0.479

High

831185

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

915473

HMGA2
High mobility group protein HMGI-C

1

5

Small-scale

0.479

High

983920

RBX1
E3 ubiquitin-protein ligase RBX1

1

4

High-throughput

0.479

High

1095287

REST
RE1-silencing transcription factor

1

2

High-throughput

0.479

High

1120274

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

20

Small-scale

0.479

High

1194262

LARP7
La-related protein 7

1

20

High-throughput

0.479

High

1271771

MEPCE
7SK snRNA methylphosphate capping enzyme

1

12

High-throughput

0.479

High

1281580

SLN11
Schlafen family member 11

1

6

High-throughput

0.479

High

1334724

SERB1
SERPINE1 mRNA-binding protein 1

1

11

High-throughput

0.479

High

1372236

CI072
Guanine nucleotide exchange factor C9orf72

1

10

High-throughput

0.479

High

1372241

VRK1
Serine/threonine-protein kinase VRK1

1

3

High-throughput

0.479

High

1372244

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

17

High-throughput

0.479

High

1372245

FACD2
Fanconi anemia group D2 protein

1

9

High-throughput

0.479

High

1372250

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

5

High-throughput

0.479

High

1372253

RT18B
Small ribosomal subunit protein mS40

1

2

High-throughput

0.479

High

1372243

HEMGN
Hemogen

1

0

Small-scale

0.460

High

1339122

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1372252

ICE1
Little elongation complex subunit 1

1

0

High-throughput

0.458

High

1363178

AP2B
Transcription factor AP-2-beta

1

0

High-throughput

0.438

High

157706

CTRO
Citron Rho-interacting kinase

1

11

High-throughput

0.437

High

1254933

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.437

High

1360111

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

4

High-throughput

0.437

High

1372248

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1252919

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

1358078

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.249

Low

1372233

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025